Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Seong H. Chow"'
Outer membrane vesicles from Neisseria gonorrhoeae target PorB to mitochondria and induce apoptosis.
Autor:
Pankaj Deo, Seong H Chow, Iain D Hay, Oded Kleifeld, Adam Costin, Kirstin D Elgass, Jhih-Hang Jiang, Georg Ramm, Kipros Gabriel, Gordon Dougan, Trevor Lithgow, Eva Heinz, Thomas Naderer
Publikováno v:
PLoS Pathogens, Vol 14, Iss 3, p e1006945 (2018)
Neisseria gonorrhoeae causes the sexually transmitted disease gonorrhoea by evading innate immunity. Colonizing the mucosa of the reproductive tract depends on the bacterial outer membrane porin, PorB, which is essential for ion and nutrient uptake.
Externí odkaz:
https://doaj.org/article/19a370dd541c457a8aeece8ff5d25289
Autor:
Seong H, Chow, Thomas, Naderer
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2523
The NLRP3 inflammasome senses the activity of pore-forming toxins secreted by Staphylococcus aureus. The bacterial toxins compromise plasma membrane integrity which activates the NLRP3 inflammasome to induce host pore-forming proteins and cellular su
Autor:
Subhash Dhital, Pankaj Deo, Manasa Bharathwaj, Kristy Horan, Joshua Nickson, Mohammad Azad, Isabella Stuart, Seong H Chow, Sachith D Gunasinghe, Rebecca Bamert, Jian Li, Trevor Lithgow, Benjamin P Howden, Thomas Naderer
Publikováno v:
microLife. 3
Neisseria gonorrhoeae causes the sexually transmitted disease gonorrhoea. The treatment of gonorrhoea is becoming increasingly challenging, as N. gonorrhoeae has developed resistance to antimicrobial agents routinely used in the clinic. Resistance to
Autor:
Seong H. Chow, Thomas Naderer
Publikováno v:
Methods in Molecular Biology ISBN: 9781071624487
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3c8c742114fd095cf37161d264e8ea7
https://doi.org/10.1007/978-1-0716-2449-4_15
https://doi.org/10.1007/978-1-0716-2449-4_15
Autor:
Daniel S. Simpson, Jiyi Pang, Ashley Weir, Isabella Y. Kong, Melanie Fritsch, Maryam Rashidi, James P. Cooney, Kathryn C. Davidson, Mary Speir, Tirta M. Djajawi, Sebastian Hughes, Liana Mackiewicz, Merle Dayton, Holly Anderton, Marcel Doerflinger, Yexuan Deng, Allan Shuai Huang, Stephanie A. Conos, Hazel Tye, Seong H. Chow, Arfatur Rahman, Raymond S. Norton, Thomas Naderer, Sandra E. Nicholson, Gaetan Burgio, Si Ming Man, Joanna R. Groom, Marco J. Herold, Edwin D. Hawkins, Kate E. Lawlor, Andreas Strasser, John Silke, Marc Pellegrini, Hamid Kashkar, Rebecca Feltham, James E. Vince
Publikováno v:
Immunity. 55:423-441.e9
Cell death plays an important role during pathogen infections. Here, we report that interferon-γ (IFNγ) sensitizes macrophages to Toll-like receptor (TLR)-induced death that requires macrophage-intrinsic death ligands and caspase-8 enzymatic activi
Publikováno v:
Cellular microbiology. 18(4)
Macrophages can respond to microbial infections with programmed cell death. The major cell death pathways of apoptosis, pyroptosis and necroptosis are tightly regulated to ensure adequate immune reactions to virulent and persistent invaders. Macropha