Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Senthil, Selvaraj"'
Autor:
Idris Mohammed, Senthil Selvaraj, Wesam S. Ahmed, Tara Al-Barazenji, Ayat S Hammad, Hajar Dauleh, Luis R. Saraiva, Mashael Al-Shafai, Khalid Hussain
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16361 (2023)
The leptin–melanocortin pathway is pivotal in appetite and energy homeostasis. Pathogenic variants in genes involved in this pathway lead to severe early-onset monogenic obesity (MO). The MC4R gene plays a central role in leptin–melanocortin sign
Externí odkaz:
https://doaj.org/article/cfec28209f40430798c9a49b91d9db91
Autor:
Puthen Veettil Jithesh, Mohammed Abuhaliqa, Najeeb Syed, Ikhlak Ahmed, Mohammed El Anbari, Kholoud Bastaki, Shimaa Sherif, Umm-Kulthum Umlai, Zainab Jan, Geethanjali Gandhi, Chidambaram Manickam, Senthil Selvaraj, Chinnu George, Dhinoth Bangarusamy, Rania Abdel-latif, Mashael Al-Shafai, Zohreh Tatari-Calderone, Xavier Estivill, Munir Pirmohamed, The Qatar Genome Program Research Consortium
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-11 (2022)
Abstract Clinical implementation of pharmacogenomics will help in personalizing drug prescriptions and alleviate the personal and financial burden due to inefficacy and adverse reactions to drugs. However, such implementation is lagging in many parts
Externí odkaz:
https://doaj.org/article/c314b59c9cbb499c9aff4aa493e6fdd4
Autor:
Senthil Selvaraj, Deepak L. Bhatt, Ph. Gabriel Steg, Michael Miller, Eliot A. Brinton, Terry A. Jacobson, Rebecca A. Juliano, Lixia Jiao, Jean‐Claude Tardif, Christie M. Ballantyne
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 7 (2022)
Background Patients with heart failure (HF) are at high risk for atherosclerotic cardiovascular disease. Studies of atherothrombotic treatments in this population have been disappointing to date. Icosapent ethyl reduced the risk of atherosclerotic ca
Externí odkaz:
https://doaj.org/article/6a510abbc1e94e089d893b3483643e94
Autor:
Senthil Selvaraj, Brian L. Claggett, Milton Packer, Faiez Zannad, Inder S. Anand, Burkert Pieske, Ziqiang Zhao, Victor C. Shi, Martin P. Lefkowitz, John J. V. McMurray, Scott D. Solomon
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 17 (2021)
Background Dyslipidemia is common in heart failure with preserved ejection fraction. Sacubitril/valsartan improves glycemic control and augments natriuretic peptide signaling, providing mechanisms by which sacubitril/valsartan may affect serum lipids
Externí odkaz:
https://doaj.org/article/41949ccd43d34b17bf0daa966bc70bc2
Autor:
Kholoud N. Al‐Shafai, Mohammed Al‐Hashemi, Chidambaram Manickam, Rania Musa, Senthil Selvaraj, Najeeb Syed, Fazulur Vempalli, Muneera Ali, Magdi Yacoub, Xavier Estivill
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 9, Iss 7, Pp n/a-n/a (2021)
Abstract Background Hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) are serious inherited heart diseases with various causative mutations identified. The full spectrum of causative mutations remains to be discovered, especially in
Externí odkaz:
https://doaj.org/article/53125386f953446a93859046b5f1236f
Autor:
Douglas Jacoby, Alejandro E de Feria, Sheela Krishnan, Senthil Selvaraj, Muhammad Shoaib Khan, Mahesh K Vidula, Philip C Wiener, Chaitanya Rojulpote, Ruth Tamrat, Howard Julien, Harold Litt, Daniel Pryma, Jacob Dubroff, Marie A Guerraty, Paco Bravo
Publikováno v:
Open Heart, Vol 8, Iss 1 (2021)
Objective Visually estimated coronary artery calcium (VECAC) from chest CT or attenuation correction (AC)/CT obtained during positron emission tomography (PET)–myocardial perfusion imaging (MPI) is feasible. Our aim was to determine the prognostic
Externí odkaz:
https://doaj.org/article/93a44a88bbb94491ba1705e724dc8165
Autor:
Senthil, Selvaraj, Zhuxuan, Fu, Philip, Jones, Lydia C, Kwee, Sheryl L, Windsor, Olga, Ilkayeva, Christopher B, Newgard, Kenneth B, Margulies, Mansoor, Husain, Silvio E, Inzucchi, Darren K, McGuire, Bertram, Pitt, Benjamin M, Scirica, David E, Lanfear, Michael E, Nassif, Ali, Javaheri, Robert J, Mentz, Mikhail N, Kosiborod, Svati H, Shah
Publikováno v:
Circulation. 146(11)
Background: Sodium-glucose cotransporter-2 inhibitors are foundational therapy in patients with heart failure with reduced ejection fraction (HFrEF), but underlying mechanisms of benefit are not well defined. We sought to investigate the relationship
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f8b9870ff2acbe19e09e991ae63ed8
https://pubmed.ncbi.nlm.nih.gov/36095068
https://pubmed.ncbi.nlm.nih.gov/36095068
Autor:
Senthil Selvaraj, Stephen J. Greene, Sameed Ahmed M. Khatana, Ashwin S. Nathan, Scott D. Solomon, Deepak L. Bhatt
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 18 (2020)
Externí odkaz:
https://doaj.org/article/f462b022457e4751bd9169712d51170b
Autor:
Chaitanya Rojulpote, Abhijit Bhattaru, Christopher Jean, Sarah L. Adams, Vandan Patel, Mahesh K. Vidula, Senthil Selvaraj, Jacob Dubroff, Eliot Peyster, Caitlin B. Clancy, Karen Patterson, Francis E. Marchlinski, Milton Rossman, Lee Goldberg, Paco E. Bravo
Publikováno v:
JACC: Cardiovascular Imaging. 15:1944-1955
Patients with suspected cardiac sarcoidosis frequently undergo fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed tomography (CT) imaging to assess disease activity at baseline and after treatment initiation.This study investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fffd37b9917984e92b98ca11e7a3e75
https://doi.org/10.1016/j.jcmg.2022.05.015
https://doi.org/10.1016/j.jcmg.2022.05.015
Autor:
Pramod Sukumaran, Viviane Nascimento Da Conceicao, Yuyang Sun, Naseem Ahamad, Luis R Saraiva, Senthil Selvaraj, Brij B Singh
Publikováno v:
Cells, Vol 10, Iss 8, p 2125 (2021)
Calcium (Ca2+) functions as a second messenger that is critical in regulating fundamental physiological functions such as cell growth/development, cell survival, neuronal development and/or the maintenance of cellular functions. The coordination amon
Externí odkaz:
https://doaj.org/article/1b1318b9000e4ef5ba121e4d908adaa2