Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Semi Lim"'
Autor:
Dae Gyu Kim, Yongseok Choi, Yuno Lee, Semi Lim, Jiwon Kong, JaeHa Song, Younah Roh, Dipesh S. Harmalkar, Kwanshik Lee, Ja-il Goo, Hye Young Cho, Ameeq Ul Mushtaq, Jihye Lee, Song Hwa Park, Doyeun Kim, Byung Soh Min, Kang Young Lee, Young Ho Jeon, Sunkyung Lee, Kyeong Lee, Sunghoon Kim
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Direct targeting of oncogenic KRAS activity is a challenge. Here the authors report that a splice variant of AIMP2, AIMP2-DX2, enhances KRAS stability by blocking ubiquitin-mediated degradation of KRAS via the E3 ligase, Smurf2, and identify a chemic
Externí odkaz:
https://doaj.org/article/f7b60731b1ef420298a16914d07b8a55
Autor:
Ashutosh Bahuguna, Vishal Kumar, Gajanan Bodkhe, Srinivasan Ramalingam, SeMi Lim, Ah-ryeong Joe, Jong Suk Lee, So-Young Kim, Myunghee Kim
Publikováno v:
Foods, Vol 12, Iss 22, p 4084 (2023)
The typical Korean diet contains a significant quantity of doenjang owing to its unique taste and health benefits. However, the presence of anti-nutritional and toxic substances, such as biogenic amines and microbial pathogens, in doenjang has result
Externí odkaz:
https://doaj.org/article/5ca61c1748c243b7b974e5cfc25f3993
Autor:
Srinivasan Ramalingam, Ashutosh Bahuguna, SeMi Lim, Ah-Ryeong Joe, Jong-Suk Lee, So-Young Kim, Myunghee Kim
Publikováno v:
Foods, Vol 11, Iss 3, p 375 (2022)
Gochujang, fermented red pepper paste, is a grain-based Korean traditional food. The quality of gochujang produced by cottage industries is not well-documented. Thus, the present study aimed to analyze the quality of gochujang from 35 traditional cot
Externí odkaz:
https://doaj.org/article/60a883d17dac49c8992a02dcc20c3ea8
Autor:
Srinivasan Ramalingam, Ashutosh Bahuguna, SeMi Lim, Ah-ryeong Joe, Jong-Suk Lee, So-Young Kim, Myunghee Kim
Publikováno v:
Foods, Vol 10, Iss 10, p 2370 (2021)
Traditional gochujang is well known for its distinguished flavor and taste. However, the safety of cottage industry gochujang products is uncertain, particularly, in terms of biogenic amine (BA) content which is not yet documented. The present study
Externí odkaz:
https://doaj.org/article/0bd2ba69a32840aaa2fdf8ea167b3bc7
Publikováno v:
Molecules, Vol 25, Iss 12, p 2763 (2020)
While aminoacyl-tRNA synthetase-interacting multifunctional protein 2 (AIMP2) is a tumor suppressor, its exon 2-depleted splice variant (AIMP2-DX2 or shortly DX2) is highly expressed in human lung cancer, and the ratio of DX2 to AIMP2 increases accor
Externí odkaz:
https://doaj.org/article/0c7881a8254548de942a17e123be1779
Autor:
Dae Gyu Kim, Thi Thu Ha Nguyen, Nam Hoon Kwon, Junsik Sung, Semi Lim, Eun-Joo Kang, Jihye Lee, Woo Young Seo, Arum Kim, Yoon Soo Chang, Hyunbo Shim, Sunghoon Kim
Publikováno v:
Biomolecules, Vol 10, Iss 6, p 820 (2020)
AIMP2-DX2, an exon 2-deleted splice variant of AIMP2 (aminoacyl-tRNA synthetase-interacting multifunctional protein 2), is highly expressed in lung cancer and involved in tumor progression in vivo. Oncogenic function of AIMP2-DX2 and its correlation
Externí odkaz:
https://doaj.org/article/f3bea71a026e4f46840e14efab5ddd6b
Autor:
Ji-Hyun Lee, Kyoung Mii Park, Dong-Jin Han, Nam Young Bang, Do-Hee Kim, Hyeongjin Na, Semi Lim, Tae Bum Kim, Dae Gyu Kim, Hyun-Jung Kim, Yeonseok Chung, Sang Hyun Sung, Young-Joon Surh, Sunghoon Kim, Byung Woo Han
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142624 (2015)
Despite the growing attention given to Traditional Medicine (TM) worldwide, there is no well-known, publicly available, integrated bio-pharmacological Traditional Korean Medicine (TKM) database for researchers in drug discovery. In this study, we hav
Externí odkaz:
https://doaj.org/article/68239d1c63fa4bebb1266688438f318f
Autor:
Kyungmi Lee, Semi Lim
Publikováno v:
Journal of Korean Gerontological Nursing. 24:433-440
Purpose: This study aimed to identify the health empowerment, social support, and health-promotion behavior of older adults. Furthermore, the factors influencing health-promotion behavior were identified. Methods: A cross-sectional descriptive study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c78c9555841bdb0d20511a8fd77fb77
https://doi.org/10.17079/jkgn.2022.24.4.433
https://doi.org/10.17079/jkgn.2022.24.4.433
Autor:
Zigang Dong, Ki Won Lee, Ann M. Bode, Hyong Joo Lee, Mee-Hyun Lee, Ji Young Kim, Kanamata Reddy, Semi Lim, Lee Farrand, Chul-Ho Jeong, Jihoon Lee, Sung-Young Lee, Sanguine Byun
Supplementary Figures and Legends - PDF file 2854K, Supplementary Figure 1. Effect of USP8 knockdown on cell viability Supplementary Figure 2. Effect of USP8 knockdown on EGFR wildtype cells and apoptosis of NSCLC and normal cells. Supplementary Figu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e7fdeda2a3af750cd83e459245e985
https://doi.org/10.1158/1078-0432.22446666.v1
https://doi.org/10.1158/1078-0432.22446666.v1
Autor:
Zigang Dong, Ki Won Lee, Ann M. Bode, Hyong Joo Lee, Mee-Hyun Lee, Ji Young Kim, Kanamata Reddy, Semi Lim, Lee Farrand, Chul-Ho Jeong, Jihoon Lee, Sung-Young Lee, Sanguine Byun
Purpose: Common treatment modalities for non–small cell lung cancer (NSCLC) involve the EGF receptor-tyrosine kinase inhibitors (EGFR-TKIs) like gefitinib and erlotinib. However, the vast majority of treated patients acquire resistance to EGFR-TKIs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ab5b1cf4a0a64f346025f31013716d
https://doi.org/10.1158/1078-0432.c.6520821.v1
https://doi.org/10.1158/1078-0432.c.6520821.v1