Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Seong Ae Yoon"'
Autor:
Seong-Ae Yoon, Jeong-Oh Kim, Jung-Young Shin, Jin-Hyoung Kang, Jung Ran Choi, Xiang-Hua Zhang
Publikováno v:
Journal of Life Science. 20:103-112
Pemetrexed has demonstrated clinical activity in non-small cell lung cancer (NSCLC) as well as other solid tumors. It transports into the cells via reduced folate carrier (RFC) and is polyglutamated by folypolyglutamate synthetase (FPGS). Pemetrexed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6e3130779604fb23afaeddf66657d14
https://doi.org/10.5352/jls.2010.20.1.103
https://doi.org/10.5352/jls.2010.20.1.103
Autor:
Jung-Young Shin, Seong-Ae Yoon, Ji Eun Oh, Chan Kwon Jung, Jin-Hyoung Kang, Jeong-Oh Kim, Xiang-Hua Zhang
Publikováno v:
Cancer letters. 322(2)
Studies on non-small cell lung cancer (NSCLC) patients with KRAS or BRAF mutations are urgently needed to improve clinical outcomes. We evaluated the cytotoxicities of paclitaxel and sorafenib alone and in combination in NSCLC cell lines with KRAS or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25475d76c64a71508b95d05eb248899d
https://pubmed.ncbi.nlm.nih.gov/22433711
https://pubmed.ncbi.nlm.nih.gov/22433711
Autor:
Ki-Dong Yoo, Hyung Joo Hong, Jin-Hyoung Kang, Jung Ran Choi, Xiang-Hua Zhang, Ho-Jung Yun, Kwang-Soo Lee, Myeon Woo Chung, Hyun Joo Park, Yong-Seog Oh, Seong-Ae Yoon, Jung-Young Shin, Yoon Sook Lee, Mee Ork Roh, Tae Sun Kang, Dae Ryong Kang, Young-Pil Wang, Hee-Gyeong Jeon, Keon-Hyon Jo, Jeong-Oh Kim
Publikováno v:
Journal of human genetics. 56(4)
Warfarin is a commonly prescribed anticoagulant drug for the prevention of thromboembolic disorders. We investigated the contribution of genetic variations of four genes and clinical factors to warfarin dose requirement and provided a warfarin-dosing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4558603f40d317a9cfdd442a80224fee
https://pubmed.ncbi.nlm.nih.gov/21326313
https://pubmed.ncbi.nlm.nih.gov/21326313
Publikováno v:
Journal of microbiology and biotechnology. 18(3)
An extracellular enzyme (RMEBE) possessing alpha- (1--4)-(1--6)-transferring activity was purified to homogeneity from Rhodothermus marinus by combination of ammonium sulfate precipitation, Q-Sepharose ion-exchange, and Superdex- 200 gel filtration c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d2ae830e7ffd0d136b2365c7037f42dc
https://pubmed.ncbi.nlm.nih.gov/18388462
https://pubmed.ncbi.nlm.nih.gov/18388462
Autor:
Xiang-Hua Zhang, Seong-Ae Yoon, Sook-Hee Hong, Jin-Hyoung Kang, Myung-Hee Chang, Jung-Young Shin
Publikováno v:
Cancer Research. 70:3618-3618
Sorafenib (BAY 43-9006), a multi-kinase inhibitor, targets a serine-threonine kinase, BRAF as well as several tyrosine kinases. Paclitaxel has been known to exhibit potent anti-tumor activity in non-small cell lung cancer (NSCLC). Our aim of this stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a3bf826d9b0dfef0a78063e8fcead46
https://doi.org/10.1158/1538-7445.am10-3618
https://doi.org/10.1158/1538-7445.am10-3618
Publikováno v:
Cancer Research. 70:1582-1582
It has been known that Rho GDP dissociation inhibitor 2 (RhoGDI2) is a regulator of Rho family GTPase. We identified a RhoGDI2 protein through the protein expression profile and then investigated its functional role on EGFR downstream signal in NSCLC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91fbaeebb6716318e82e06aef766a1cb
https://doi.org/10.1158/1538-7445.am10-1582
https://doi.org/10.1158/1538-7445.am10-1582
Autor:
Jeong Oh Kim, Xiang-Hua Zhang, Jung Young Shin, Jung Ran Choi, Jin Hyoung Kang, Seong Ae Yoon
Publikováno v:
Cancer Research and Treatment. 42:163
Purpose The aim of this study is to investigate the effect of genetic variations and the expression of the reduced folate carrier (RFC) and dihydrofolate reductase (DHFR) on the drug sensitivity to methotrexate (MTX) in different cancer cell lines. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86e46e881dce53bd5671256d9888acc8
https://doi.org/10.4143/crt.2010.42.3.163
https://doi.org/10.4143/crt.2010.42.3.163
Publikováno v:
Molecular Cancer Therapeutics. 8:A81-A81
Background: Sorafenib (BAY 43-9006) is a multi-kinase inhibitor that targets a serine-threonine kinase, B-Raf as well as several tyrosine kinases. Given the numerous molecular targets of sorafenib, several potential mechanisms of its inhibitory activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75e8e9fa1e6eccda616570bc09ae5c50
https://doi.org/10.1158/1535-7163.targ-09-a81
https://doi.org/10.1158/1535-7163.targ-09-a81