Bak and Bcl-xL Participate in Regulating Sensitivity of Solid Tumor Derived Cell Lines to Mcl-1 Inhibitors.

Autor: Senichkin VV; Faculty of Medicine, MV Lomonosov Moscow State University, 119991 Moscow, Russia., Pervushin NV; Faculty of Medicine, MV Lomonosov Moscow State University, 119991 Moscow, Russia., Zamaraev AV; Faculty of Medicine, MV Lomonosov Moscow State University, 119991 Moscow, Russia., Sazonova EV; Faculty of Medicine, MV Lomonosov Moscow State University, 119991 Moscow, Russia., Zuev AP; Faculty of Medicine, MV Lomonosov Moscow State University, 119991 Moscow, Russia., Streletskaia AY; Faculty of Medicine, MV Lomonosov Moscow State University, 119991 Moscow, Russia., Prikazchikova TA; Skolkovo Institute of Science and Technology, 121205 Skolkovo, Russia., Zatsepin TS; Skolkovo Institute of Science and Technology, 121205 Skolkovo, Russia.; Faculty of Chemistry, MV Lomonosov Moscow State University, 119991 Moscow, Russia., Kovaleva OV; NN Blokhin Russian Cancer Research Center, Department of Oncogenes Regulation, 115478 Moscow, Russia., Tchevkina EM; NN Blokhin Russian Cancer Research Center, Department of Oncogenes Regulation, 115478 Moscow, Russia., Zhivotovsky B; Faculty of Medicine, MV Lomonosov Moscow State University, 119991 Moscow, Russia.; Institute of Environmental Medicine, Karolinska Institutet, 17177 Stockholm, Sweden., Kopeina GS; Faculty of Medicine, MV Lomonosov Moscow State University, 119991 Moscow, Russia.

Publikováno v: Cancers [Cancers (Basel)] 2021 Dec 30; Vol. 14 (1). Date of Electronic Publication: 2021 Dec 30.

Nutrient Deprivation Promotes MCL-1 Degradation in an Autophagy-Independent Manner.

Autor: Pervushin NV; Faculty of Basic Medicine, Lomonosov Moscow State University, Moscow, 119192, Russia., Senichkin VV; Faculty of Basic Medicine, Lomonosov Moscow State University, Moscow, 119192, Russia., Kapusta AA; Faculty of Basic Medicine, Lomonosov Moscow State University, Moscow, 119192, Russia., Gorbunova AS; Faculty of Basic Medicine, Lomonosov Moscow State University, Moscow, 119192, Russia., Kaminskyy VO; Institute of Environmental Medicine, Karolinska Institute, Stockholm, 17177, Sweden., Zhivotovsky B; Faculty of Basic Medicine, Lomonosov Moscow State University, Moscow, 119192, Russia.; Institute of Environmental Medicine, Karolinska Institute, Stockholm, 17177, Sweden., Kopeina GS; Faculty of Basic Medicine, Lomonosov Moscow State University, Moscow, 119192, Russia. lirroster@gmail.com.

Publikováno v: Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2020 Oct; Vol. 85 (10), pp. 1235-1244.

Upregulation of Mcl-1S Causes Cell-Cycle Perturbations and DNA Damage Accumulation.

Autor: Streletskaia AY; Faculty of Medicine, MV Lomonosov Moscow State University, Moscow, Russia., Senichkin VV; Faculty of Medicine, MV Lomonosov Moscow State University, Moscow, Russia., Prikazchikova TA; Skolkovo Institute of Science and Technology, Skolkovo, Russia., Zatsepin TS; Faculty of Medicine, MV Lomonosov Moscow State University, Moscow, Russia.; Skolkovo Institute of Science and Technology, Skolkovo, Russia., Zhivotovsky B; Faculty of Medicine, MV Lomonosov Moscow State University, Moscow, Russia.; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Kopeina GS; Faculty of Medicine, MV Lomonosov Moscow State University, Moscow, Russia.

Publikováno v: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2020 Sep 25; Vol. 8, pp. 543066. Date of Electronic Publication: 2020 Sep 25 (Print Publication: 2020).

Mcl-1 as a "barrier" in cancer treatment: Can we target it now?

Autor: Pervushin NV; Faculty of Medicine, MV Lomonosov Moscow State University, Moscow, Russia., Senichkin VV; Faculty of Medicine, MV Lomonosov Moscow State University, Moscow, Russia., Zhivotovsky B; Faculty of Medicine, MV Lomonosov Moscow State University, Moscow, Russia; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. Electronic address: boris.zhivotovsky@ki.se., Kopeina GS; Faculty of Medicine, MV Lomonosov Moscow State University, Moscow, Russia. Electronic address: lirroster@gmail.com.

Publikováno v: International review of cell and molecular biology [Int Rev Cell Mol Biol] 2020; Vol. 351, pp. 23-55. Date of Electronic Publication: 2020 Feb 05.

Modulation of Mcl-1 transcription by serum deprivation sensitizes cancer cells to cisplatin.

Autor: Senichkin VV; Faculty of Basic Medicine, MV Lomonosov Moscow State University, Moscow, Russia., Kopeina GS; Faculty of Basic Medicine, MV Lomonosov Moscow State University, Moscow, Russia., Prokhorova EA; Faculty of Basic Medicine, MV Lomonosov Moscow State University, Moscow, Russia., Zamaraev AV; Faculty of Basic Medicine, MV Lomonosov Moscow State University, Moscow, Russia., Lavrik IN; Faculty of Basic Medicine, MV Lomonosov Moscow State University, Moscow, Russia; Department of Translational Inflammation, Institute of Experimental Internal Medicine, Otto von Guericke University, Magdeburg, Germany., Zhivotovsky B; Faculty of Basic Medicine, MV Lomonosov Moscow State University, Moscow, Russia; Division of Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. Electronic address: Boris.Zhivotovsky@ki.se.

Publikováno v: Biochimica et biophysica acta. General subjects [Biochim Biophys Acta Gen Subj] 2018 Mar; Vol. 1862 (3), pp. 557-566. Date of Electronic Publication: 2017 Dec 02.