Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Senthilkumar Sadhasivam"'
Autor:
Uppala Radhakrishna, Rupa Radhakrishnan, Lavanya V. Uppala, Srinivas B. Muvvala, Jignesh Prajapati, Rakesh M. Rawal, Ray O. Bahado-Singh, Senthilkumar Sadhasivam
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
BackgroundNeonatal Opioid Withdrawal Syndrome (NOWS) is a consequence of in-utero exposure to prenatal maternal opioids, resulting in the manifestation of symptoms like irritability, feeding problems, tremors, and withdrawal signs. Opioid use disorde
Externí odkaz:
https://doaj.org/article/0d6254b7eb4640eb8e65161d5031121a
Autor:
Uppala Radhakrishna, Senthilkumar Sadhasivam, Rupa Radhakrishnan, Ariadna Forray, Srinivas B. Muvvala, Raghu P. Metpally, Saumya Patel, Rakesh M. Rawal, Sangeetha Vishweswaraiah, Ray O. Bahado-Singh, Swapan K. Nath
Publikováno v:
Frontiers in Genetics, Vol 14 (2024)
Background: Neonatal opioid withdrawal syndrome (NOWS), arises due to increased opioid use during pregnancy. Cytochrome P450 (CYP) enzymes play a pivotal role in metabolizing a wide range of substances in the human body, including opioids, other drug
Externí odkaz:
https://doaj.org/article/4dbab8a847cb42749fcafff78c1a1426
Autor:
Maitreyi Raman, Ramana Vishnubhotla, Hena R. Ramay, Maria C. B. Gonçalves, Andrea S. Shin, Dhanashri Pawale, Balachundhar Subramaniam, Senthilkumar Sadhasivam
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background Growing evidence suggests a role for gut bacteria and their metabolites in host-signaling responses along the gut-brain axis which may impact mental health. Meditation is increasingly utilized to combat stress, anxiety, and depres
Externí odkaz:
https://doaj.org/article/94ee5d551df946e7b4e9a2e2df40bdef
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 9, p 2611 (2024)
Introduction: In the context of the current opioid crisis, non-pharmacologic approaches to pain management have been considered important alternatives to the use of opioids or analgesics. Advancements in nano and quantum technology have led to the de
Externí odkaz:
https://doaj.org/article/99dce07da6c549d3b4e40178ff94e788
Publikováno v:
Children, Vol 11, Iss 4, p 493 (2024)
There is an anecdotal impression that teenage patients report exaggerated postoperative pain scores that do not correlate with their actual level of pain. Nurse and parental perception of teenagers’ pain can be complemented by knowledge of patient
Externí odkaz:
https://doaj.org/article/36f34f7dfcc24283813202eaf1d1ed84
Autor:
Matthew Kocher, Maria Evankovich, Danielle R. Lavage, Sabri Yilmaz, Senthilkumar Sadhasivam, Mihaela Visoiu
Publikováno v:
Children, Vol 11, Iss 3, p 368 (2024)
Vascular anomalies are a diverse group of abnormal blood vessel developments that can occur at birth or shortly afterward. Embolization and sclerotherapy have been utilized as a treatment option for these malformations but may cause moderate-to-sever
Externí odkaz:
https://doaj.org/article/5830e4d96cdc41b89d810a46742fd3b0
Autor:
Jacques E. Chelly, Brian A. Klatt, Yram Groff, Michael O’Malley, Hsing-Hua Sylvia Lin, Senthilkumar Sadhasivam
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 23, p 7394 (2023)
Background: The potential effectiveness of the non-pharmacological and nanotechnology-based NeuroCuple™ device in reducing postoperative surgical pain and opioid consumption remains unknown. Methods: This randomized controlled open-label study was
Externí odkaz:
https://doaj.org/article/b6e7ee60ea1c453b8afcbb3b8b3a4804
Autor:
Blessed W. Aruldhas, Sara K. Quinney, Brian R. Overholser, Michael A. Heathman, Andrea R. Masters, Reynold C. Ly, Hongyu Gao, Senthil Packiasabapathy, Senthilkumar Sadhasivam
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 10, Pp 1183-1194 (2021)
Abstract Methadone is a synthetic opioid used as an analgesic and for the treatment of opioid abuse disorder. The analgesic dose in the pediatric population is not well‐defined. The pharmacokinetics (PKs) of methadone is highly variable due to the
Externí odkaz:
https://doaj.org/article/a2dc0c6bf16a46479c6de8ed638d0c6b
Autor:
Ramana V. Vishnubhotla, Yi Zhao, Qiuting Wen, Jonathan Dietrich, Gregory M. Sokol, Senthilkumar Sadhasivam, Rupa Radhakrishnan
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
IntroductionInfants with prenatal opioid exposure (POE) are shown to be at risk for poor long-term neurobehavioral and cognitive outcomes. Early detection of brain developmental alterations on neuroimaging could help in understanding the effect of op
Externí odkaz:
https://doaj.org/article/a833cb1c77324978a8f672bfa6233529
Autor:
Sepideh Hariri, Ramana V. Vishnubhotla, Preeti Upadhyay Reed, Akila Rayapuraju, Hibiki Orui, Pavitra Balachundhar, Senthilkumar Sadhasivam, Balachundhar Subramaniam
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
IntroductionAnxiety and depression have increased dramatically 2–3-fold with the COVID-19 pandemic. There is an urgent need for safe, cost-effective, and scalable approaches to alleviate this parallel mental health pandemic. Meditation has previous
Externí odkaz:
https://doaj.org/article/d2b21337729b4ad499f6715d908cd45c