Zobrazeno 1 - 10
of 226
pro vyhledávání: '"Sensitive cell"'
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Triptolide exhibits superior and broad-spectrum antitumor activity. However, the narrow safety window caused by the toxicity of triptolide limits its clinical applications. Although several characterized targets for triptolide are reported, the assoc
Externí odkaz:
https://doaj.org/article/6330a9d40c08443c8d82c24425a9b204
Autor:
Aleksander Rust, Ciara Doran, Rosalyn Hart, Thomas Binz, Paul Stickings, Dorothea Sesardic, Andrew A. Peden, Bazbek Davletov
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Botulinum neurotoxins (BoNTs) type A and type B are commonly used as biopharmaceutics for neurological diseases, uniquely allowing months-long paralysis of target muscles. Their exquisite neuronal specificity is conferred by a multistep process of bi
Externí odkaz:
https://doaj.org/article/a5d1ff3943c640b299a8d604ee755862
Autor:
Shi-Yong Gao, Yun-Fei Gong, Qiu-Jia Sun, Jing Bai, Long Wang, Zi-Quan Fan, Yu Sun, Yi-Jun Su, Jian Gang, Yu-Bin Ji
Publikováno v:
Molecules, Vol 20, Iss 3, Pp 4290-4306 (2015)
Sauromatum giganteum (Engl.) Cusimano & Hett Tuber are used in Chinese folklore medicine for treatment of neoplasms. However, the claim has not been scientifically validated. The aim of the study is to screen the antitumor bioactive fraction of Sauro
Externí odkaz:
https://doaj.org/article/3d56ddc5584546a19aaf41b696cf48ab
Autor:
Sang-Yoon Lee, Howon Lee, Ji Eun Choi, Jaeho Han, Ae-Ran Choi, Jaeeun Yoo, Hyunhye Kang, Joo Hee Jang, Soo-Jung Lee, Eun-Jee Oh
Publikováno v:
Human Immunology. 82:302-308
Introduction Flow cytometric crossmatch assay (FCXM) is a sensitive cell-based method for evaluating the presence of donor-specific antibodies (DSA) before transplantation. Recently, 96-well tray FCXM protocol (Halifax FCXM) with improved test effici
Publikováno v:
Russian Journal of Bioorganic Chemistry. 47:288-298
The cytotoxicity of isosteviol and its twenty derivatives on three human tumor cell lines (ECA-109, MCF-7 and B16-F10) were evaluated. The results demonstrated that ECA-109 was the most sensitive cell line which was exposed to the compound (VI) with
Publikováno v:
J Digit Imaging
Optic nerve crush in mouse model is widely used for investigating the course following retinal ganglion cell (RGCs) injury. Manual cell counting from β-III tubulin stained microscopic images has been routinely performed to monitor RGCs after an opti
Publikováno v:
Environmental Science and Pollution Research. 27:7145-7155
An increasing number and amount of pharmaceuticals for human and veterinary use currently reach the aquatic environment, and the determination of their effects on aquatic organisms becomes of major importance. The 96-h fish lethal test is one of the
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 7
International Journal of Molecular Sciences, Vol 22, Iss 3741, p 3741 (2021)
Volume 22
Issue 7
International Journal of Molecular Sciences, Vol 22, Iss 3741, p 3741 (2021)
The clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 has revolutionized genome editing by providing a simple and robust means to cleave specific genomic sequences. However, introducing templated changes at the targeted site usua