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pro vyhledávání: '"Sen-Bin Zhu"'
Autor:
Sen-Bin Zhu, Qian-Hu Jiang, Zhi-Guo Chen, Xiang Zhou, Yan-Ting Jin, Zixin Deng, Feng-Biao Guo
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 6, p e1011218 (2023)
Synthetic lethality (SL) occurs when mutations in two genes together lead to cell or organism death, while a single mutation in either gene does not have a significant impact. This concept can also be extended to three or more genes for SL. Computati
Externí odkaz:
https://doaj.org/article/f4f4e10bbab743709cd317b61e8f1cde
Autor:
Jiafeng, Yu, Wenwen, Jiang, Sen-Bin, Zhu, Zhen, Liao, Xianghua, Dou, Jian, Liu, Feng-Biao, Guo, Chuan, Dong
Publikováno v:
Methods. 210:10-19
Proteins encoded by small open reading frames (sORFs) can serve as functional elements playing important roles in vivo. Such sORFs also constitute the potential pool for facilitating the de novo gene birth, driving evolutionary innovation and species
Publikováno v:
ACS synthetic biology. 11(7)
Synthetic biology is an important interdisciplinary field that has emerged in this century, focusing on the rewriting and reprogramming of DNA through the cycles of "design-edit", and so, the cell's own operating system, its genome, is naturally comi