Zobrazeno 1 - 10 of 56 pro vyhledávání: '"Seok-kyu Kang"'
1
Akademický článek
Altered neurological and neurobehavioral phenotypes in a mouse model of the recurrent KCNB1-p.R306C voltage-sensor variant
Autor: Seok Kyu Kang, Nicole A. Hawkins, Christopher H. Thompson, Erin M. Baker, Dennis M. Echevarria-Cooper, Levi Barse, Tyler Thenstedt, Conor J. Dixon, Nathan Speakes, Alfred L. George, Jr, Jennifer A. Kearney
Publikováno v: Neurobiology of Disease, Vol 194, Iss , Pp 106470- (2024)
Pathogenic variants in KCNB1 are associated with a neurodevelopmental disorder spectrum that includes global developmental delays, cognitive impairment, abnormal electroencephalogram (EEG) patterns, and epilepsy with variable age of onset and severit
Externí odkaz: https://doaj.org/article/4b98448bbf9f4c469dfa4fe4876231d8
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2
Akademický článek
Weighted Averaging Federated Learning Based on Example Forgetting Events in Label Imbalanced Non-IID
Autor: Mannsoo Hong, Seok-Kyu Kang, Jee-Hyong Lee
Publikováno v: Applied Sciences, Vol 12, Iss 12, p 5806 (2022)
Federated learning, a data privacy-focused distributed learning method, trains a model by aggregating local knowledge from clients. Each client collects and utilizes its own local dataset to train a local model. Local models in the connected federate
Externí odkaz: https://doaj.org/article/63af2735d53942789fba6a15b5b19caa
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3
Akademický článek
Epilepsy and neurobehavioral abnormalities in mice with a dominant-negative KCNB1 pathogenic variant
Autor: Nicole A. Hawkins, Sunita N Misra, Manuel Jurado, Seok Kyu Kang, Nicholas C. Vierra, Kimberly Nguyen, Lisa Wren, Alfred L. George, Jr., James S. Trimmer, Jennifer A. Kearney
Publikováno v: Neurobiology of Disease, Vol 147, Iss , Pp 105141- (2021)
Developmental and epileptic encephalopathies (DEE) are a group of severe epilepsies that usually present with intractable seizures, developmental delay, and often have elevated risk for premature mortality. Numerous genes have been identified as a mo
Externí odkaz: https://doaj.org/article/3a83b62538ec4d4d97854b1d9c5a67df
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5
Akademický článek
Off-Label Use of Bumetanide for Brain Disorders: An Overview
Autor: Shivani C. Kharod, Seok Kyu Kang, Shilpa D. Kadam
Publikováno v: Frontiers in Neuroscience, Vol 13 (2019)
Bumetanide (BTN or BUM) is a FDA-approved potent loop diuretic (LD) that acts by antagonizing sodium-potassium-chloride (Na-K-Cl) cotransporters, NKCC1 (SLc12a2) and NKCC2. While NKCC1 is expressed both in the CNS and in systemic organs, NKCC2 is kid
Externí odkaz: https://doaj.org/article/b20ad0f5689546d5a6366db8f16233c4
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7
Altered neurological and neurobehavioral phenotypes in a mouse model of the recurrentKCNB1-p.R306C voltage-sensor variant
Autor: Seok Kyu Kang, Nicole A. Hawkins, Dennis M. Echevarria-Cooper, Erin M. Baker, Conor J. Dixon, Nathan Speakes, Jennifer A. Kearney
Publikováno v: bioRxiv
Pathogenic variants inKCNB1are associated with a neurodevelopmental disorder spectrum that includes global developmental delays, cognitive impairment, abnormal electroencephalogram (EEG) patterns, and epilepsy with variable age of onset and severity.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aca641a83403d51ff9d09104e881740
https://doi.org/10.1101/2023.03.29.534736
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