Zobrazeno 1 - 10
of 603
pro vyhledávání: '"Seng Gee, Lim"'
Autor:
Jinlin Hou, Edward Gane, Rozalina Balabanska, Wenhong Zhang, Jiming Zhang, Tien Huey Lim, Qing Xie, Chau-Ting Yeh, Sheng-Shun Yang, Xieer Liang, Piyawat Komolmit, Apinya Leerapun, Zenghui Xue, Ethan Chen, Yuchen Zhang, Qiaoqiao Xie, Ting-Tsung Chang, Tsung-Hui Hu, Seng Gee Lim, Wan-Long Chuang, Barbara Leggett, Qingyan Bo, Xue Zhou, Miriam Triyatni, Wen Zhang, Man-Fung Yuen
Publikováno v:
Clinical and Molecular Hepatology, Vol 30, Iss 2, Pp 191-205 (2024)
Background/Aims Four-week treatment of linvencorvir (RO7049389) was generally safe and well tolerated, and showed anti-viral activity in chronic hepatitis B (CHB) patients. This study evaluated the efficacy, safety, and pharmacokinetics of 48-week tr
Externí odkaz:
https://doaj.org/article/aeead632d03142ec95bc4b04123f5c17
Autor:
Young-Suk Lim, Henry L.Y. Chan, Sang Hoon Ahn, Wai Kay Seto, Qin Ning, Kosh Agarwal, Harry L.A. Janssen, Calvin Q. Pan, Wan Long Chuang, Namiki Izumi, Scott Fung, Shalimar, Maurizia Brunetto, Aric Josun Hui, Ting-Tsung Chang, Seng Gee Lim, Frida Abramov, John F. Flaherty, Hongyuan Wang, Leland J. Yee, Jia-Horng Kao, Edward Gane, Jinlin Hou, Maria Buti
Publikováno v:
JHEP Reports, Vol 5, Iss 10, Pp 100847- (2023)
Background & Aims: Antiviral therapy may attenuate the risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B (CHB). We aimed to explore how tenofovir alafenamide (TAF) and tenofovir disoproxil fumarate (TDF) affect HCC risk in p
Externí odkaz:
https://doaj.org/article/6fa5ef22c05d4c2b921cc10c1111b3f7
Autor:
Saket Jhajharia, Fritz Lai, Heng Boon Low, Kiren Purushotorman, Bhuvaneshwari D/O Shunmuganathan, Conrad En Zuo Chan, Rachel Hammond, Hans-Jürgen Netter, Qingfeng Chen, Seng Gee Lim, Paul A. MacAry
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-9 (2022)
Abstract Hepatitis B Virus (HBV) is a hepadnavirus that is the principal pathogen underlying viral liver disease in human populations. In this study, we describe the isolation and characterization of a fully human monoclonal antibody for HBV. This Hu
Externí odkaz:
https://doaj.org/article/fb283a36a7c34a808b9658dccca347d5
Autor:
JinlinHou, Gane, Edward, Balabanska, Rozalina, WenhongZhang, Jiming Zhang, Tien Huey Lim, Qing Xie, Chau-Ting Yeh, Sheng-Shun Yang, Xieer Liang, Komolmit, Piyawat, Leerapun, Apinya, Zenghui Xue, Chen, Ethan, Yuchen Zhang, Qiaoqiao Xie, Ting-Tsung Chang, Tsung-Hui Hu, Seng Gee Lim, Wan-Long Chuang
Publikováno v:
Clinical & Molecular Hepatology; Apr2024, Vol. 30 Issue 2, p191-205, 22p
Autor:
Sriram Narayanan, Veonice Bijin Au, Atefeh Khakpoor, Cheng Yan, Patricia J. Ahl, Nivashini Kaliaperumal, Bernett Lee, Wen Wei Xiang, Juling Wang, Chris Lee, Amy Tay, Seng Gee Lim, John E. Connolly
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Our objective was to examine differences in cytokine/chemokine response in chronic hepatitis B(CHB) patients to understand the immune mechanism of HBsAg loss (functional cure) during antiviral therapy. We used an unbiased machine learning st
Externí odkaz:
https://doaj.org/article/dd17137d36974df3b1796e6222c13612
