Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Semjon, Willier"'
Autor:
Tobias Feuchtinger, Peter Bader, Marion Subklewe, Maike Breidenbach, Semjon Willier, Markus Metzler, Nicola Gökbuget, Julia Hauer, Fabian Müller, Paul-Gerhardt Schlegel, Michael Frühwald, Christoph Schmid, Anja Troeger, Claudia Baldus, Roland Meisel, Annette Künkele, Max Topp, Jean-Pierre Bourquin, Gunnar Cario, Arend von Stackelberg, Christina Peters
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
The ongoing development of immunotherapies, including chimeric antigen receptor (CAR) T cells, has revolutionized cancer treatment. In paediatric relapsed/refractory B-lineage acute leukaemia antiCD19-CARs induced impressive initial response rates, w
Externí odkaz:
https://doaj.org/article/cc15f38b071a42af82ad7fe1cd60fd9d
Autor:
Franziska Blaeschke, Dana Stenger, Antonia Apfelbeck, Bruno L. Cadilha, Mohamed-Reda Benmebarek, Jasmin Mahdawi, Eva Ortner, Mareike Lepenies, Nicola Habjan, Felicitas Rataj, Semjon Willier, Theresa Kaeuferle, Robbie G. Majzner, Dirk H. Busch, Sebastian Kobold, Tobias Feuchtinger
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 6, Pp 1-6 (2021)
Externí odkaz:
https://doaj.org/article/af275a1b5c7a4ccfad9a71a7c9aa4002
Autor:
Franziska Blaeschke, Eva Ortner, Dana Stenger, Jasmin Mahdawi, Antonia Apfelbeck, Nicola Habjan, Tanja Weißer, Theresa Kaeuferle, Semjon Willier, Sebastian Kobold, Tobias Feuchtinger
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Therapeutic targeting of inhibitory checkpoint molecules in combination with chimeric antigen receptor (CAR) T cells is currently investigated in a variety of clinical studies for treatment of hematologic and solid malignancies. However, the impact o
Externí odkaz:
https://doaj.org/article/854adee3aa3543c4b4bbd7ad61959e1a
Autor:
Theresa Kaeuferle, Tanja A Stief, Stefan Canzar, Nayad N Kutlu, Semjon Willier, Dana Stenger, Paulina Ferrada‐Ernst, Nicola Habjan, Annika E Peters, Dirk H Busch, Tobias Feuchtinger
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 1, Pp n/a-n/a (2022)
Abstract Objectives Exploiting the forces of human T cells for treatment has led to the current paradigm of emerging immunotherapy strategies. Genetic engineering of the T‐cell receptor (TCR) redirects specificity, ablates alloreactivity and brings
Externí odkaz:
https://doaj.org/article/ab8c3e6d149d403c8001e8a0cca41eae
Autor:
Steffen Fuchs, Loélia Babin, Elissa Andraos, Chloé Bessiere, Semjon Willier, Johannes H Schulte, Christine Gaspin, Fabienne Meggetto
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0273253 (2022)
Circular RNA (circRNA) is a noncoding RNA class with important implications for gene expression regulation, mostly by interaction with other RNA species or RNA-binding proteins. While the commonly applied short-read Illumina RNA-sequencing techniques
Externí odkaz:
https://doaj.org/article/c43aca92b6ba4a2e9e96f0ac8785d8cb
Autor:
Semjon Willier, Karin Melanie Cabanillas Stanchi, Martina von Have, Vera Binder, Franziska Blaeschke, Judith Feucht, Tobias Feuchtinger, Michaela Döring
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background Chemotherapy-induced nausea and vomiting (CINV) belong among the most burdensome side effects in hemato-oncology. Mostly, a combination of ondansetron and dexamethasone is used as antiemetic prophylaxis in pediatric patients under
Externí odkaz:
https://doaj.org/article/40dde7f3da78498c81cb29aeb9c1fa59
Publikováno v:
Journal of Hematology & Oncology, Vol 12, Iss 1, Pp 1-10 (2019)
Abstract Background Allogeneic hematopoietic stem cell transplantation (HSCT) can expose patients to a transient but marked immunosuppression, during which viral infections are an important cause of morbidity and mortality. Adoptive transfer of virus
Externí odkaz:
https://doaj.org/article/0a306c3437d34157adfd1c0bcaaafd8b
Autor:
Armin Wolf, Semjon Willier, Johannes Raedler, Franziska Blaeschke, Dana Stenger, Montserrat Pazos Escudero, Florian Jurgeleit, Thomas G P Grünewald, Vera Binder, Irene Schmid, Michael H Albert, Tobias Feuchtinger
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Relapsed/refractory B-precursor acute lymphoblastic leukemia (BCP-ALL) remains a major therapeutic challenge in pediatric hematology. Chimeric antigen receptor (CAR) T cells targeting CD19 have shown remarkable initial response rates in BC
Externí odkaz:
https://doaj.org/article/27c8b25d5ad94f20ab2fed383e907a26
Autor:
Tanja A. Stief, Tobias Feuchtinger, Dirk H. Busch, Judith Feucht, Lena M. Jablonowski, Michaela Döring, Franziska Blaeschke, Kilian Schober, Semjon Willier, T. Müller, Rupert Handgretinger, Theresa Kaeuferle, Peter Lang, Kevin M. Dennehy
Publikováno v:
Mol Ther
Viral infections cause life-threatening disease in immunocompromised patients and especially following transplantation. T cell receptor (TCR) engineering redirects specificity and can bring significant progress to emerging adoptive T cell transfer (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f00110f797b5ee6d2d76053b53d8a16f
https://doi.org/10.1016/j.ymthe.2021.05.021
https://doi.org/10.1016/j.ymthe.2021.05.021
CLEC12A and CD33 coexpression as a preferential target for pediatric AML combinatorial immunotherapy
Autor:
Christoph Klein, Theresa Kaeuferle, Maximilian Hastreiter, Jonas Wilhelm, Meino Rohlfs, Marion Subklewe, Tobias Feuchtinger, Dana Stenger, Paula Rothämel, Franziska Blaeschke, Michael H. Albert, Vera Binder, Irene Schmid, Semjon Willier
Publikováno v:
Blood. 137:1037-1049
Emerging immunotherapies such as chimeric antigen receptor T cells have advanced the treatment of acute lymphoblastic leukemia. In contrast, long-term control of acute myeloid leukemia (AML) cannot be achieved by single lineage-specific targeting whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b2eba26e50d110185763262e0549a47
https://doi.org/10.1182/blood.2020006921
https://doi.org/10.1182/blood.2020006921