Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Seng-Kee Leong"'
Publikováno v:
Annals of the New York Academy of Sciences. 962:161-181
Whether nitric oxide is cytodestructive or cytoprotective is of obvious clinical importance. The debate on this subject in the past decade has generated much “heat and light”. This paper focuses on the actions of NO on the nervous system and reex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae83a2d05fda4c319a27f84edeba6c0
https://doi.org/10.1111/j.1749-6632.2002.tb04066.x
https://doi.org/10.1111/j.1749-6632.2002.tb04066.x
Publikováno v:
Brain Research. 858:163-166
The pathologic hallmark of Parkinson's disease is the dopaminergic cell death in the substantia nigra (SN). The cause of the cell death is, however, unknown. Even the question on whether the cells die by apoptosis or necrosis has not been answered wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::509e54db8c65ffa7eae46c7f9eb0bc93
https://doi.org/10.1016/s0006-8993(99)02459-2
https://doi.org/10.1016/s0006-8993(99)02459-2
Publikováno v:
Experimental Neurology. 161:472-480
Nitric oxide (NO) may subserve different functions in different central neurons subjected to axotomy. The difference may depend on whether the neurons basally express neuronal nitric oxide synthase (nNOS), a biosynthetic enzyme of NO. This is support
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e22d47c50d9108f12df32727ce25f9a
https://doi.org/10.1006/exnr.1999.7278
https://doi.org/10.1006/exnr.1999.7278
Publikováno v:
Experimental Neurology. 158:192-201
Sodium nitroprusside (SNP) has been used as a donor for nitric oxide (NO) to study the effects of NO on the mammalian cochlea. In the present study, we set out to determine whether NO was the chemical responsible for the ototoxic effects seen after t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::278a0bf30c483126ec97b19368873fcf
https://doi.org/10.1006/exnr.1999.7075
https://doi.org/10.1006/exnr.1999.7075
Publikováno v:
The Anatomical Record. 255:261-270
The ultrastructure of the thymus in the chick (Gallus domesticus) was studied after unilateral vagotomy at survival times of 3, 7 and 10 days. Ultrastructural changes in the ipsilateral thymus were observed in axon boutons as well as in myoid and cys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b452de54220ad57836eaaf895c2588fe
https://doi.org/10.1002/(sici)1097-0185(19990701)255:3<261::aid-ar3>3.0.co
https://doi.org/10.1002/(sici)1097-0185(19990701)255:3<261::aid-ar3>3.0.co
Autor:
Seng Kee Leong
Publikováno v:
Free Radical Research. 31:619-629
This paper reviews the work related to nitric oxide (NO) done by the author and his postgraduates and colleagues in the past 7 years in the National University of Singapore. Our work shows that (i) NADPH-d and NO synthase (NOS) are often but not alwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa3ded6b2bcd70e22c28fd07cc4c51ff
https://doi.org/10.1080/10715769900301191
https://doi.org/10.1080/10715769900301191
Autor:
Seng-Kee Leong
Publikováno v:
Clinical Anatomy. 12:422-426
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8544dfab2ddeaf5a473075361b194f54
https://doi.org/10.1002/(sici)1098-2353(1999)12:6<422::aid-ca4>3.0.co
https://doi.org/10.1002/(sici)1098-2353(1999)12:6<422::aid-ca4>3.0.co
Publikováno v:
Free Radical Research. 31:103-112
Parkinson's disease is characterized by dopaminergic cell death in the substantia nigra. The underlying mechanism is, however, unknown. Though there are increasing lines of evidence showing iron accumulation in the Parkinsonian substantia nigra, it s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f2e30b919390c593c3219a29849ed38
https://doi.org/10.1080/10715769900301611
https://doi.org/10.1080/10715769900301611
Publikováno v:
Brain Research. 808:23-30
In the present study, immunohistochemical stainings for OX-6, OX-42, nitric oxide synthase I and II as well as nitrotyrosine were used to investigate possible correlation among microglial reactivity, nitric oxide synthase upregulation, peroxynitrite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbaf2e9b3a0f175ab4bfa898bf2e4b48
https://doi.org/10.1016/s0006-8993(98)00787-2
https://doi.org/10.1016/s0006-8993(98)00787-2
Publikováno v:
Hearing Research. 114:169-178
Nitric oxide (NO) not only has normal physiological roles like vasodilation and neurotransmission in the living organism, it could also have possible neurodestructive effects under certain pathological conditions. The present study aimed to determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d34e91fbc048c672cba4e4b7876ac9
https://doi.org/10.1016/s0378-5955(97)00159-7
https://doi.org/10.1016/s0378-5955(97)00159-7