Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Sengeziwe Sibeko"'
Publikováno v:
Frontiers in Reproductive Health, Vol 6 (2024)
BackgroundTwo-thirds of people living with human immunodeficiency virus type 1 (HIV-1) infection reside in Sub-Saharan Africa, where there are the highest prevalence and incidence rates of human papillomavirus (HPV) infection. Both infections are sex
Externí odkaz:
https://doaj.org/article/b91610465ceb4a2784c256fb1ad4af57
Autor:
Lynn T Matthews, Sengeziwe Sibeko, Leila E Mansoor, Nonhlanhla Yende-Zuma, David R Bangsberg, Quarraisha Abdool Karim
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e56400 (2013)
Antiretroviral prophylaxis may be a critical strategy to reduce periconception HIV transmission. Maximizing the benefit of periconception pharmacologic HIV risk-reduction requires an understanding of the links between pregnancy and adherence to this
Externí odkaz:
https://doaj.org/article/54438bdedf5141a79858770f365e154e
Autor:
Jo-Ann S. Passmore, Lindi Masson, Lise. Werner, Sengeziwe Sibeko, Lyle R. McKinnon, Koleka Mlisana, Salim S. Abdool Karim, Muki Shey, Quarraisha Abdool Karim, Sinaye Ngcapu, Natasha Samsunder
Publikováno v:
Journal of Reproductive Immunology. 110:14-21
Progesterone-based injectable hormonal contraceptives (HCs) potentially modulate genital barrier integrity and regulate the innate immune environment in the female genital tract, thereby enhancing the risk of STIs or HIV infection. We investigated th
Autor:
Sengeziwe Sibeko, Nomsa Miya, Anneke Grobler, Quarraisha Abdool Karim, Nonhlanhla Yende-Zuma, Salim S. Abdool Karim, David C. Sokal, Cheryl Baxter, Leila E. Mansoor, Koleka Mlisana, Silvia Maarshalk, Janet Frolich, A. Kharsany
Publikováno v:
Antiviral Therapy. 18:301-310
Background Tenofovir gel, used vaginally before and after coitus, reduced women's acquisition of HIV by 39%. This is a safety assessment of tenofovir gel, including renal, bone, gastrointestinal, genital and haematological parameters. Methods In the
Publikováno v:
Best Practice & Research Clinical Obstetrics & Gynaecology. 26:473-486
The distinctive feature of the human immunodeficiency virus (HIV) epidemic in Sub-Saharan Africa is the burden on women, in particular young women of reproductive age. Consequently, most late-phase effectiveness microbicide clinical trials are conduc
Autor:
Raveshni Durgiah, Sengeziwe Sibeko, Marcus Altfeld, Quarraisha Abdool Karim, Natasha Samsunder, Salim S. Abdool Karim, William H. Carr, Vivek Naranbhai
Publikováno v:
The Journal of Infectious Diseases. 206:993-1001
The antiretroviral agent, tenofovir, formulated as a vaginal microbicide gel, reduces human immunodeficiency virus (HIV) acquisition by 39% in women. This study assessed the role of preexisting immune activation in HIV acquisition in women from the C
Autor:
Nthabeleng Ranchobe, Carolyn Williamson, Nancy Tumba, Daniel J. Sheward, Koleka Mlisana, Zhong Lai, Abraham Pinter, Sengeziwe Sibeko, Salim S. Abdool Karim, William J. Honnen, Lynn Morris, Elin S. Gray, Maphuti C. Madiga, Tandile Hermanus, Molati Nonyane, Penny L. Moore
Publikováno v:
Journal of Virology. 85:3128-3141
The targets of broadly cross-neutralizing (BCN) antibodies are of great interest in the HIV vaccine field. We have identified a subtype C HIV-1-superinfected individual, CAP256, with high-level BCN activity, and characterized the antibody specificity
Autor:
Constantinos Kurt Wibmer, Tandile Hermanus, Elin S. Gray, Lise. Werner, Maphuti C. Madiga, Lynn Morris, Penny L. Moore, Sengeziwe Sibeko, Koleka Mlisana, Salim S. Abdool Karim, Nancy Tumba, Carolyn Williamson
Publikováno v:
Journal of Virology
An understanding of how broadly neutralizing activity develops in HIV-1-infected individuals is needed to guide vaccine design and immunization strategies. Here we used a large panel of 44 HIV-1 envelope variants (subtypes A, B, and C) to evaluate th
Autor:
Julia Makinde, Clifford Jones, Angela Bartolf, Sengeziwe Sibeko, Susan Baden, Catherine Cosgrove, Robin J. Shattock
Publikováno v:
American Journal of Reproductive Immunology. 79:e12819
Autor:
Sengeziwe Sibeko, Susan Baden, Clifford Jones, Julia Makinde, Robin J. Shattock, Angela Bartolf, Catherine Cosgrove
Publikováno v:
American Journal of Reproductive Immunology. 79:e12801
PROBLEM: Fluctuating hormones regulate reproductive processes in the female genital tract. Consequent changes in the local immunological environment are likely to affect cellular interaction with infectious agents and the assessment of therapies that