Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Seong Hoon Yun"'
Autor:
Hyoju Jeon, Chang-Gun Lee, Hyesoo Jeong, Seong-Hoon Yun, Jeonghyun Kim, Laxmi Prasad Uprety, Kang-Il Oh, Shivani Singh, Jisu Yoo, Eunkuk Park, Seon-Yong Jeong
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4752 (2023)
Obesity is characterized by the excessive accumulation of mature adipocytes that store surplus energy in the form of lipids. In this study, we investigated the inhibitory effects of loganin on adipogenesis in mouse preadipocyte 3T3-L1 cells and prima
Externí odkaz:
https://doaj.org/article/b8ebd1b112c049988d0bda588a05d346
Autor:
Seong-Hoon Yun, Joo-In Park
Publikováno v:
Journal of International Medical Research, Vol 48 (2020)
Chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII) is an orphan receptor that regulates the expression of genes involved in development and homeostasis. COUP-TFII is also dysregulated in cancer, where it plays important roles in
Externí odkaz:
https://doaj.org/article/261329411e964b6f9b9d57bbf6a04cc7
Autor:
Jong-Young Kwak, Joo-In Park, Valentin A. Stonik, Valeria V. Shastina, Jin-Sook Jeong, Jin-Yeong Han, Yong-Woo Na, Sung-Won Shin, Eun-Seon Park, Seong-Hoon Yun
PDF file - 1.8MB, Antioxidants inhibit the activation of neutral SMase and BSO enhances the activation of neutral SMase by STC in human leukemic cells. (A to C) HL-60 and K562 cells (1 �~ 105 cells/ well) were incubated with STC in the presence or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0e4d1ec248ad3f113f52550752cab8
https://doi.org/10.1158/1078-0432.22445340.v1
https://doi.org/10.1158/1078-0432.22445340.v1
Autor:
Jong-Young Kwak, Joo-In Park, Valentin A. Stonik, Valeria V. Shastina, Jin-Sook Jeong, Jin-Yeong Han, Yong-Woo Na, Sung-Won Shin, Eun-Seon Park, Seong-Hoon Yun
PDF file - 1MB, Depletion of GSH and production of ROS may contribute to STC-induced apoptosis in human leukemic and colorectal cancer cells. (A) HL-60, K562, HT-29, and SNU-C4 cells were treated with STC (0.3, 0.5 muM) or STC (1.0, 1.5 muM) for 2 h,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c410434cd303facc2146413428b70544
https://doi.org/10.1158/1078-0432.22445346.v1
https://doi.org/10.1158/1078-0432.22445346.v1
Autor:
Jong-Young Kwak, Joo-In Park, Valentin A. Stonik, Valeria V. Shastina, Jin-Sook Jeong, Jin-Yeong Han, Yong-Woo Na, Sung-Won Shin, Eun-Seon Park, Seong-Hoon Yun
PDF file - 2.3MB, Treatment of colorectal cancer cells with STC leads to generation of ceramide through the activation of acid SMase and neutral SMase. (A and B) CT-26 cells (1 �~ 105 cells/well) were incubated with STC in the presence or absence o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3040778df423895a2a54779c633dc9a2
https://doi.org/10.1158/1078-0432.22445352
https://doi.org/10.1158/1078-0432.22445352
Autor:
Jong-Young Kwak, Joo-In Park, Valentin A. Stonik, Valeria V. Shastina, Jin-Sook Jeong, Jin-Yeong Han, Yong-Woo Na, Sung-Won Shin, Eun-Seon Park, Seong-Hoon Yun
PDF file - 1.8MB, GSH inhibits STC-induced neutral SMase activation, but it does not inhibit activation of Fas and acid SMase by STC in human leukemic and colorectal cancer cells. (A) HL-60 cells were treated with STC (0.3 muM) for 2 h in the presenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ac33dc6ba7078b9c08711f674d22b7
https://doi.org/10.1158/1078-0432.22445343
https://doi.org/10.1158/1078-0432.22445343
Autor:
Jong-Young Kwak, Joo-In Park, Valentin A. Stonik, Valeria V. Shastina, Jin-Sook Jeong, Jin-Yeong Han, Yong-Woo Na, Sung-Won Shin, Eun-Seon Park, Seong-Hoon Yun
PDF file - 2MB, Treatment of HL-60 and human primary leukemia cells with STC leads to generation of ceramide through the activation of Fas, acid SMase and neutral SMase. (A) HL-60 cells were treated with STC (0.3 muM) for 2 h and were then fixed. Fol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ee1a539d8a65440d50a3976a78b16d7
https://doi.org/10.1158/1078-0432.22445355.v1
https://doi.org/10.1158/1078-0432.22445355.v1
Autor:
Jong-Young Kwak, Joo-In Park, Valentin A. Stonik, Valeria V. Shastina, Jin-Sook Jeong, Jin-Yeong Han, Yong-Woo Na, Sung-Won Shin, Eun-Seon Park, Seong-Hoon Yun
PDF file - 2.3MB, Activation of acid and neutral SMase by STC is independent from activation of Fas and caspase-8. (A) HL-60 and K562 cells were incubated with STC (0.3 muM or 0.5 muM, respectively) in the presence or absence of desipramine or GW4869
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e59cb5a56fe0d7cf5973d9a1762fc56
https://doi.org/10.1158/1078-0432.22445349
https://doi.org/10.1158/1078-0432.22445349
Autor:
Eunkuk Park, Chang Gun Lee, Seung Hee Yun, Seokjin Hwang, Hyoju Jeon, Jeonghyun Kim, Subin Yeo, Hyesoo Jeong, Seong-Hoon Yun, Seon-Yong Jeong
Publikováno v:
Pharmaceuticals, Vol 14, Iss 2, p 135 (2021)
Arthritis is a common inflammatory disease that causes pain, stiffness, and joint swelling. Here, we investigated the ameliorative effects of loganin on arthritis in vitro and in vivo. A single bioactive compound was fractionated and isolated from Co
Externí odkaz:
https://doaj.org/article/c518c8715fd8401c85c4405ca6b27218
Autor:
Eunkuk Park, Chang Gun Lee, Eunguk Lim, Seokjin Hwang, Seung Hee Yun, Jeonghyun Kim, Hyesoo Jeong, Yoonjoong Yong, Seong-Hoon Yun, Chun Whan Choi, Hyun-Seok Jin, Seon-Yong Jeong
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1, p 233 (2020)
Osteoporosis is a common disease caused by an imbalance of processes between bone resorption by osteoclasts and bone formation by osteoblasts in postmenopausal women. The roots of Gentiana lutea L. (GL) are reported to have beneficial effects on vari
Externí odkaz:
https://doaj.org/article/94e888c6d61f44b2909462634e76b169