Zobrazeno 1 - 10 of 28 pro vyhledávání: '"SeolMin Yoon"'
1
Akademický článek
Pyrrolidine-based 3-deoxysphingosylphosphorylcholine analogs as possible candidates against neglected tropical diseases (NTDs): identification of hit compounds towards development of potential treatment of Leishmania donovani
Autor: Ahmed H. E. Hassan, Trong-Nhat Phan, Seolmin Yoon, Cheol Jung Lee, Hye Rim Jeon, Seung-Hwan Kim, Joo Hwan No, Yong Sup Lee
Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1922-1930 (2021)
A rational-based process was adopted for repurposing pyrrolidine-based 3-deoxysphingosylphosphorylcholine analogs bearing variable acyl chains, different stereochemical configuration and/or positional relationships. Structural features were highly in
Externí odkaz: https://doaj.org/article/33781956a9284f9394ef0a3eb388e31d
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3
Akademický článek
Mepirapim, a Novel Synthetic Cannabinoid, Induces Addiction-Related Behaviors through Neurochemical Maladaptation in the Brain of Rodents
Autor: Kwang-Hyun Hur, YouYoung Lee, Audrey Lynn Donio, Shi-Xun Ma, Bo-Ram Lee, Seon-Kyung Kim, Jae-Gyeong Lee, Young-Jung Kim, MinJeong Kim, SeolMin Yoon, SooYeun Lee, Yong-Sup Lee, Seok-Yong Lee, Choon-Gon Jang
Publikováno v: Pharmaceuticals, Vol 15, Iss 6, p 710 (2022)
Mepirapim is a synthetic cannabinoid that has recently been abused for recreational purposes. Although serious side effects have been reported from users, the dangerous pharmacological effects of Mepirapim have not been scientifically demonstrated. I
Externí odkaz: https://doaj.org/article/bc50556167c644cba4219c6b3ab03d0a
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4
Mepirapim, a novel synthetic cannabinoid, induces Parkinson’s disease-related behaviors by causing maladaptation of the dopamine system in the brain
Autor: Kwang-Hyun Hur, Youyoung Lee, Audrey Lynn Donio, Jae-Gyeong Lee, Bo-Ram Lee, Seon-Kyung Kim, Seolmin Yoon, Yong-Sup Lee, Hyoung-Chun Kim, Seok-Yong Lee, Choon-Gon Jang
Publikováno v: Archives of Toxicology. 97:581-591
Mepirapim is a novel synthetic cannabinoid that first appeared on the illicit drug market in 2013. In recent years, recreational abuse of Mepirapim has caused serious emergencies, posing a threat to public health. However, there are no legal regulati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed6086b17c53cd55f137e8394ab0684f
https://doi.org/10.1007/s00204-022-03414-y
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6
Abuse Potential of Synthetic Cannabinoids: AM-1248, CB-13, and PB-22
Autor: Shi-Xun Ma, Hye Jin Kim, Yong-Hyun Ko, Jee-Yeon Seo, Hye Won Ryu, Seok-Yong Lee, Seolmin Yoon, Yong-Sup Lee, Kwang-Hyun Hur, Boram Lee, Choon-Gon Jang
Publikováno v: Biomolecules & Therapeutics
Currently, the expanding recreational use of synthetic cannabinoids (SCBs) threatens public health. SCBs produce psychoactive effects similar to those of tetrahydrocannabinol, the main component of cannabis, and additionally induce unexpected pharmac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82439b9a2ca2468db16857c4e0e78570
https://doi.org/10.4062/biomolther.2020.212
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7
Enantiopure methoxetamine stereoisomers: chiral resolution, conformational analysis, UV-circular dichroism spectroscopy and electronic circular dichroism
Autor: Seung-Hwan Kim, Jae Hoon Cheong, Kun Won Lee, Hye Rim Jeon, Jiyoung Kim, Yong Sup Lee, Suk Woo Chang, Dae Sik Jang, Hee Jin Kim, Seolmin Yoon, Youngdo Jeong, Cheol Jung Lee, Ahmed H.E. Hassan
Publikováno v: New Journal of Chemistry. 45:4354-4364
The chiral molecule, methoxetamine (MXE), demonstrated promising biological effects in management of treatment-resistant depression patients. To satisfy the need for a method capable of providing gram quantities of each enantiopure stereoisomer of MX
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dd89359b8ff616f4ad702af4e21ec1ba
https://doi.org/10.1039/d0nj05192f
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8
Pyrrolidine-based 3-deoxysphingosylphosphorylcholine analogs as possible candidates against neglected tropical diseases (NTDs): identification of hit compounds towards development of potential treatment of Leishmania donovani
Autor: Hye Rim Jeon, Trong-Nhat Phan, Ahmed H.E. Hassan, Seolmin Yoon, Yong Sup Lee, Cheol Jung Lee, Seung-Hwan Kim, Joo Hwan No
Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1922-1930 (2021)
A rational-based process was adopted for repurposing pyrrolidine-based 3-deoxysphingosylphosphorylcholine analogs bearing variable acyl chains, different stereochemical configuration and/or positional relationships. Structural features were highly in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b19cb64eb265e2bfbe864c8accb7402
https://doi.org/10.1080/14756366.2021.1969385
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