Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Senga K. Oxenham"'
Autor:
Ülo Langel, John Howl, Monika Lukanowska, Julia Suhorutsenko, Sarah Jones, Stephen J. Publicover, Senga K. Oxenham, Christopher L.R. Barratt, Dana-Maria Copolovici
Publikováno v:
Scopus-Elsevier
Do cell penetrating peptides (CPPs) translocate into spermatozoa and, if so, could they be utilized to deliver a much larger protein cargo?Chemically diverse polycationic CPPs rapidly and efficiently translocate into spermatozoa. They exhibit differe
Autor:
Katherine M. Whalley, Christopher L.R. Barratt, Senga K. Oxenham, Sarah Martins da Silva, Stephen J. Publicover, Erica Foster, Vanessa Kay, Wardah Abdullah Alasmari
Publikováno v:
Human Reproduction (Oxford, England)
STUDY QUESTION What is the prevalence of defects in the Ca2+-signalling pathways mediating hyperactivation (calcium influx and store mobilization) among donors and sub-fertile patients and are they functionally significant, i.e. related to fertilizat
Autor:
Sarah Costello, Jennifer Morris, Stephen J. Publicover, Jackson Kirkman-Brown, João Ramalho-Santos, Joao Correia, Christopher L.R. Barratt, Wardah Abdullah Alasmari, Leonor Fernandes, Francesco Michelangeli, Senga K. Oxenham
Publikováno v:
The Journal of Biological Chemistry
Background: Ca2+ signals, elicited by cues from the oocyte and female tract, regulate human sperm behavior. Results: CatSper channel activation (flagellum) and Ca2+ store mobilization (neck) caused similar [Ca2+]i elevation but induced functionally d
Autor:
Senga K. Oxenham, Michael J. Groves, Nicola R. Stanley-Wall, Ronald T. Hay, Ivan Matic, Ellis Jaffray, Christopher L.R. Barratt, Sudhir Tauro
Publikováno v:
Journal of Proteome Research
J Proteome Res
J Proteome Res
Quantitative mass spectrometry-based proteomics is a vital tool in modern life science research. In contrast to the popularity of approaches for relative protein quantitation, the widespread use of absolute quantitation has been hampered by inefficie
Autor:
Christopher L.R. Barratt, Steven A. Mansell, Catherine Beaton, Steve Tardif, Senga K. Oxenham
Publikováno v:
Asian Journal of Andrology. 13:53-58
Sperm dysfunction is the single most common cause of infertility, yet what is remarkable is that, there is no drug a man can take or add to his spermatozoa in vitro to improve fertility. One reason for the lack of progress in this area is that our un
Publikováno v:
Mycologia. 97:576-579
Biomass of the fungal pathogen Botrytis fabae in liquid culture amended with two chemotypes of the essential oil of basil, Ocimum basilicum, was reduced significantly at concentrations of 50 ppm or less. The methyl chavicol chemotype oil increased th
Autor:
Senga K. Oxenham
Publikováno v:
Journal of andrology. 31(5)
Autor:
Patricia T.W. Cohen, Amanda Philp, Senga K. Oxenham, Alan R. Prescott, Cristina Martin-Granados
Publikováno v:
The international journal of biochemistrycell biology. 40(10)
The mechanisms that co-ordinate centrosome maturation and the migration of human cells remain elusive. Protein phosphatase 4 (Ppp4) is a ubiquitous protein serine/threonine phosphatase in eukaryotes that is enriched at centrosomes. HEK293 cells cultu
Autor:
Odete A. B. da Cruz e Silva, Senga K. Oxenham, Nicholas R. Helps, Gareth J. Browne, Patricia T.W. Cohen, Wenjuan Wu, Margarida Fardilha, Edgar F. da Cruz e Silva
Publikováno v:
The Biochemical journal. 402(1)
PP1 (protein phosphatase 1) is a ubiquitously expressed serine/threonine-specific protein phosphatase whose activity towards different substrates appears to be mediated via binding to specific proteins that play critical regulatory and targeting role
Publikováno v:
Journal of Biology
A recent paper in BMC Developmental Biology describes the development of the annulus of the mouse sperm cell, but much remains to be learnt about sperm cells despite their importance in human fertility.