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Autor:
Gordon Turner, Jennifer Vogel, Sharon X. Wang, Thomas M. Smith, Brian DeChristopher, Jianning Yin, Liansheng Su, Amy Chen, Richard Zessis, Sena Fowler, Aaron C. Wilson, Alina Berdichevsky, Chun-Hao Chiu, Deborah M. Rothman, Frédéric Zecri, Heming Xing, Xinming Cai
Publikováno v:
Diabetes. 69(5)
Type 2 diabetes (T2D) is caused by loss of pancreatic β-cell mass and failure of the remaining β-cells to deliver sufficient insulin to meet demand. β-Cell glucolipotoxicity (GLT), which refers to combined, deleterious effects of elevated glucose