Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Senya Matsufuji"'
Publikováno v:
Pharmacology Research & Perspectives, Vol 8, Iss 3, Pp n/a-n/a (2020)
Abstract Among any drugs, no comparative pharmacological study on how prodrug and its active metabolite behave in animal bodies is available. Immunohistochemistry (IHCs) using newly prepared two monoclonal antibodies, AOS‐96 and AOC‐160, monospec
Externí odkaz:
https://doaj.org/article/00ad40df4c564055b55bd1cbb159f94e
Autor:
Kodai Machida, Senya Matsufuji, Tomoaki Suzuki, Hiroaki Imataka, Takeo Iwamoto, Tomoaki Shigeta, Akihiro Oguro
Publikováno v:
The Journal of Biochemistry. 168:139-149
Antizyme (AZ) interacts with ornithine decarboxylase, which catalyzes the first step of polyamine biosynthesis and recruits it to the proteasome for degradation. Synthesizing the functional AZ protein requires transition of the reading frame at the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101e7da79a8893b99506d3a7a26fd631
https://doi.org/10.1093/jb/mvaa032
https://doi.org/10.1093/jb/mvaa032
Publikováno v:
Pharmacology Research & Perspectives, Vol 8, Iss 3, Pp n/a-n/a (2020)
Pharmacology Research & Perspectives
Pharmacology Research & Perspectives
Among any drugs, no comparative pharmacological study on how prodrug and its active metabolite behave in animal bodies is available. Immunohistochemistry (IHCs) using newly prepared two monoclonal antibodies, AOS‐96 and AOC‐160, monospecific for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29be233cdb8856213b4e92e2de5a6b4c
https://doaj.org/article/00ad40df4c564055b55bd1cbb159f94e
https://doaj.org/article/00ad40df4c564055b55bd1cbb159f94e
Autor:
Noriyuki Murai, Kazutoshi Yoshitake, Takahisa Furukawa, Senya Matsufuji, Zenichi Matsui, Hiroyuki Satoh, Tsuyoshi Takamura, Hiroyuki Kubo, Takashi Yokoo, Takeshi Iwata, Yoshihiro Omori, Satoshi Katagiri, Takaaki Hayashi, Tadashi Nakano
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Scientific Reports
Senior Løken syndrome (SLS) is a heterogeneous disorder characterized by severe retinal degenerations and juvenile-onset nephronophthisis. Genetic variants in ten different genes have been reported as the causes of SLS. Clinical evaluation of a pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf5f7ec4f72d22a5d74f59cc13fc846
http://link.springer.com/article/10.1038/s41598-018-35152-6
http://link.springer.com/article/10.1038/s41598-018-35152-6
Autor:
Koichi Kawamoto, Noriko Goto, Senya Matsufuji, Masamitsu Konno, Kazuhiko Hayashi, Keisuke Tamari, Yuichiro Doki, Kazuhiko Ogawa, Hideshi Ishii, Shinji Tanaka, Masaki Mori, Fumiaki Isohashi, Jun Koseki, Taroh Satoh, Noriyuki Murai, Ayumu Asai
Publikováno v:
Cell Death Discovery, Vol 4, Iss 1, Pp 1-9 (2018)
Cell Death Discovery
Cell Death Discovery
Cancer stem cells (CSCs) exhibit tumorigenic potential and can generate resistance to chemotherapy and radiotherapy. A labeled ornithine decarboxylase (ODC, a rate-limiting enzyme involved in polyamine [PA] biosynthesis) degradation motif (degron) sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::432557b0ee61b26a2518213544516220
http://link.springer.com/article/10.1038/s41420-018-0117-7
http://link.springer.com/article/10.1038/s41420-018-0117-7
Autor:
Noriyuki Murai, Ayasa Tajima, Takeo Iwamoto, Toshiro Migita, Senya Matsufuji, Yasuko Murakami
Publikováno v:
Biochemical and Biophysical Research Communications. 471:646-651
Antizyme (AZ) regulates cellular polyamines (i.e., putrescine, spermidine, and spermine) through binding to ornithine decarboxylase and subsequent ubiquitin-independent degradation of the enzyme protein by the 26S proteasome. Screening for AZ-binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd148c05922358a72bee24591fdadfd
https://doi.org/10.1016/j.bbrc.2016.02.084
https://doi.org/10.1016/j.bbrc.2016.02.084
Autor:
Yutaro Yamamoto, Hironobu Ihn, Hideo Kudo, Yasuko Murakami, Masashi Shin, Kunio Fujiwara, Takamitsu Makino, Senya Matsufuji
Publikováno v:
Histochemistry and cell biology. 149(2)
No expression and distribution patterns of polyamines (PAs), spermine, spermidine, and their precursor putrescine in mammalian hair follicle are available, although polyamines are known to correlate well with hair growth and epidermal tumor genesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1848d43f144f6c7f520b9022defcdae2
https://pubmed.ncbi.nlm.nih.gov/29159700
https://pubmed.ncbi.nlm.nih.gov/29159700
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
The proto-oncogene c-Myc encodes a short-lived protein c-Myc that regulates various cellular processes including cell growth, differentiation and apoptosis. Degradation of c-Myc is catalyzed by the proteasome and requires phosphorylation of Thr-58 fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f77ac022377a230e7e0c153545d3baa0
https://pubmed.ncbi.nlm.nih.gov/29445227
https://pubmed.ncbi.nlm.nih.gov/29445227
Publikováno v:
Amino Acids. 46:575-583
Antizyme inhibitor 1 (Azin1), a positive regulator of cellular polyamines, is induced by various proliferative stimuli and repressed by polyamines. It has been reported that the translational repression of Azin1 by polyamines involves an upstream ope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97e397d32d16dc5fb03e0dd3a970b589
https://doi.org/10.1007/s00726-013-1598-6
https://doi.org/10.1007/s00726-013-1598-6
Autor:
Jun Kinoshita, Junko Takahashi-Fujigasaki, Rina Okada, Sho Ishizawa, Yasushi Kanazawa, Tamotsu Yokota, Masami Tsukamoto, Noriyuki Murai, Keiichiro Matoba, Daiji Kawanami, Senya Matsufuji, Kazunori Utsunomiya, Tomoko Ito
Publikováno v:
Kidney International. 84:545-554
The small GTPase Rho and its effector Rho-kinase are involved in the pathogenesis of diabetic nephropathy. Accumulating evidence shows that hypoxia-inducible factor-1α (HIF-1α) is a key regulator of renal sclerosis under diabetic conditions. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac612386d09c146f2c60ae2c09b2db80
https://doi.org/10.1038/ki.2013.130
https://doi.org/10.1038/ki.2013.130