Autor:
Daniel Q. Huang, Mark D. Muthiah, Lei Zhou, Halisah Jumat, Wan Xin Tan, Guan Huei Lee, Seng Gee Lim, Alfred Kow, Glenn Bonney, Iyer Shridhar, Yi Ting Lim, Aileen Wee, Yin Huei Pang, Gwyneth Soon, Pierce Chow, Yock Young Dan
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 5, Pp 1313-1325 (2021)
Background & Aims: Hepatocellular carcinoma (HCC) arises in a cirrhotic, pro-angiogenic microenvironment. Inhibiting angiogenesis is a key mode of action of multikinase inhibitors and current non-cirrhotic models are unable to predict treatment respo
Externí odkaz:
https://doaj.org/article/7ba8b6da13ae443ebf3680b9ffa1d1a7
Autor:
Daniel Q. Huang, Yee Hui Yeo, Eunice Tan, Hirokazu Takahashi, Satoshi Yasuda, Junji Saruwatari, Kenichi Tanaka, Kentaro Oniki, Leslie Y. Kam, Mark D. Muthiah, Hideyuki Hyogo, Masafumi Ono, Scott D. Barnett, Jie Li, Biyao Zou, James Fung, Teng‐Yu Lee, Vincent Wai‐Sun Wong, Man‐Fung Yuen, Yock Young Dan, Seng Gee Lim, Ramsey Cheung, Hidenori Toyoda, Yuichiro Eguchi, Mindie H. Nguyen
Publikováno v:
Hepatology Communications, Vol 4, Iss 11, Pp 1624-1636 (2020)
The current alanine aminotransferase (ALT) upper limit of normal was defined using selected healthy Caucasian blood donors. Given the global rise in obesity and different body habitus in Asians, we aimed to perform a systematic review and meta‐anal
Externí odkaz:
https://doaj.org/article/2b29eff3b15e435b988031a69b340246
Publikováno v:
Clinical and Molecular Hepatology, Vol 26, Iss 2, Pp 142-154 (2020)
Drug induced liver injury (DILI) may be different in the East compared to the West due to differing disease prevalence, prescribing patterns and pharmacogenetic profiles. To review existing literature on causative agents of DILI in the East compared
Externí odkaz:
https://doaj.org/article/3be2bac8a221485299e4a5454df9dc15
Autor:
Li Ren Kong, Nur Afiqah Binte Mohamed Salleh, Richard Weijie Ong, Tuan Zea Tan, Nicholas L. Syn, Robby Miguel Goh, Chee Wai Fhu, Daniel S. W. Tan, N. Gopalakrishna Iyer, Srinivasaraghavan Kannan, Chandra S. Verma, Yaw Chyn Lim, Ross Soo, Jingshan Ho, Yiqing Huang, Joline S. J. Lim, Benedict Junrong Yan, Min En Nga, Seng Gee Lim, H. Phillip Koeffler, Soo Chin Lee, Dennis Kappei, Huynh The Hung, Boon Cher Goh
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The MET receptor is frequently activated in cancer. Here, the authors show that in head and neck and lung squamous carcinoma, a polymorphic MET variant enhances binding to HER2, resulting in activation of HER2 signalling and progression of the cancer
Externí odkaz:
https://doaj.org/article/29d0a642abdc45549ef07f126485d155
Publikováno v:
Journal of Hepatology. 78:731-741
Hepatitis B core-related antigen(HBcrAg) is a new biomarker for Chronic Hepatitis B(CHB) but its performance has not been critically or systematically appraised.We evaluated the biological pathway of HBcrAg, and performed a systematic review of PubMe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e4bb49494093d1158e78e9979030acb
https://doi.org/10.1016/j.jhep.2022.12.017
https://doi.org/10.1016/j.jhep.2022.12.017