Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Senarath Dissanayake"'
Autor:
Allen Shahin, Senarath Dissanayake
Publikováno v:
Molecular Immunology. 44:1623-1630
Helminth parasites are known to alter host immune responses and the responsible molecules are a potential source of biological immunoadjuvants. Previously, we have reported strong Th-2 type immunomodulatory properties of Taenia crassiceps glycans. In
Publikováno v:
Molecular Immunology. 42:1495-1502
Complex glycans derived from lipid, nucleic acid and protein free extracts of Taenia crassiceps metacestode larvae were found to have adjuvant effect against Leishmania mexicana antigens in BALB/c mice experimentally infected with L. mexicana. A sing
Autor:
Senarath Dissanayake
Publikováno v:
Transactions of the Royal Society of Tropical Medicine and Hygiene. 98:156-164
The incidence of clinical tuberculosis and clinical leprosy among household members of tuberculosis and leprosy patients in Sri Lanka was studied. The study period was approximately 20 years (January 1981 to December 2001) and the total number of pat
Autor:
Senarath Dissanayake
Publikováno v:
Molecular Immunology. 38:911-919
Fucosylated sugars in Schistosoma mansoni possess immunomodulatory properties. In order to gain insights to the mechanisms involved, attempts were made to identify host immune cell molecules that specifically recognize these sugars. On Western blots,
Publikováno v:
Transactions of the Royal Society of Tropical Medicine and Hygiene. 95:591-594
A retrospective epidemiological analysis was performed of Mycobacterium tuberculosis infections in the Al Ain Medical District, Al Ain, United Arab Emirates (U.A.E.) during the period 1995-2000. The mean incidence for the study period was 7.1%, more
Autor:
Senarath Dissanayake, Joaquim Norões, Gerusa Dreyer, Willy F. Piessens, Abraham Rocha, Zulma Medeiros
Publikováno v:
Transactions of the Royal Society of Tropical Medicine and Hygiene. 94:526-530
The value of the polymerase chain reaction (PCR) in the diagnosis of Wuchereria bancrofti infection was evaluated in comparison to microscopical examination of night blood smears, Nuclepore filtration, serology and ultrasonography. No correlation was
Autor:
Senarath Dissanayake
Publikováno v:
International Journal for Parasitology. 30:1089-1097
Previously we have shown that in the filarial parasite Brugia malayi, stimulation with murine epidermal growth factor (EGF) upregulated the expression of the nuclear GTPase, Ran. In this paper we provide further evidence that filarial parasites posse
Autor:
Senarath Dissanayake, Huijun Zheng, Bijia Deng, Albert Vincent, Gerusa Dreyer, Min Xu, Guanghua Cheng, Laxman Watawana, Paul Morin, Shihai Wang, Liliana Kurniawan, Willy F. Piessens
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 50:727-734
We evaluated the usefulness of a recombinant parasite antigen (recSXP1) for the serologic diagnosis of lymphatic filariasis. A large proportion of sera from microfilaremic donors living in five different endemic countries (356 of 446 [80%]) contained
Publikováno v:
Molecular and Biochemical Parasitology. 56:259-267
We have isolated and characterized a gene encoding a novel GTP-binding protein of the GTPase superfamily in the filarial parasites Brugia malayi and Onchocerca volvulus. The deduced amino acid sequence of the cloned molecule has ∼ 30% overall homol
Publikováno v:
Molecular and Biochemical Parasitology. 56:269-277
By differentially screening an adult Brugia malayi cDNA library with sera from microfilaremic and amicrofilaremic donors infected with Wuchereria bancrofti, we have identified a novel parasite antigen denoted SXP-1. Recombinant SXP-1 filarial antigen