Výsledky vyhledávání - "Seo-Yoon Jeong"

Akademický článek

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Antitumor Activity of Amivantamab (JNJ-61186372), an EGFR–MET Bispecific Antibody, in Diverse Models of EGFR Exon 20 Insertion–Driven NSCLC

Autor: A. Roshak, Chae Won Park, Matthew V. Lorenzi, Seong Gu Heo, Min Hee Hong, Mi Ran Yun, Sun Min Lim, Soo-Hwan Lee, Meena Thayu, Kyoung Ho Pyo, Byoung Chul Cho, Seo Yoon Jeong, Hye Ryun Kim, Seok Young Kim, S.M. Lim, J.C. Curtin, Jiyeon Yun, Jae Hwan Kim, Roland Elmar Knoblauch

Publikováno v: Cancer Discovery. 10:1194-1209

EGFR exon 20 insertion driver mutations (Exon20ins) in non–small cell lung cancer (NSCLC) are insensitive to EGFR tyrosine kinase inhibitors (TKI). Amivantamab (JNJ-61186372), a bispecific antibody targeting EGFR–MET, has shown preclinical activi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::46a6d78c9fe5fee0418366e16ac9bba4
https://doi.org/10.1158/2159-8290.cd-20-0116

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Abstract 1106: BRAF and EGFR fusion as a novel mechanism of resistance mechanism to Lazertinib, 3rd- generation EGFR-TKI, in EGFR-mutant NSCLC

Autor: Seo-Yoon Jeong, Jiyeon Yun, San-Duk Yang, Soo-Hwan Lee, Sangbin Lim, Seok-Young Kim, Min Hee Hong, Sun Min Lim, Hye Ryun Kim, Byoung Chul Cho

Publikováno v: Cancer Research. 81:1106-1106

Background: EGFR-TKI is an established first-line therapy for NSCLC with activating EGFR mutations. Osimertinib, third-generation EGFR TKI, was investigated as a first-in-class drug, but lazertinib(YH25448) was also reported as an outstanding drug wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ec294057db97745282c2683e316e3872
https://doi.org/10.1158/1538-7445.am2021-1106

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Akademický článek

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Abstract 5199: JNJ-61186372, an EGFR-cMet bispecific antibody, in EGFR Exon 20 insertion-driven advanced non-small cell lung cancer (NSCLC)

Autor: Matthew V. Lorenzi, Hye Ryun Kim, Meena Thayu, Ji Min Lee, Seo-Yoon Jeong, Jiyeon Yun, Min Hee Hong, Han Na Kang, Jae Hwan Kim, Soo-Hwan Lee, Roland Elmar Knoblauch, Kyoung Ho Pyo, Chae Won Park, J.C. Curtin, Byoung Chul Cho, Seok-Young Kim

Publikováno v: Cancer Research. 80:5199-5199

PURPOSE: Although EGFR exon20 insertion (ex20ins) mutations account for 4~12 % of EGFR mutant NSCLC patients, there is no effective and selectable anticancer drugs targeting ex20ins mutations so far due to various variant mutations in ex20ins mutatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a7066d4fcf6bc29f8587d775a32528a6
https://doi.org/10.1158/1538-7445.am2020-5199

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Abstract 5198: JNJ-61186372, a novel EGFR/c-Met bispecific antibody, exhibits potent antitumor activity in broad-spectrum of acquired resistance to EGFR-TKIs

Autor: Soo-Hwan Lee, Seo-Yoon Jeong, Min Hee Hong, Seok-Young Kim, Hye Ryun Kim, Byoung Chul Cho, Jiyeon Yun, Chae Won Park

Publikováno v: Cancer Research. 80:5198-5198

Background: 1st generation (erlotinib & gefitinib), 2nd generation (afatinib), and 3rd generation (osimertinib) EGFR TKIs have marked efficacy in patient with EGFR-mutant NSCLC. Unfortunately, patients who show T790M (-) mutation after treated with 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bc8d0b7290216ccaab890eada67c6338
https://doi.org/10.1158/1538-7445.am2020-5198

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Effects of Consumer Awareness of Organic Agricultural Products on Repurchase Intention

Autor: Jinhong Lee, Byungoh Lee, Seo， Yoon-Jeong, Yong-Sil Seo

Publikováno v: Journal of Distribution Science. 13:59-67

Purpose – The number of consumers adopting a lifestyle of health and sustainability has recently increased with the rise of trends in...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dc3911d0a91a6dd1da9f92dc5d333240
https://doi.org/10.15722/jds.13.11.201511.59

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