Výsledky vyhledávání - "Seo, Young Woo"

Akademický článek

A phosphodiesterase 4 (PDE4) inhibitor, amlexanox, reduces neuroinflammation and neuronal death after pilocarpine-induced seizure

Autor: Hyun Wook Yang, A Ra Kho, Song Hee Lee, Beom Seok Kang, Min Kyu Park, Chang Jun Lee, Se Wan Park, Seo Young Woo, Dong Yeon Kim, Hyun Ho Jung, Bo Young Choi, Won Il Yang, Hong Ki Song, Hui Chul Choi, Jin Kyu Park, Sang Won Suh

Publikováno v: Neurotherapeutics, Vol 21, Iss 4, Pp e00357- (2024)

Epilepsy, a complex neurological disorder, is characterized by recurrent seizures caused by aberrant electrical activity in the brain. Central to this study is the role of lysosomal dysfunction in epilepsy, which can lead to the accumulation of toxic

Externí odkaz: https://doaj.org/article/a9f0018ab498475d8a8c35ffaa7e19ff

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Akademický článek

Effects of L-Type Voltage-Gated Calcium Channel (LTCC) Inhibition on Hippocampal Neuronal Death after Pilocarpine-Induced Seizure

Autor: Chang-Jun Lee, Song-Hee Lee, Beom-Seok Kang, Min-Kyu Park, Hyun-Wook Yang, Seo-Young Woo, Se-Wan Park, Dong-Yeon Kim, Hyun-Ho Jeong, Won-Il Yang, A-Ra Kho, Bo-Young Choi, Hong-Ki Song, Hui-Chul Choi, Yeo-Jin Kim, Sang-Won Suh

Publikováno v: Antioxidants, Vol 13, Iss 4, p 389 (2024)

Epilepsy, marked by abnormal and excessive brain neuronal activity, is linked to the activation of L-type voltage-gated calcium channels (LTCCs) in neuronal membranes. LTCCs facilitate the entry of calcium (Ca2+) and other metal ions, such as zinc (Z

Externí odkaz: https://doaj.org/article/386f31a91c0540829d837c09e81344ce

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Akademický článek

Effects of Pyruvate Kinase M2 (PKM2) Gene Deletion on Astrocyte-Specific Glycolysis and Global Cerebral Ischemia-Induced Neuronal Death

Autor: Beom-Seok Kang, Bo-Young Choi, A-Ra Kho, Song-Hee Lee, Dae-Ki Hong, Min-Kyu Park, Si-Hyun Lee, Chang-Juhn Lee, Hyeun-Wook Yang, Seo-Young Woo, Se-Wan Park, Dong-Yeon Kim, Jae-Bong Park, Won-Suk Chung, Sang-Won Suh

Publikováno v: Antioxidants, Vol 12, Iss 2, p 491 (2023)

Ischemic stroke is caused by insufficient blood flow to the brain. Astrocytes have a role in bidirectionally converting pyruvate, generated via glycolysis, into lactate and then supplying it to neurons through astrocyte–neuron lactate shuttle (ANLS

Externí odkaz: https://doaj.org/article/7f8a85d289014eb3965be6d2c7abed8f

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