Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Seo Hyun, Yoon"'
Autor:
Jaeseong Oh, Sojeong Yi, Namyi Gu, Dongseong Shin, Kyung-Sang Yu, Seo Hyun Yoon, Joo-Youn Cho, In-Jin Jang
Publikováno v:
Genomics & Informatics, Vol 16, Iss 3, Pp 52-58 (2018)
In this report, we present a case study of how pharmacogenomics and pharmacometabolomics can be useful to characterize safety and pharmacokinetic profiles in early phase new drug development clinical trials. During conducting a first-in-human trial f
Externí odkaz:
https://doaj.org/article/c9749d02326f4c43a99c73c9afd57778
Autor:
Junghoon Shin, Youngil Koh, Seo Hyun Yoon, Joo‐Youn Cho, Dae‐Young Kim, Kyoo‐Hyung Lee, Hyeong‐Joon Kim, Jae‐Sook Ahn, Yeo‐Kyeoung Kim, Jinny Park, Sang‐Kyun Sohn, Joon Ho Moon, Yoo Jin Lee, Seonghae Yoon, Jeong‐Ok Lee, June‐Won Cheong, Kyoung Ha Kim, Sung‐Hyun Kim, Hoon‐Gu Kim, Hawk Kim, Seung‐Hyun Nam, Young Rok Do, Sang‐Gon Park, Seong Kyu Park, Sung Hwa Bae, Hun Ho Song, Dong‐Yeop Shin, Doyeun Oh, Min Kyoung Kim, Chul Won Jung, Seonyang Park, Inho Kim
Publikováno v:
Cancer Medicine, Vol 7, Iss 5, Pp 1814-1823 (2018)
Abstract Although nilotinib has improved efficacy compared to imatinib, suboptimal response and intolerable adverse events (AEs) limit its effectiveness in many patients with chronic myeloid leukemia in chronic phase (CML‐CP). We investigated the 2
Externí odkaz:
https://doaj.org/article/d3afcb08b0d94b2f8771feee46de40c7
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191258 (2018)
The aim of this study was to explore the pharmacokinetic-pharmacodynamic (PK-PD) relationship of metformin on glucose levels after the administration of 250 mg and 1000 mg of metformin in healthy volunteers.A total of 20 healthy male volunteers were
Externí odkaz:
https://doaj.org/article/e85f250225c64176b9da02891eda6fd2
Autor:
Joo Young Na, Kyung Sang Yu, Jangsoo Yoon, Inseung Jeon, Jae Yong Chung, Yewon Choi, Seo Hyun Yoon
Publikováno v:
Clinical Pharmacology in Drug Development. 10:1469-1477
Omeprazole blocks the gastric H+ /K+ adenosine triphosphatase, thus inhibiting gastric acid secretion, and is metabolized by cytochrome P450 (CYP) 2C19. Due to the physiological changes in the elderly, there are different pharmacokinetic consequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e63761683606bf4ec86bca45f65d5b23
https://doi.org/10.1002/cpdd.966
https://doi.org/10.1002/cpdd.966
Autor:
Jaeseong Oh, SeungHwan Lee, Howard Lee, Joo-Youn Cho, Seo Hyun Yoon, In-Jin Jang, Kyung-Sang Yu, Kyoung Soo Lim
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176320 (2017)
Human carboxylesterase 1 (CES1) is a serine esterase that hydrolyses various exogenous and endogenous compounds including oseltamivir, a prodrug used to treat influenza. A novel CES1 c.662A>G single nucleotide polymorphism (SNP) was predicted to decr
Externí odkaz:
https://doaj.org/article/36e4df244a18406cb992db1bcc4e3e3c
Autor:
Joo Youn Cho, Yu Kyung Kwon, Seo Hyun Yoon, In-Jin Jang, Seung-Hwan Lee, Inseung Jeon, Jaeseong Oh, Kyung Sang Yu
Publikováno v:
Drug Design, Development and Therapy. 15:1735-1747
Inseung Jeon,1,* Jaeseong Oh,1,* Yu-Kyung Kwon,2 Seo Hyun Yoon,1 Joo-Youn Cho,1 In-Jin Jang,1 Kyung-Sang Yu,1 SeungHwan Lee1 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e4a30f35849efd626a3e7d1df35b531
https://doi.org/10.2147/dddt.s303772
https://doi.org/10.2147/dddt.s303772
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 58:634-641
Background Amoxicillin/clavulanate is a widely used oral formulation of penicillin combined with a β-lactamase inhibitor. When using amoxicillin/clavulanate in the elderly, the risk of adverse drug reaction may be greater. This study aimed to evalua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad037f1fffa936a1b51426d791f0408d
https://doi.org/10.5414/cp203773
https://doi.org/10.5414/cp203773
Autor:
In-Jin Jang, Kyung Sang Yu, Sang Chun Ji, Andrew Hyoung Jin Kim, Sang In Park, Seo Hyun Yoon, Jae Young Chung, Jaeseong Oh, Seung-Hwan Lee, Sang Won Lee
Publikováno v:
The Pharmacogenomics Journal. 20:792-800
High pharmacokinetic variability of voriconazole is mainly explained by CYP2C19 phenotype, but there are still unknown factors affecting the variability. In this study, the effect of solute carrier organic anion transporter family member 2B1 (SLCO2B1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3501439795369a0622df301895dc8e91
https://doi.org/10.1038/s41397-020-0166-1
https://doi.org/10.1038/s41397-020-0166-1
Publikováno v:
International journal of clinical pharmacology and therapeutics. 59(10)
Objective Theracurmin is a submicron dispersed formulation of curcumin, which was developed to increase the bioavailability of curcumin. This study aimed to compare the pharmacokinetics of curcumin administered as two Theracurmin powder products and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da852e998ba62b0472975820ec5df72
https://pubmed.ncbi.nlm.nih.gov/34423771
https://pubmed.ncbi.nlm.nih.gov/34423771
Autor:
Hye Ryun Kang, Dong Yoon Kang, Ju Young Kim, Woo-Kon Lee, Young Hun Choi, Sang Heon Cho, Suh Young Lee, Seo Hyun Yoon
Publikováno v:
Journal of Investigational Allergology and Clinical Immunology. 29:444-450
OBJECTIVES We investigated the incidence of immediate hypersensitivity reaction (HSR) caused by different types of low-osmolar contrast media (LOCM) and cumulative exposure to LOCM. METHODS This cohort study included all consecutive patients who unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cea8458be92f2faa61de322d2242b34
https://doi.org/10.18176/jiaci.0374
https://doi.org/10.18176/jiaci.0374