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IPO11 regulates the nuclear import of BZW1/2 and is necessary for AML cells and stem cells.

Autor: Nachmias B; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Hematology, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel., Khan DH; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Voisin V; Terrence Donnelly Centre for Cellular and Biomedical Research, University of Toronto, Toronto, ON, Canada., Mer AS; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Dept. of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada., Thomas GE; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Segev N; Department of Hematology, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel., St-Germain J; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Hurren R; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Gronda M; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Botham A; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada., Wang X; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Maclean N; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Seneviratne AK; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Duong N; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Xu C; Terrence Donnelly Centre for Cellular and Biomedical Research, University of Toronto, Toronto, ON, Canada., Arruda A; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Orouji E; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Algouneh A; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Hakem R; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada., Shlush L; Department of Immunology, The Weizmann Institute of Science, Rehovot, Israel., Minden MD; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada., Raught B; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada., Bader GD; Terrence Donnelly Centre for Cellular and Biomedical Research, University of Toronto, Toronto, ON, Canada., Schimmer AD; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada. aaron.schimmer@uhn.ca.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada. aaron.schimmer@uhn.ca.

Publikováno v: Leukemia [Leukemia] 2022 May; Vol. 36 (5), pp. 1283-1295. Date of Electronic Publication: 2022 Feb 12.

Transduction of Primary AML Cells with Lentiviral Vector for In Vitro Study or In Vivo Engraftment.

Autor: Schimmer AD; Princess Margaret Cancer Centre, University Health Network, Room 8-706, 101 College St., Toronto, ON M5G1L7, USA., Singh RP; Princess Margaret Cancer Centre, University Health Network, Room 8-706, 101 College St., Toronto, ON M5G1L7, USA., Seneviratne AK; Princess Margaret Cancer Centre, University Health Network, Room 8-706, 101 College St., Toronto, ON M5G1L7, USA., Thomas GE; Princess Margaret Cancer Centre, University Health Network, Room 8-706, 101 College St., Toronto, ON M5G1L7, USA., MacLean N; Princess Margaret Cancer Centre, University Health Network, Room 8-706, 101 College St., Toronto, ON M5G1L7, USA., Hurren R; Princess Margaret Cancer Centre, University Health Network, Room 8-706, 101 College St., Toronto, ON M5G1L7, USA.

Publikováno v: STAR protocols [STAR Protoc] 2020 Nov 25; Vol. 1 (3), pp. 100163. Date of Electronic Publication: 2020 Nov 25 (Print Publication: 2020).

Tafazzin modulates cellular phospholipid composition to regulate AML stemness.

Autor: Seneviratne AK; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Institute of Medical Sciences, Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Xu M; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Schimmer AD; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Institute of Medical Sciences, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.

Publikováno v: Molecular & cellular oncology [Mol Cell Oncol] 2019 Jun 11; Vol. 6 (5), pp. e1620051. Date of Electronic Publication: 2019 Jun 11 (Print Publication: 2019).