Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Seng Kah Ng"'
Publikováno v:
PLoS Genetics, Vol 5, Iss 6, p e1000521 (2009)
Eukaryotic organelles evolve to support the lifestyle of evolutionarily related organisms. In the fungi, filamentous Ascomycetes possess dense-core organelles called Woronin bodies (WBs). These organelles originate from peroxisomes and perform an ada
Externí odkaz:
https://doaj.org/article/b36607e92e8a44eb9405478d1df67ceb
Autor:
Rockfield, Stephanie M., Turnis, Meghan E., Rodriguez-Enriquez, Ricardo, Bathina, Madhavi, Seng Kah Ng, Kurtz, Nathan, Mora, Nathalie Becerra, Pelletier, Stephane, Robinson, Camenzind G., Vogel, Peter, Opferman, Joseph T.
Publikováno v:
Life Science Alliance; Jun2024, Vol. 7 Issue 6, p1-10, 10p
Autor:
Orly Leiva, Alison D. Findlay, Shinobu Matsuura, Vipul C. Chitalia, Hector A. Lucero, Seng Kah Ng, Wolfgang Jarolimek, Katya Ravid, Craig Ivan Turner
Publikováno v:
Int J Hematol
Primary myelofibrosis (PMF) is a chronic myeloproliferative neoplasm (MPN) that usually portends a poor prognosis with limited therapeutic options available. Currently only allogeneic stem cell transplantation is curative in those who are candidates,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6106c3bc6f8f56a4e1b8a78e82cca5a0
https://doi.org/10.1007/s12185-019-02751-6
https://doi.org/10.1007/s12185-019-02751-6
Publikováno v:
Journal of biological methods. 4(3)
In addition to various physiologic roles, emerging evidence strongly points to pathogenic roles of tryptophan and of its metabolites, especially in diseases such as renal failure. Accurate estimation of levels of these metabolites in blood is importa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2bb5a5e6ed663d12d9ffc1f2cd28d67
https://pubmed.ncbi.nlm.nih.gov/29707597
https://pubmed.ncbi.nlm.nih.gov/29707597
Publikováno v:
American journal of hematology. 93(3)
The extracellular matrix (ECM) is a key acellular structure in constant remodeling to provide tissue cohesion and rigidity. Deregulation of the balance between matrix deposition, degradation, and crosslinking results in fibrosis. Bone marrow fibrosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66fcb9e1b2e5542e7a00708cd088c212
https://pubmed.ncbi.nlm.nih.gov/29247535
https://pubmed.ncbi.nlm.nih.gov/29247535
Autor:
Seng Kah Ng, Shinobu Matsuura, Carla Mazzeo, Aikaterini Karagianni, Orly Leiva, Alessandro Malara, Alessandra Balduini, Katya Ravid, Christina Ward Torres, Cristal Reyna Thompson
Publikováno v:
Blood. 134:4205-4205
Excessive accumulation of extracellular matrix (ECM) is a hallmark of bone marrow (BM) milieu in Primary Myelofibrosis (PMF). Myelofibrosis was long regarded as a bystander of disease in PMF. However, as cells have the ability to sense the surroundin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9743ff82c188819708dba82328d234e7
https://doi.org/10.1182/blood-2019-132124
https://doi.org/10.1182/blood-2019-132124
Publikováno v:
The Journal of Cell Biology
Woronin bodies (WBs) are dense-core organelles that are found exclusively in filamentous fungi and that seal the septal pore in response to wounding. These organelles consist of a membrane-bound protein matrix comprised of the HEX protein and, althou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::089a677af82b33eba38a5a2468f11b0c
https://doi.org/10.1083/jcb.200705049
https://doi.org/10.1083/jcb.200705049
Publikováno v:
Blood Cancer Journal
Primary myelofibrosis (PMF) is a myeloproliferative neoplasm that arises from clonal proliferation of hematopoietic stem cells and leads to progressive bone marrow (BM) fibrosis. While cellular mutations involved in the development of PMF have been h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1f5f3c4bfb28b963f32118832914ce
https://doi.org/10.1038/bcj.2017.6
https://doi.org/10.1038/bcj.2017.6
Autor:
Philip G. Haydon, Giovanni Manfredi, Lydie Morel, Hibiki Kawamata, Natalia Diaz, Alexandra Osgood, Haruki Higashimori, Seng Kah Ng, Brittany Sider, Suzanne R. Burstein, Yongjie Yang
Motor neurons are progressively and predominantly degenerated in ALS, which is not only induced by multiple intrinsic pathways but also significantly influenced by the neighboring glial cells. In particular, astrocytes derived from the SOD1 mutant mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1942e6a0890c2a2658f6c5196f526706
https://europepmc.org/articles/PMC3913875/
https://europepmc.org/articles/PMC3913875/
Autor:
Yongjie Yang, Lydie Morel, Seng Kah Ng, Jeffrey D. Rothstein, Melissa R. Regan, Svetlana Vidensky, Christine Esau, Haruki Higashimori
Publikováno v:
The Journal of biological chemistry. 288(10)
Perisynaptic astrocytes express important glutamate transporters, especially excitatory amino acid transporter 2 (EAAT2, rodent analog GLT1) to regulate extracellular glutamate levels and modulate synaptic activation. In this study, we investigated a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8129d7bae7e0bcfbfb6eb67b2157af49
https://pubmed.ncbi.nlm.nih.gov/23364798
https://pubmed.ncbi.nlm.nih.gov/23364798