Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Seolkyoung Jung"'
Autor:
Estienne C Swart, John R Bracht, Vincent Magrini, Patrick Minx, Xiao Chen, Yi Zhou, Jaspreet S Khurana, Aaron D Goldman, Mariusz Nowacki, Klaas Schotanus, Seolkyoung Jung, Robert S Fulton, Amy Ly, Sean McGrath, Kevin Haub, Jessica L Wiggins, Donna Storton, John C Matese, Lance Parsons, Wei-Jen Chang, Michael S Bowen, Nicholas A Stover, Thomas A Jones, Sean R Eddy, Glenn A Herrick, Thomas G Doak, Richard K Wilson, Elaine R Mardis, Laura F Landweber
Publikováno v:
PLoS Biology, Vol 11, Iss 1, p e1001473 (2013)
The macronuclear genome of the ciliate Oxytricha trifallax displays an extreme and unique eukaryotic genome architecture with extensive genomic variation. During sexual genome development, the expressed, somatic macronuclear genome is whittled down t
Externí odkaz:
https://doaj.org/article/2c997db6921e48499101458b87b25641
Autor:
Trzaskoma, Pawel1 pawel.trzaskoma@nih.gov, SeolKyoung Jung1, Pękowska, Aleksandra1,2, Bohrer, Christopher H.3, Xiang Wang1,4, Naz, Faiza1, Dell'Orso, Stefania1, Dubois, Wendy D.3, Olivera, Ana5, Vartak, Supriya V.1, Yongbing Zhao1, Nayak, Subhashree1, Overmiller, Andrew1, Morasso, Maria I.1, Sartorelli, Vittorio1, Larson, Daniel R.3, Chow, Carson C.6 carsonc@niddk.nih.gov, Casellas, Rafael1, O'Shea, John J.1 osheaj@arb.niams.nih.gov
Publikováno v:
Science Advances. 8/9/2024, Vol. 10 Issue 32, p1-17. 17p.
Autor:
Peter D. Kwong, Jenna Ariel Lieberman, Adam S. Olia, Kai Xu, Paul D. Bieniasz, Zijun Wang, Julio C. C. Lorenzi, Michel C. Nussenzweig, Andrea Conte, Theodora Hatziioannou, Pengfei Wang, Tyler Stephens, Yaoxing Huang, David D. Ho, Vincent J. Munster, Tatsiana Bylund, I-Ting Teng, Rafael Casellas, Frauke Muecksch, Fabian Schmidt, Jianliang Xu, Gwo-Yu Chuang, Solji Park, Yaroslav Tsybovsky, Tongqing Zhou, Manoj S. Nair, Seolkyoung Jung, Jonathan E. Schulz, Lino Tessarollo, Yang Luo
Publikováno v:
Nature. 595(7866)
Since the start of the COVID-19 pandemic, SARS-CoV-2 has caused millions of deaths worldwide. Although a number of vaccines have been deployed, the continual evolution of the receptor-binding domain (RBD) of the virus has challenged their efficacy. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15ec5f6de40a7c375568a3f3596a7490
https://pubmed.ncbi.nlm.nih.gov/34193999
https://pubmed.ncbi.nlm.nih.gov/34193999
Autor:
Liangqi Xie, Peng Dong, Yifeng Qi, Tsung-Han S. Hsieh, Brian P. English, SeolKyoung Jung, Xingqi Chen, Margherita De Marzio, Rafael Casellas, Howard Y. Chang, Bin Zhang, Robert Tjian, Zhe Liu
Publikováno v:
Nature genetics, vol 54, iss 4
Mammalian chromosomes are organized into megabase-sized compartments that are further subdivided into topologically associating domains (TADs). While the formation of TADs is dependent on cohesin, the mechanism behind compartmentalization remains eni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc5b09edc4afaef7d6161e9ef9462039
https://pubmed.ncbi.nlm.nih.gov/35410382
https://pubmed.ncbi.nlm.nih.gov/35410382
Autor:
Solji Park, Kyong-Rim Kieffer-Kwon, Su-Chen Huang, Laila El Khattabi, Francisco J. Asturias, Erez Lieberman Aiden, Suhas S.P. Rao, Haiyan Zhao, Peter Van Blerkom, Jordan Krebs, Xiang Wang, Daniel Chauss, Nathanael Pruett, Subhash K. Tripathi, Marcelo A. Nobrega, Seolkyoung Jung, Philippe Kieffer-Kwon, Erica Sadler, Andrea Lopez, Noboru J. Sakabe, Rafael Casellas, Jens Kalchschmidt, Débora R. Sobreira, Natalie Young
Publikováno v:
Cell. 178(5)
While Mediator plays a key role in eukaryotic transcription, little is known about its mechanism of action. This study combines CRISPR-Cas9 genetic screens, degron assays, Hi-C, and cryoelectron microscopy (cryo-EM) to dissect the function and struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b089073935df12db018b793661a158
https://pubmed.ncbi.nlm.nih.gov/31442397
https://pubmed.ncbi.nlm.nih.gov/31442397
Autor:
Verónica, Delgado-Benito, Daniel B, Rosen, Qiao, Wang, Anna, Gazumyan, Joy A, Pai, Thiago Y, Oliveira, Devakumar, Sundaravinayagam, Wenzhu, Zhang, Matteo, Andreani, Lisa, Keller, Kyong-Rim, Kieffer-Kwon, Aleksandra, Pękowska, Seolkyoung, Jung, Madlen, Driesner, Roman I, Subbotin, Rafael, Casellas, Brian T, Chait, Michel C, Nussenzweig, Michela, Di Virgilio
Publikováno v:
Molecular Cell
Summary Class switch recombination (CSR) is a DNA recombination reaction that diversifies the effector component of antibody responses. CSR is initiated by activation-induced cytidine deaminase (AID), which targets transcriptionally active immunoglob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::650f722620cf10b225e92fc719f07533
