Trypsin in pancreatitis: The culprit, a mediator, or epiphenomenon?

Autor: Gukovskaya AS; Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA 90073, United States.; Department of Medicine, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, United States. agukovsk@ucla.edu., Lerch MM; Department of Medicine, Ludwig Maximilian University Hospital, Munich 81377, Germany., Mayerle J; Department of Medicine II, Ludwig Maximilian University of Munich, Munich 81377, Germany., Sendler M; Department of Medicine A, University of Greifswald, Greifswald 17475, Germany., Ji B; Department of Cancer Biology, Mayo Clinic, Jacksonville, FL 32224, United States., Saluja AK; Department of Surgery, University of Miami Miller School of Medicine, Miami, FL 33136, United States., Gorelick FS; Departments of Cell Biology and Internal Medicine, Yale University School of Medicine and VA West Haven, New Haven, CT 06519, United States., Gukovsky I; Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA 90073, United States.; Department of Medicine, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, United States.

Publikováno v: World journal of gastroenterology [World J Gastroenterol] 2024 Nov 07; Vol. 30 (41), pp. 4417-4438.

Fecal glycoprotein 2 is a marker of gut microbiota dysbiosis and systemic inflammation.

Autor: Frost F; Department of Medicine A, University Medicine Greifswald, Ferdinand-Sauerbruch- Straße, 17475, Greifswald, Germany., Weiss S; Department of Medicine A, University Medicine Greifswald, Ferdinand-Sauerbruch- Straße, 17475, Greifswald, Germany.; Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Hertel J; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany., Rühlemann M; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany., Bang C; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany., Franke A; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany., Nauck M; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany., Dörr M; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany., Völzke H; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Roggenbuck D; Institute of Biotechnology, Faculty Environment and Natural Sciences, Brandenburg University of Technology Cottbus-Senftenberg, Senftenberg, Germany.; Faculty of Health Sciences Brandenburg, Brandenburg University of Technology Cottbus-Senftenberg, Senftenberg, Germany., Schierack P; Institute of Biotechnology, Faculty Environment and Natural Sciences, Brandenburg University of Technology Cottbus-Senftenberg, Senftenberg, Germany.; Faculty of Health Sciences Brandenburg, Brandenburg University of Technology Cottbus-Senftenberg, Senftenberg, Germany., Völker U; Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Homuth G; Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Aghdassi AA; Department of Medicine A, University Medicine Greifswald, Ferdinand-Sauerbruch- Straße, 17475, Greifswald, Germany., Sendler M; Department of Medicine A, University Medicine Greifswald, Ferdinand-Sauerbruch- Straße, 17475, Greifswald, Germany., Lerch MM; Department of Medicine A, University Medicine Greifswald, Ferdinand-Sauerbruch- Straße, 17475, Greifswald, Germany., Weiss FU; Department of Medicine A, University Medicine Greifswald, Ferdinand-Sauerbruch- Straße, 17475, Greifswald, Germany. ulrich.weiss@med.uni-greifswald.de.

Publikováno v: Gut pathogens [Gut Pathog] 2024 Oct 19; Vol. 16 (1), pp. 60. Date of Electronic Publication: 2024 Oct 19.

The composition of the stent microbiome is associated with morbidity and adverse events during endoscopic drainage therapy of pancreatic necroses and pseudocysts.

Autor: Frost F; Department of Medicine A, University Medicine Greifswald, Greifswald, Germany., Khaimov V; Institute for Implant Technology and Biomaterials E. V., Rostock, Germany., Senz V; Institute for Biomedical Engineering, Rostock University Medical Center, Rostock, Germany., Weiss S; Department of Medicine A, University Medicine Greifswald, Greifswald, Germany.; Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Klußmann-Fricke B; Institute for Implant Technology and Biomaterials E. V., Rostock, Germany., Rühlemann M; Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany., Bang C; Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany., Franke A; Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany., Pickartz T; Department of Internal Medicine IV, Klinikum Südstadt Rostock, Rostock, Germany., Budde C; Department of Medicine A, University Medicine Greifswald, Greifswald, Germany., Aghdassi AA; Department of Medicine A, University Medicine Greifswald, Greifswald, Germany., Siewert S; Institute for Implant Technology and Biomaterials E. V., Rostock, Germany., Weiss FU; Department of Medicine A, University Medicine Greifswald, Greifswald, Germany., Grabow N; Institute for Biomedical Engineering, Rostock University Medical Center, Rostock, Germany., Lerch MM; Department of Medicine A, University Medicine Greifswald, Greifswald, Germany.; Ludwig Maximilian University Hospital, Ludwig Maximilian University of Munich, Munich, Germany., Sendler M; Department of Medicine A, University Medicine Greifswald, Greifswald, Germany.

Publikováno v: Frontiers in medicine [Front Med (Lausanne)] 2024 Sep 16; Vol. 11, pp. 1462122. Date of Electronic Publication: 2024 Sep 16 (Print Publication: 2024).

Induction of M2-macrophages by tumour cells and tumour growth promotion by M2-macrophages: A quid pro quo in pancreatic cancer

Autor: Partecke, L.I., Günther, C., Hagemann, S., Jacobi, C., Merkel, M., Sendler, M., van Rooijen, N., Käding, A., Nguyen Trung, D., Lorenz, E., Diedrich, S., Weiss, F.U., Heidecke, C.D., von Bernstorff, W.

Publikováno v: In Pancreatology September-October 2013 13(5):508-516

IRAK3-mediated suppression of pro-inflammatory MyD88/IRAK signaling affects disease severity in acute pancreatitis.

Autor: Thiel FG; Department of Medicine A, University Medicine, University of Greifswald, Fleischmannstr. 41, 17475, Greifswald, Germany., Asgarbeik S; Department of Medicine A, University Medicine, University of Greifswald, Fleischmannstr. 41, 17475, Greifswald, Germany., Glaubitz J; Department of Medicine A, University Medicine, University of Greifswald, Fleischmannstr. 41, 17475, Greifswald, Germany., Wilden A; Department of Medicine A, University Medicine, University of Greifswald, Fleischmannstr. 41, 17475, Greifswald, Germany., Lerch MM; Department of Medicine A, University Medicine, University of Greifswald, Fleischmannstr. 41, 17475, Greifswald, Germany., Weiss FU; Department of Medicine A, University Medicine, University of Greifswald, Fleischmannstr. 41, 17475, Greifswald, Germany., Sendler M; Department of Medicine A, University Medicine, University of Greifswald, Fleischmannstr. 41, 17475, Greifswald, Germany. matthias.sendler@uni-greifswald.de.

Publikováno v: Scientific reports [Sci Rep] 2023 Jul 04; Vol. 13 (1), pp. 10833. Date of Electronic Publication: 2023 Jul 04.