Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Seoju Lee"'
Publikováno v:
Human Gene Therapy. 18:286-300
As with certain successful protein drug treatments, the attachment of polyethylene glycol (PEG) molecules to recombinant adenovirus (rAd) can augment their therapeutic potential. Unlike these proteins, the rAd particle has thousands of target sites f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b41012fd74f0fe3e3be69c869115616
https://doi.org/10.1089/hum.2006.172
https://doi.org/10.1089/hum.2006.172
Autor:
Beth Hutchins, Vellekamp Gary J, Suganto Sutjipto, Todd Machemer, Heidrun Engler, Drake LaFace, Elena Brin, Susan Cannon-Carlson, Douglas Cornell, Mark Horn, Marcio Voloch, Thomas Schluep, Van Tsai, Nico van Rooijen, Dan Maneval, Shu Fen Wen, Seoju Lee, Sundari Ravindran
Publikováno v:
Molecular Therapy. 12:254-263
Intravascular administration of recombinant adenovirus (rAd) in cancer patients has been well tolerated. However, dose-limiting hemodynamic responses associated with suppression of cardiac output have been observed at doses of 7.5 x 10(13) particles.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3a5c8f5ba2a07beebcf79024370c4a
https://doi.org/10.1016/j.ymthe.2005.03.007
https://doi.org/10.1016/j.ymthe.2005.03.007
Autor:
Collette Cutler, Marcio Voloch, Susan Cannon-Carlson, Seoju Lee, Yan-Hui Liu, Wylie David C, Birenda N. Pramanik
Publikováno v:
Pharmaceutical Research. 18:1354-1360
Purpose. Pegylation of therapeutic protein usually results in a mixture of monopegylated proteins with differing sites of modification. With rh-interferon-α2A pegylation, we have found that this heterogeneity includes two classes of pegylation site
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f192f23ca503eb54494460d261fb03cc
https://doi.org/10.1023/a:1013006515587
https://doi.org/10.1023/a:1013006515587
Autor:
Stuart Cox, Susan Cannon-Carlson, Sheri Bradshaw, Grace Michael, Wylie David C, Jeffrey Chapman, Ronald Bordens, Brassard Diana L, Marcio Voloch, Constance Cullen, Jeffrey Spond, Marc DeLorenzo, Stephen R. Indelicato, Seoju Lee
Publikováno v:
The Journal of biological chemistry. 280(8)
Therapeutic pegylated interferon-alphas (IFN-alpha) are mixtures of positional isomers that have been monopegylated at specific sites on the core IFN-alpha molecule. The pegylation results in lower in vitro specific activity associated with the core
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a95493b3422b2209a52a781f7aad5a0
https://pubmed.ncbi.nlm.nih.gov/15596441
https://pubmed.ncbi.nlm.nih.gov/15596441
Publikováno v:
Bioorganicmedicinal chemistry. 2(6)
(R)-alpha-Methyl-3-pyridinebutanamine (5) was required as a key intermediate for production of the PAF antagonist [(R)-(E,E)-5-(4-methoxyphenyl)-N-1- methyl-4-(3-pyridinyl)butyl-2,4-decadienamide (1). A method meeting the requirements of technical si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12bbe79b735451acda09c3dad00f5467
https://pubmed.ncbi.nlm.nih.gov/8000861
https://pubmed.ncbi.nlm.nih.gov/8000861
Autor:
Walker, John M., Smales, C. Mark, James, David C., Wylie, David C., Voloch, Marcio, Seoju Lee, Yan-Hui Liu, Cutler, Collette, Larkin, Brittany, Cannon-Carlson, Susan
Publikováno v:
Therapeutic Proteins; 2005, p337-348, 12p
Autor:
Susan Cannon-Carlson, Stephen R. Indelicato, Grace Michael, Jeffrey Chapman, Constance Cullen, Marcio Voloch, Seoju Lee, Jeffrey Spond, Sheri Bradshaw, Wylie David C, Ronald Bordens
Publikováno v:
Hepatology. 38:729-729
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a743dbec70aba37b95d49adb145246f
https://doi.org/10.1016/s0270-9139(03)81226-0
https://doi.org/10.1016/s0270-9139(03)81226-0
Publikováno v:
Human Gene Therapy; Mar2007, Vol. 18 Issue 3, p286-300, 15p
Autor:
Grace, Michael J.1 michael.grace@spcorp.com, Seoju Lee2, Bradshaw, Sheri1, Chapman, Jeffrey1, Spond, Jeffrey1, Cox, Stuart1, DeLorenzo, Marc1, Brassard, Diana3, Wylie, David2, Cannon-Carlson, Susan2, Cullen, Constance1, Indelicato, Stephen1, Voloch, Marcio2, Bordens, Ronald1
Publikováno v:
Journal of Biological Chemistry. 2/25/2005, Vol. 280 Issue 8, p6327-6336. 10p. 2 Charts, 4 Graphs.