https://pubmed.ncbi.nlm.nih.gov/30293785
https://pubmed.ncbi.nlm.nih.gov/30293785
Autor:
Vincent Magrini, Seolkyoung Jung, Laura F. Landweber, Elaine R. Mardis, Patrick Minx, Estienne C. Swart, Sean R. Eddy
Publikováno v:
Nucleic Acids Research
We took advantage of the unusual genomic organization of the ciliate Oxytricha trifallax to screen for eukaryotic non-coding RNA (ncRNA) genes. Ciliates have two types of nuclei: a germ line micronucleus that is usually transcriptionally inactive, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9da619151b7b519967b1d18e30c8e6
https://doi.org/10.1093/nar/gkr501
https://doi.org/10.1093/nar/gkr501
Autor:
Keisuke Nimura, Maria Aurelia Ricci, Evan Stevens, Wolfgang Resch, Brian Glenn St Hilaire, Ying Zheng, Elizabeth H. Finn, Hari Shroff, Peng Dong, Su Chen Huang, Ewy Mathé, Jianliang Xu, Melike Lakadamyali, Rafael Casellas, Tom Misteli, Adriel Casellas, Monique Floer, Diana A. Stavreva, Wendy Dubois, Charles Gregory, Steven M. Johnson, Francesco Tomassoni Ardori, Lino Tessarollo, Steevenson Nelson, Robert D. Phair, Suhas S.P. Rao, Zhe Liu, Kyong-Rim Kieffer-Kwon, Marei Dose, Erez Lieberman Aiden, Eric Batchelor, Michael J. McAndrew, Seolkyoung Jung, Maria Pia Cosma, David Levens, Aleksandra Pekowska, Laura Baranello, Gordon L. Hager
Publikováno v:
Molecular Cell. 67:566-578.e10
50 years ago, Vincent Allfrey and colleagues discovered that lymphocyte activation triggers massive acetylation of chromatin. However, the molecular mechanisms driving epigenetic accessibility are still unknown. We here show that stimulated lymphocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f090fdc9bbf328d8fd5576ffeadd767
https://doi.org/10.1016/j.molcel.2017.07.013
https://doi.org/10.1016/j.molcel.2017.07.013
Autor:
Laura F. Landweber, Vincent Magrini, Yi Zhou, Thomas A. Jones, Klaas Schotanus, John R. Bracht, Sean R. Eddy, Seolkyoung Jung, Elaine R. Mardis, Mariusz Nowacki, Jaspreet S. Khurana, Donna Storton, Jessica L. Wiggins, Kevin Haub, Aaron David Goldman, Glenn Herrick, Michael S. Bowen, Wei-Jen Chang, Richard K. Wilson, Patrick Minx, Xiao Chen, Lance Parsons, Robert S. Fulton, Nicholas A. Stover, John C. Matese, Thomas G. Doak, Estienne C. Swart, Amy Ly, Sean McGrath
Publikováno v:
PLoS Biology
PLoS Biology, Vol 11, Iss 1, p e1001473 (2013)
Swart, Estienne C.; Bracht, John R.; Magrini, Vincent; Minx, Patrick; Chen, Xiao; Zhou, Yi; Khurana, Jaspreet S.; Goldman, Aaron D.; Nowacki, Mariusz; Schotanus, Klaas; Jung, Seolkyoung; Fulton, Robert S.; Ly, Amy; McGrath, Sean; Haub, Kevin; Wiggins, Jessica L.; Storton, Donna; Matese, John C.; Parsons, Lance; Chang, Wei-Jen; ... (2013). The Oxytricha trifallax macronuclear genome: a complex eukaryotic genome with 16,000 tiny chromosomes. PLoS biology, 11(1), e1001473. Public Library of Science 10.1371/journal.pbio.1001473
PLoS Biology, Vol 11, Iss 1, p e1001473 (2013)
Swart, Estienne C.; Bracht, John R.; Magrini, Vincent; Minx, Patrick; Chen, Xiao; Zhou, Yi; Khurana, Jaspreet S.; Goldman, Aaron D.; Nowacki, Mariusz; Schotanus, Klaas; Jung, Seolkyoung; Fulton, Robert S.; Ly, Amy; McGrath, Sean; Haub, Kevin; Wiggins, Jessica L.; Storton, Donna; Matese, John C.; Parsons, Lance; Chang, Wei-Jen; ... (2013). The Oxytricha trifallax macronuclear genome: a complex eukaryotic genome with 16,000 tiny chromosomes. PLoS biology, 11(1), e1001473. Public Library of Science 10.1371/journal.pbio.1001473
With more chromosomes than any other sequenced genome, the macronuclear genome of Oxytricha trifallax has a unique and complex architecture, including alternative fragmentation and predominantly single-gene chromosomes.
The macronuclear genome o
The macronuclear genome o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf977c20f3f916a10d34724c67c644ff
http://europepmc.org/articles/PMC3558436
http://europepmc.org/articles/PMC3558436
Publikováno v:
Genome Biology and Evolution
Programmed genome rearrangements in the unicellular eukaryote Oxytricha trifallax produce a transcriptionally active somatic nucleus from a copy of its germline nucleus during development. This process eliminates noncoding sequences that interrupt co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::664cc3ecb9c7b5b1da76adb53f8030ef
https://doi.org/10.1093/gbe/evv172
https://doi.org/10.1093/gbe/evv172