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Autor:
Patrick McCarren, Partha P. Nag, Robert Jedrzejczak, Anne E. Clatworthy, Stewart L. Fisher, Stephen Johnston, Karolina Michalska, Noman Siddiqi, Besnik Bajrami, Stuart L. Schreiber, Andrzej Joachimiak, Samantha Wellington, Natalia Maltseva, Deborah T. Hung, Senya Combs, Virendar K. Kaushik
Publikováno v:
Nature Chemical Biology. 13:943-950
New antibiotics with novel targets are greatly needed. Bacteria have numerous essential functions, but only a small fraction of such processes-primarily those involved in macromolecular synthesis-are inhibited by current drugs. Targeting metabolic en