Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Seong–Kyu CHOE"'
Autor:
Raghbendra Kumar Dutta, Joon No Lee, Yunash Maharjan, Channy Park, Seong-Kyu Choe, Ye-Shih Ho, Hyug Moo Kwon, Raekil Park
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-22 (2022)
Abstract Background Lysosomes are a central hub for cellular metabolism and are involved in the regulation of cell homeostasis through the degradation or recycling of unwanted or dysfunctional organelles through the autophagy pathway. Catalase, a per
Externí odkaz:
https://doaj.org/article/067ba67b1b244640b7815c216390c186
Autor:
Raghbendra Kumar Dutta, Joon No Lee, Yunash Maharjan, Channy Park, Seong-Kyu Choe, Ye-Shih Ho, Raekil Park
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Background Fatty acids (FA) derived from adipose tissue and liver serve as the main fuel in thermogenesis of brown adipose tissue (BAT). Catalase, a peroxisomal enzyme, plays an important role in maintaining intracellular redox homeostasis b
Externí odkaz:
https://doaj.org/article/208e867d9a0047088f420329cb431928
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 6, Pp 2220-2230 (2021)
Abstract Background Sarcopenia is defined as muscle wasting, characterized by a progressive loss of muscle mass and function due to ageing. Diagnosis of sarcopenia typically involves both muscle imaging and the physical performance of people exhibiti
Externí odkaz:
https://doaj.org/article/29c556e9961a466e96cf4b0113a4b88d
Autor:
Jin Kyung Kim, Yi Sak Kim, Hye-Mi Lee, Hyo Sun Jin, Chiranjivi Neupane, Sup Kim, Sang-Hee Lee, Jung-Joon Min, Miwa Sasai, Jae-Ho Jeong, Seong-Kyu Choe, Jin-Man Kim, Masahiro Yamamoto, Hyon E. Choy, Jin Bong Park, Eun-Kyeong Jo
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter in neuronal systems, but the potential role for such neurotransmitters on the immune system are emerging. Here the authors show GABA signaling is linked to autophagy, enhancing the
Externí odkaz:
https://doaj.org/article/c8d77fa23b514ad384c99df5991f346a
Autor:
So Young Eun, Joon No Lee, In-Koo Nam, Zhi-qiang Liu, Hong-Seob So, Seong-Kyu Choe, RaeKil Park
Publikováno v:
Experimental and Molecular Medicine, Vol 50, Iss 4, Pp 1-12 (2018)
Metabolism: A safeguard against cellular starvation A protein essential for the formation of peroxisomes—cellular organelles that perform diverse metabolic functions—also regulates cellular ‘recycling centers’ that break biomolecules down int
Externí odkaz:
https://doaj.org/article/393114bfdee842129a6ff2c54811515c
Autor:
AiHua Shen, Hyung-Jin Kim, Gi-Su Oh, Su-Bin Lee, Seung Hoon Lee, Arpana Pandit, Dipendra Khadka, Seong-Kyu Choe, Sung Chul Kwak, Sei-Hoon Yang, Eun-Young Cho, Hyun-Seok Kim, Hail Kim, Raekil Park, Tae Hwan Kwak, Hong-Seob So
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Acute pancreatitis (AP) is a complicated disease without specific drug therapy. The cofactor nicotinamide adenine dinucleotide (NAD+) is an important regulator of cellular metabolism and homeostasis. However, it remains unclear whether modul
Externí odkaz:
https://doaj.org/article/a7012ccbdf9e48b2bfc3a7ac7980c0c4
Autor:
Hye-Lin Kim, Yunu Jung, Jinbong Park, Dong-Hyun Youn, JongWook Kang, Seona Lim, Beom Su Lee, Mi-Young Jeong, Seong-Kyu Choe, Raekil Park, Kwang Seok Ahn, Jae-Young Um
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Brown adipocytes dissipate energy as heat and hence have an important therapeutic capacity for obesity. Development of brown-like adipocytes (also called beige) is also another attractive target for obesity treatment. Here, we investigated the effect
Externí odkaz:
https://doaj.org/article/726dd8f372d9451895e2ae25ff315472
Autor:
Hara Lim, Jinbong Park, Hye-Lin Kim, JongWook Kang, Mi-Young Jeong, Dong-Hyun Youn, Yunu Jung, Yong-Il Kim, Hyun-Ju Kim, Kwang-Seok Ahn, Su-Jin Kim, Seong-Kyu Choe, Seung-Heon Hong, Jae-Young Um
Publikováno v:
Frontiers in Pharmacology, Vol 7 (2016)
Chrysophanic acid (CA) is a member of the anthraquinone family abundant in rhubarb, a widely used herb for obesity treatment in Traditional Korean Medicine. Though several studies have indicated numerous features of CA, no study has yet reported the
Externí odkaz:
https://doaj.org/article/14dc38aeec644bcba697aab9e17bbce0
Autor:
Kristen Alexa, Seong-Kyu Choe, Nicolas Hirsch, Letitiah Etheridge, Elizabeth Laver, Charles G Sagerström
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8261 (2009)
We have isolated and characterized a novel zebrafish pancreas mutant. Mutant embryos lack expression of isl1 and sst in the endocrine pancreas, but retain isl1 expression in the CNS. Non-endocrine endodermal gene expression is less affected in the mu
Externí odkaz:
https://doaj.org/article/5731903fa3a3444aba3211b39810f041
Autor:
Nicholas D. Demers, Victoria Riccio, Doo Sin Jo, Sushil Bhandari, Kelsey B. Law, Weifang Liao, Choy Kim, G. Angus McQuibban, Seong-Kyu Choe, Dong-Hyung Cho, Peter K. Kim
Publikováno v:
Autophagy. :1-22
Peroxisomes are rapidly degraded during amino acid and oxygen deprivation by a type of selective autophagy called pexophagy. However, how damaged peroxisomes are detected and removed from the cell is poorly understood. Recent studies suggest that the