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Supplementary Figure 1 from Novel Chemosensitive Single-Nucleotide Polymorphism Markers to Targeted Regimens in Metastatic Colorectal Cancer

Autor: Yong S. Kim, Hyoungseok Ju, Tae W. Kim, Seon A. Roh, Chan W. Kim, Eun Y. Choi, Ye J. Ha, Dong H. Cho, Seon Y. Kim, Jin C. Kim

PDF file - 376K, Inhibition rates (IR) of tumor growth (A) and response rates at IR30 (chemosensitivity) (B). The IRs and IR30 of a single bevacizumab or cetuximab regimen were significantly less than those of the other four combination regimens (P �

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a473ba7dea4671299522a34854e2ed29
https://doi.org/10.1158/1078-0432.22444835

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Data from Novel Chemosensitive Single-Nucleotide Polymorphism Markers to Targeted Regimens in Metastatic Colorectal Cancer

Autor: Yong S. Kim, Hyoungseok Ju, Tae W. Kim, Seon A. Roh, Chan W. Kim, Eun Y. Choi, Ye J. Ha, Dong H. Cho, Seon Y. Kim, Jin C. Kim

Purpose: Methods for predicting individual responsiveness to targeted chemotherapy are urgently needed, considering the frequent resistance and extremely high cost.Experimental Design: A chemosensitive single-nucleotide polymorphism (SNP) discovery s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41a587e29c208d9c2c2dddc813d4808d
https://doi.org/10.1158/1078-0432.c.6520304.v1

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Supplementary Figure 2 from Novel Chemosensitive Single-Nucleotide Polymorphism Markers to Targeted Regimens in Metastatic Colorectal Cancer

Autor: Yong S. Kim, Hyoungseok Ju, Tae W. Kim, Seon A. Roh, Chan W. Kim, Eun Y. Choi, Ye J. Ha, Dong H. Cho, Seon Y. Kim, Jin C. Kim

PDF file - 2.6MB, Genome-wide association with in vitro chemosensitivity to targeted regimens: FRB (A), FXB (B), FRC (C), and FXC (D). Association of SNPs with the inhibition ratio was tested by linear regression analysis. P-values of < 0.001 are ind

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45cafa4041221aa1402e52d723d9e475
https://doi.org/10.1158/1078-0432.22444832

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Supplementary Figure 3 from Novel Chemosensitive Single-Nucleotide Polymorphism Markers to Targeted Regimens in Metastatic Colorectal Cancer

Autor: Yong S. Kim, Hyoungseok Ju, Tae W. Kim, Seon A. Roh, Chan W. Kim, Eun Y. Choi, Ye J. Ha, Dong H. Cho, Seon Y. Kim, Jin C. Kim

PDF file - 1.4MB, Cell viability measured by MTT assay in transfected CRC clones (a. DFNB31 rs2274159; b. ANXA11 rs1049550; c. LINS1 rs11247226) treated with FRC (a), FRB (b), and FXB (c), respectively. Bold font, P < 0.05. FRC, FOLFIRI + cetuximab;

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd00e457c27686519a684a341d57439
https://doi.org/10.1158/1078-0432.22444829.v1

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Akademický článek

Opposite functions of GSN and OAS2 on colorectal cancer metastasis, mediating perineural and lymphovascular invasion, respectively.

Autor: Jin Cheon Kim, Ye Jin Ha, Ka Hee Tak, Seon Ae Roh, Yi Hong Kwon, Chan Wook Kim, Yong Sik Yoon, Jong Lyul Lee, Yangsoon Park, Seon-Kyu Kim, Seon-Young Kim, Dong-Hyung Cho, Yong Sung Kim

Publikováno v: PLoS ONE, Vol 13, Iss 8, p e0202856 (2018)

The present study aimed to identify molecules associated with lymphovascular invasion (LVI) and perineural invasion (PNI) and to examine their biological behavior in colorectal cancer (CRC). LVI- and PNI-associated molecules were identified and verif

Externí odkaz: https://doaj.org/article/f1e85061e1cc47c4bf32fa55a2e6afc4

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SLAMF7 and TREM1 Mediate Immunogenic Cell Death in Colorectal Cancer Cells: Focus on Microsatellite Stability

Autor: Seon Ae Roh, Jin Cheon Kim, Yi Hong Kwon, Jong Lyul Lee, Seon-Kyu Kim

Publikováno v: Anticancer Research. 41:5431-5444

BACKGROUND/AIM The aim of this study was to identify the association between SLAMF7 and TREM1 and anti-PD-1 drugs, and to determine whether they are molecular targets or predictors of responses to immunotherapy through induction of immunogenic cell d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67c7d2924293f1eb7d80a7d273a34abf
https://doi.org/10.21873/anticanres.15355

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