Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Senlin Xu"'
Autor:
Yang Yang, Ruimin Hu, Jun Zheng, Qianmei Wang, Senlin Xu, Zhansong Zhou, Dinglin Zhang, Wenhao Shen
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Chronic pelvic pain syndrome (CPPS) is a typical symptom of chronic prostatitis (CP) in males that may cause abnormal urination, sexual dysfunction, or depression and significantly affect the quality of life of the patient. Curren
Externí odkaz:
https://doaj.org/article/11e2b85b93314e7b839c202b3dc7295a
Autor:
Zhipeng Fang, Mingjie Fan, Dongqiang Yuan, Lihua Jin, Yangmeng Wang, Lili Ding, Senlin Xu, Jui Tu, Eryun Zhang, Xiwei Wu, Zhen Bouman Chen, Wendong Huang
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
A hepatic lncRNA Gm19619, which is repressed by vertical sleeve gastrectomy but upregulated by obesity and fasting, regulates gluconeogenesis and lipid metabolism in mice through Foxo1-G6pc/Pck1 and Lepr signaling pathway respectively.
Externí odkaz:
https://doaj.org/article/6e2e1eb73d054ac9931461455e25e4ca
Autor:
Jiawei Zhang, Yichao Gan, Hongzhi Li, Jie Yin, Xin He, Liming Lin, Senlin Xu, Zhipeng Fang, Byung-wook Kim, Lina Gao, Lili Ding, Eryun Zhang, Xiaoxiao Ma, Junfeng Li, Ling Li, Yang Xu, David Horne, Rongzhen Xu, Hua Yu, Ying Gu, Wendong Huang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
CDK2 can drive the proliferation of cancer cells. Here, the authors screened for a non-ATP competitive inhibitor of the CDK2/cylinA complex and find that Homoharringtonine can disrupt the complex and promote the degradation of CDK2.
Externí odkaz:
https://doaj.org/article/ac83cddd29e447fc91fa01e2387d3f72
Autor:
Mingjie Fan, Yangmeng Wang, Lihua Jin, Zhipeng Fang, Jiangling Peng, Jui Tu, Yanjun Liu, Eryun Zhang, Senlin Xu, Xiaoqian Liu, Yuqing Huo, Zhaoli Sun, Xiaojuan Chao, Wen-Xing Ding, Qingfeng Yan, Wendong Huang
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 809-826 (2022)
Background & Aims: Alcohol-associated liver disease (AALD) is one of the most common causes of liver injury and failure. Limited knowledge of the mechanisms underlying AALD impedes the development of efficacious therapies. Bile acid (BA) signaling wa
Externí odkaz:
https://doaj.org/article/65cf997ee44144089c920bc96045e39f
Autor:
Liangjun Zhang, Haihan Xia, Song Du, Nan Zhao, Xiaoxun Zhang, Qiong Pan, Senlin Xu, Zhicheng He, Zeng Yi, Jin Chai
Publikováno v:
Materials & Design, Vol 222, Iss , Pp 111087- (2022)
Hyperinflammation can lead to tissue injury, organ failure, and even fatalities by overproducing proinflammatory cytokines. The long-term safety and outstanding anti-inflammatory ability of natural products have attracted much attention, but the low
Externí odkaz:
https://doaj.org/article/5b120659dbc34756bb581fdac252d25f
Autor:
Jiangling Peng, Mingjie Fan, Kelly X. Huang, Lina A. Huang, Yangmeng Wang, Runkai Yin, Hanyi Zhao, Senlin Xu, Hongzhi Li, Alon Agua, Jun Xie, David A. Horne, Fouad Kandeel, Wendong Huang, Junfeng Li
Publikováno v:
Molecules, Vol 28, Iss 14, p 5332 (2023)
The regulation of bile acid pathways has become a particularly promising therapeutic strategy for a variety of metabolic disorders, cancers, and diseases. However, the hydrophobicity of bile acids has been an obstacle to clinical efficacy due to off-
Externí odkaz:
https://doaj.org/article/5d86e092c94042d3a25316c086fe541f
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-14 (2021)
Abstract The Myc proto-oncogene family consists of three members, C-MYC, MYCN, and MYCL, which encodes the transcription factor c-Myc (hereafter Myc), N-Myc, and L-Myc, respectively. Myc protein orchestrates diverse physiological processes, including
Externí odkaz:
https://doaj.org/article/b53263a7bd8a45e79bf9541602dd52c8
Publikováno v:
IEEE Access, Vol 9, Pp 3735-3743 (2021)
In the context of big data, data sharing between different institutions can not only reduce the cost of information collection greatly but also benefit for obtaining analysis results effectively and efficiently. Record linkage is the task of locating
Externí odkaz:
https://doaj.org/article/d1df433526d44ae18d7b232493147b5b
Autor:
Hong Wu, Tao Wang, Yiqiang Liu, Xin Li, Senlin Xu, Changtao Wu, Hongbo Zou, Mianfu Cao, Guoxiang Jin, Jinyi Lang, Bin Wang, Baohua Liu, Xiaolin Luo, Chuan Xu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-16 (2020)
Abstract Background The identification of novel targets for recovering sorafenib resistance is pivotal for Hepatocellular carcinoma (HCC) patients. Mitophagy is the programmed degradation of mitochondria, and is likely involved in drug resistance of
Externí odkaz:
https://doaj.org/article/7502d60c10d24f09a3b4be155bd4be68
Autor:
Jingru Li, Jianjie Wang, Yiming Shen, Chenxi Dai, Bihua Chen, Yuanyuan Huang, Senlin Xu, Yi Wu, Yongqin Li
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 19 (2020)
Background Oxygen plays a pivotal role in cardiopulmonary resuscitation (CPR) and postresuscitation intervention for cardiac arrest. However, the optimal method to reoxygenate patients has not been determined. This study investigated the effect of ti
Externí odkaz:
https://doaj.org/article/e54834374d474ed39be14fe4055536c3