Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Senyan Liu"'
Publikováno v:
The Journal of Clinical Hypertension, Vol 25, Iss 1, Pp 71-77 (2023)
Abstract Sympathetic activation contributes to the progression of hypertension and chronic kidney disease (CKD). Ablation of renal sympathetic nerves lowers blood pressure (BP) and preserves renal function in patients with CKD and uncontrolled hypert
Externí odkaz:
https://doaj.org/article/83b2892537a247a9a135b619c0f92881
Publikováno v:
The Journal of Clinical Hypertension. 25:71-77
Sympathetic activation contributes to the progression of hypertension and chronic kidney disease (CKD). Ablation of renal sympathetic nerves lowers blood pressure (BP) and preserves renal function in patients with CKD and uncontrolled hypertension by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a3fee8ca74c4e3040bbf5ac2ba763a4
https://doi.org/10.1111/jch.14605
https://doi.org/10.1111/jch.14605
Autor:
Senyan Liu, Stewart Sell, Lei Li, Kathleen G. Dickman, Changlin Mei, Xinxin Ding, Xiaochen Bao, Liang Ding, Jun Gu, Qing Yu Zhang
Publikováno v:
Toxicol Sci
The effect of variations in the expression of cytochrome P450 reductase (CPR or POR) is determined in mice with decreased POR expression to identify potential vulnerabilities in people with low POR expression. There is an age-dependent appearance of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff8eb054b45ca0441286bf0a0d490ac3
https://doi.org/10.1093/toxsci/kfz225
https://doi.org/10.1093/toxsci/kfz225
Publikováno v:
Toxicology and Applied Pharmacology. 272:230-237
The kidney is a primary target for numerous toxic compounds. Cytochrome P450 enzymes (P450) are responsible for the metabolic activation of various chemical compounds, and in the kidney are predominantly expressed in proximal tubules. The aim of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81409fd30adb004eefeaa23ed399630
https://doi.org/10.1016/j.taap.2013.05.022
https://doi.org/10.1016/j.taap.2013.05.022
Publikováno v:
Neuroscience Letters. 548:84-89
The aim of this study was to determine the role of NADPH-cytochrome P450 reductase (CPR) and CPR-dependent enzymes in neural stem cell (NSC) genesis in the brain. A mouse model with globally suppressed Cpr gene expression (Cpr-low mouse) was studied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e43e675b4d96151c9ca935d686aa6a5
https://doi.org/10.1016/j.neulet.2013.05.043
https://doi.org/10.1016/j.neulet.2013.05.043
Autor:
Qing Yu Zhang, Senyan Liu, Kathleen G. Dickman, Xinxin Ding, Jun Gu, Lei Li, Stewart Sells, Changlin Mei
Publikováno v:
The FASEB Journal. 29
Cytochrome P450 reductase (CPR or POR) is an obligatory redox partner for all microsomal P450 enzymes. A large, global decrease in POR expression, in a Cpr-low mouse model, was previously found to ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::694f800a548932652055b0c2add9444b
https://doi.org/10.1096/fasebj.29.1_supplement.938.1
https://doi.org/10.1096/fasebj.29.1_supplement.938.1
Autor:
Y W Zhang, Dong Chen, Xiao-Mei Li, Qiang Huang, Senyan Liu, Wanzhong Zou, Hai-chang Huang, Huiying Zhao, Suxia Wang, Y H Li
Publikováno v:
Molecular and Cellular Biochemistry. 284:9-17
Tissue transglutaminase (tTG) is a Ca(2+)-dependent enzyme which stabilizes the extracellular matrix (ECM) through post-translational modification, and may play an important role in the pathogenesis of focal and segmental glomerulosclerosis (FSGS). H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d89fda0196cca99061e7e9d9826a8d
https://doi.org/10.1007/s11010-005-9005-6
https://doi.org/10.1007/s11010-005-9005-6
Autor:
Haiyan Wang, Xiaomei Li, Yan Liang, Haichang Huang, Jingzi Li, Lizhu Wang, Senyan Liu, Yongqiang Li
Publikováno v:
Cellular Physiology and Biochemistry. 16:207-216
The unregulated synthesis of glomerular basement membrane (GBM) components, extracelluar matrix (ECM) proteins, or the secretion of ECM-degradation enzymes, matrix metalloproteinases (MMPs), by podocytes under pathological conditions might be major f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7272bc5febeda91e087cfb9bb5e2a986
https://doi.org/10.1159/000089846
https://doi.org/10.1159/000089846
Autor:
Yingwei, Zhang, Shikai, Yan, Xiang, Gao, Weixing, Dai, Senyan, Liu, Huizi, Jin, Weidong, Zhang, Changlin, Mei
Publikováno v:
Aging clinical and experimental research. 24(5)
A liquid chromatography coupled with mass spectrometry based metabonomics approach was applied to investigate the protective effects of rosiglitazone (RGTZ) and caloric restriction (CR) for renal senescence in a rat model.Kidney tissues and serum sam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7c0a9edbf144b6d58789da47cb8ce521
https://pubmed.ncbi.nlm.nih.gov/22572705
https://pubmed.ncbi.nlm.nih.gov/22572705
Autor:
Tao Cheng, Yang Lin, Xinxin Ding, Yunyi Yao, Lihua Wang, Jun Gu, Dongsheng Xiong, Bhagavatula Moorthy, Senyan Liu
Publikováno v:
Toxicology letters. 212(2)
Microsomal cytochrome P450 (P450) enzymes, which are important in the metabolism of carcinogens, are expressed in both epithelial and stromal cells in the mammary gland. The aim of this study was to investigate the roles of mammary epithelial P450 en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a101d44bfc07de49050c686a783cd7f
https://pubmed.ncbi.nlm.nih.gov/22595614
https://pubmed.ncbi.nlm.nih.gov/22595614