Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Semer Maksoud"'
Autor:
Markus W. Schweiger, Zohreh Amoozgar, Pierre Repiton, Robert Morris, Semer Maksoud, Michael Hla, Eric Zaniewski, David P. Noske, Wilhelm Haas, Koen Breyne, Bakhos A. Tannous
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108807- (2024)
Summary: Glioblastoma (GBM) is the most aggressive brain tumor, presenting major challenges due to limited treatment options. Standard care includes radiation therapy (RT) to curb tumor growth and alleviate symptoms, but its impact on GBM is limited.
Externí odkaz:
https://doaj.org/article/db23f5ee32a4459ab10e27118100af65
Autor:
Semer Maksoud, Joelle El Hokayem
Publikováno v:
Heliyon, Vol 9, Iss 4, Pp e15055- (2023)
HIV infection progressively weakens the immune system by infecting and destroying cells involved in host defense. Viral infection symptoms are generated and aggravated as immunosuppression progresses, triggered by the presence of opportunistic infect
Externí odkaz:
https://doaj.org/article/360272680fb4494892c71117de8dfc9a
Autor:
Semer Maksoud, Adriana Mayora, Laura Colma, Felipe Sojo, Adriana Pimentel, Vladimir Kouznetsov, Diego Merchán-Arena, Ángel Romero, Francisco Arvelo, Juan Bautista De Sanctis, Gustavo Benaim
Publikováno v:
Investigación Clínica. 63:243-261
Tetrahydroquinoline derivatives are interesting structures exhib-iting a wide range of biological activities, including antitumor effects. In this investigation, the effect of the synthesized tetrahydroquinolines JS-56 and JS-92on apoptosis, intracel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea452c5d53c75c751ffde7534eb48569
https://doi.org/10.54817/ic.v63n3a04
https://doi.org/10.54817/ic.v63n3a04
Autor:
Semer Maksoud
Publikováno v:
Molecular Neurobiology. 59:5326-5365
Gliomas are the most frequent type of tumor in the central nervous system, which exhibit properties that make their treatment difficult, such as cellular infiltration, heterogeneity, and the presence of stem-like cells responsible for tumor recurrenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2371f6c76776abccbd512520fd51063b
https://doi.org/10.1007/s12035-022-02915-2
https://doi.org/10.1007/s12035-022-02915-2
Autor:
Semer Maksoud
Publikováno v:
Molecular Neurobiology. 58:3252-3269
Gliomas constitute the most frequent tumors of the brain. High-grade gliomas are characterized by a poor prognosis caused by a set of attributes making treatment difficult, such as heterogeneity and cell infiltration. Additionally, there is a subgrou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee94e90cfd5b3d78ae977658e22e334
https://doi.org/10.1007/s12035-021-02339-4
https://doi.org/10.1007/s12035-021-02339-4
Autor:
Bakhos A. Tannous, John W. Chen, Ichiro Nakano, Elie Tabet, Ralph Mazitschek, Aleksandar B. Kirov, Romain J. Amante, Antoinette E. Nibbs, Norman H. L. Chiu, Myriam Boukhali, Christian E. Badr, Evelyn Fitzsimons, Semer Maksoud, Cintia Carla da Hora, Wilhelm Haas
Publikováno v:
ACS Chem Biol
We have previously identified the natural product obtusaquinone (OBT) as a potent antineoplastic agent with promising in vivo activity in glioblastoma and breast cancer through the activation of oxidative stress; however, the molecular properties of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62376458087d8e0550e0cbadc65ba53c
https://doi.org/10.1021/acschembio.0c00104
https://doi.org/10.1021/acschembio.0c00104
We describe a generalizable time-resolved Förster resonance energy transfer (TR-FRET)-based platform to profile the cellular action of heterobifunctional degraders (or proteolysis-targeting chimeras; PROTACs), capable of both accurately quantifying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0664022aeb860281c7b771e1f30fe645
https://doi.org/10.1101/2021.12.08.471806
https://doi.org/10.1101/2021.12.08.471806
