Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Senevirathne Se"'
Autor:
Will Swanson, Senevirathne Se, Myra G. Nunez, Tanya S. Freedman, Brian L. Ruis, Ben F Brian, Binstadt Ba, Branden S. Moriarity, Sauer Ml, Auger Jl, Clifford A. Lowell
The unique roles of the Src-family kinases LynA and LynB in immune activating and inhibitory signaling have eluded definition. Here we report that LynB, the shorter splice product of lyn, carries the dominant immunosuppressive function. We used CRISP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf903a9d59a6a1bfce9fae9d3c437179
https://doi.org/10.1101/2021.05.03.439514
https://doi.org/10.1101/2021.05.03.439514
Autor:
Brian BF 4th; Graduate Program in Molecular Pharmacology and Therapeutics, University of Minnesota, Minneapolis, MN 55455, USA., Sauer ML; Graduate Program in Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA., Greene JT; Department of Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA., Senevirathne SE; Graduate Program in Molecular Pharmacology and Therapeutics, University of Minnesota, Minneapolis, MN 55455, USA., Lindstedt AJ; Graduate Program in Microbiology, Immunology, and Cancer Biology, University of Minnesota, Minneapolis, MN 55455, USA.; Medical Scientist Training Program, University of Minnesota, Minneapolis, MN 55455, USA., Funk OL; Department of Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA., Ruis BL; Center for Genome Engineering, University of Minnesota, Minneapolis, MN 55455, USA., Ramirez LA; Department of Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA., Auger JL; Department of Pediatrics, Division of Rheumatology, Allergy and Immunology, University of Minnesota, Minneapolis, MN 55455, USA., Swanson WL; Department of Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA., Nunez MG; Department of Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA., Moriarity BS; Center for Genome Engineering, University of Minnesota, Minneapolis, MN 55455, USA.; Division of Pediatric Hematology and Oncology, Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.; Stem Cell Institute, University of Minnesota, Minneapolis, MN 55455, USA., Lowell CA; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Binstadt BA; Department of Pediatrics, Division of Rheumatology, Allergy and Immunology, University of Minnesota, Minneapolis, MN 55455, USA.; Center for Immunology, University of Minnesota, Minneapolis, MN 55455, USA., Freedman TS; Department of Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.; Center for Immunology, University of Minnesota, Minneapolis, MN 55455, USA.; Center for Autoimmune Diseases Research, University of Minnesota, Minneapolis, MN 55455, USA.
Publikováno v:
Science advances [Sci Adv] 2022 Apr 22; Vol. 8 (16), pp. eabj5227. Date of Electronic Publication: 2022 Apr 22.
Autor:
Greene JT; Department of Pharmacology, Center for Immunology, Masonic Cancer Center, and Center for Autoimmune Diseases Research, University of Minnesota, Minneapolis, MN, 55455, United States., Brian BF 4th; Department of Pharmacology, Center for Immunology, Masonic Cancer Center, and Center for Autoimmune Diseases Research, University of Minnesota, Minneapolis, MN, 55455, United States., Senevirathne SE; Department of Pharmacology, Center for Immunology, Masonic Cancer Center, and Center for Autoimmune Diseases Research, University of Minnesota, Minneapolis, MN, 55455, United States., Freedman TS; Department of Pharmacology, Center for Immunology, Masonic Cancer Center, and Center for Autoimmune Diseases Research, University of Minnesota, Minneapolis, MN, 55455, United States. Electronic address: tfreedma@umn.edu.
Publikováno v:
Current opinion in immunology [Curr Opin Immunol] 2021 Dec; Vol. 73, pp. 34-42. Date of Electronic Publication: 2021 Oct 01.