Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Senol Akay"'
Autor:
Senol Akay, Cristiane França da Silva, Julianna Siciliano de Araújo, Mary K Fisher, Abdelbasset A. Farahat, Moloy Banerjee, Edézio Ferreira Cunha-Júnior, Maria de Nazaré Correia Soeiro, Denise da Gama Jaen Batista, Chad E. Stephens, David W. Boykin
Publikováno v:
Drug Design, Development and Therapy. 11:1095-1105
Arylimidamides (AIAs), previously termed as reversed amidines, present a broad spectrum of activity against intracellular microorganisms. In the present study, three novel AIAs were evaluated in a mouse model of Trypanosoma cruzi infection, which is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::204272ffa19000b6dbaea2b7da8954aa
https://doi.org/10.2147/dddt.s120618
https://doi.org/10.2147/dddt.s120618
Autor:
Cristiane França, da Silva, Denise da Gama Jaén, Batista, Julianna Siciliano, de Araújo, Edézio Ferreira, Cunha-Junior, Chad E, Stephens, Moloy, Banerjee, Abdelbasset A, Farahat, Senol, Akay, Mary K, Fisher, David W, Boykin, Maria de Nazaré Correia, Soeiro
Publikováno v:
Drug Design, Development and Therapy
Arylimidamides (AIAs), previously termed as reversed amidines, present a broad spectrum of activity against intracellular microorganisms. In the present study, three novel AIAs were evaluated in a mouse model of Trypanosoma cruzi infection, which is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9217e09077be2be70c676f8097b1a592
https://pubmed.ncbi.nlm.nih.gov/28435221
https://pubmed.ncbi.nlm.nih.gov/28435221
Autor:
Arvind Kumar, Abdelbasset A. Farahat, Marie-Hélène David-Cordonnier, Moloy Banerjee, Manoj Munde, Sabine Depauw, Nancy H. Campbell, Senol Akay, Zong-ying Liu, Leah Mickelson, Stephen Neidle, Raja Nhili, David W. Boykin, W. David Wilson, Yun Chai, Sen Lin
Publikováno v:
ChemBioChem. 15:68-79
Heterocyclic diamidines are strong DNA minor-groove binders and have excellent antiparasitic activity. To extend the biological activity of these compounds, a series of arylimidamides (AIAs) analogues, which have better uptake properties in Leishmani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a4a8bbdc42d8fdb6f2a69ae203b3668
https://doi.org/10.1002/cbic.201300622
https://doi.org/10.1002/cbic.201300622
Autor:
Laixing Hu, Abdelbasset A. Farahat, Patrícia Bernardino da Silva, David W Boykin, Zong-ying Liu, Anissa Daliry, Moloy Banerjee, Senol Akay, Chad E. Stephens, Cristiane França da Silva, Maria de Nazaré Correia Soeiro, Mary K Fisher, Arvind Kumar
Publikováno v:
Parasitology. 138:1863-1869
SUMMARYThe present study aimed to determine the in vitro biological efficacy and selectivity of 7 novel AIAs upon bloodstream trypomastigotes and intracellular amastigotes of Trypanosoma cruzi. The biological activity of these aromatic compounds was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4674c378dd2ccd6b0649cb4cea1c353
https://doi.org/10.1017/s0031182011001429
https://doi.org/10.1017/s0031182011001429
Publikováno v:
European Journal of Organic Chemistry. 2007:2091-2099
Three new fluorescent probes based on the 4-amino-1,8-naphthalimide structure were synthesized, and their sugar binding properties were studied by using D-fructose, D-glucose and D-sorbitol in 0.1 M phosphate buffer at pH 7.4. All three compounds sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ee3d85aa528cf6727f84f1d85d61477
https://doi.org/10.1002/ejoc.200700008
https://doi.org/10.1002/ejoc.200700008
Autor:
Maria de Nazaré Correia Soeiro, Chad E. Stephens, Arvind Kumar, Abdelbasset A. Farahat, Mohamed A. Ismail, Senol Akay, Zong-ying Liu, S. L. De Castro, Cristiane França da Silva, M. Q. Pires, Manoj Munde, W. D. Wilson, R. S. Pacheco, Anissa Daliry, Qiyue Hu, D. W. Boykin, Peter M. Som
Due to limited efficacy and considerable toxicity, the therapy for Chagas' disease is far from being ideal, and thus new compounds are desirable. Diamidines and related compounds such as arylimidamides have promising trypanocidal activity against Try
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e4b89b3c36110f2f970cbb56ee10b3c
https://europepmc.org/articles/PMC3186963/
https://europepmc.org/articles/PMC3186963/
Publikováno v:
Chemical Biology & Drug Design. :070916035247002
Cell surface glycoproteins have been known to play very important roles in various physiologic and pathologic processes. Small molecule compounds capable of carbohydrate recognition can be very useful for the development of sensing, diagnostic, and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99678395e170efe0fa594de7ad7b7a2a
https://doi.org/10.1111/j.1399-3011.2007.00563.x
https://doi.org/10.1111/j.1399-3011.2007.00563.x