Zobrazeno 1 - 10
of 496
pro vyhledávání: '"Sema4D"'
Autor:
Błażej Ochman, Piotr Limanówka, Sylwia Mielcarska, Agnieszka Kula, Miriam Dawidowicz, Wiktor Wagner, Dorota Hudy, Monika Szrot, Jerzy Zbigniew Piecuch, Jerzy Piecuch, Zenon Czuba, Elżbieta Świętochowska
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 9, Pp 10218-10248 (2024)
Semaphorins (SEMAs), ADAM, and ADAMTS family members are implicated in various cancer progression events within the tumor microenvironment across different cancers. In this study, we aimed to evaluate the expression of SEMA7A, SEMA4D, ADAM8, and ADAM
Externí odkaz:
https://doaj.org/article/797d7f81f61a459abb0609505bc3479b
Autor:
Yao Liao, Zifeng Zhu, Yuheng Liu, Ji Wu, Dinghao Li, Zhen Li, Junhao Xu, Ruibing Yang, Lifu Wang
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-13 (2023)
Abstract Background Macrophages and neutrophils are rapidly recruited around Schistosome eggs to form granulomas. Extracellular traps (ETs) of macrophages and neutrophils are part of the pathogen clearance armamentarium of leukocytes. Schistosome egg
Externí odkaz:
https://doaj.org/article/676b16274d354fb9bcec8ded295a4764
Autor:
Yuanyuan Cui, Xiaomei Jiang, Maozhu Yang, Yinglin Yuan, Zili Zhou, Xiang Gao, Guiqing Jia, Lvzhou Cao, Danni Li, Yanshuang Zhao, Xin Zhang, Gaoping Zhao
Publikováno v:
Materials Today Bio, Vol 23, Iss , Pp 100832- (2023)
Cardiovascular disease remains the leading cause of death and morbidity worldwide. Inflammatory responses after percutaneous coronary intervention led to neoathrosclerosis and in-stent restenosis and thus increase the risk of adverse clinical outcome
Externí odkaz:
https://doaj.org/article/02908d57bebd4b6994078716f5ab9dd0
Autor:
Zhenen Lin, Shengren Xiong, Yu Lin, Zhaohui Li, Dan Xie, Xuchao Lin, Xuesheng Chen, Xueyi Lin
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 18, Iss 1, Pp 1-13 (2023)
Abstract Purpose The current study aims to investigate the regulatory impact of leptin or melatonin on bone metabolism as well as the underlying mechanism in conjunction with Sema4D (monoclonal antibody to semaphorin 4D). Methods Rats were used to cr
Externí odkaz:
https://doaj.org/article/6e5ad2f2ddfa4fb1ad77d7966eaebe41
Publikováno v:
European Journal of Medical Research, Vol 28, Iss 1, Pp 1-7 (2023)
Abstract Background Bisphosphonates (BPs) are widely used in clinical practice to prevent and treat bone metabolism-related diseases. Medication-related osteonecrosis of the jaw (MRONJ) is one of the major sequelae of BPs use. Early prediction and in
Externí odkaz:
https://doaj.org/article/11c7e31ee32c4321aac9f388e24ddff3
Akademický článek
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Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
PurposeThis study aims to examine the effects of leptin and melatonin intervention on bone metabolism in ovariectomize (OVX) rodents, as well as their potential mechanisms of action.MethodsPrepare an OVX model of osteoporosis in rodents and validate
Externí odkaz:
https://doaj.org/article/945e577380904e429491eef48fb7ad85
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Semaphorin 4D (SEMA4D) is considered a new antitumor target closely related to immune cells. However, understanding the role of SEMA4D in the tumor microenvironment (TME) is limited. In this study, we explored the expression and immune cell infiltrat
Externí odkaz:
https://doaj.org/article/e12a4f96a85a40c8b713db05c1cc53e3
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Background Acute myeloid leukemia (AML) is the most common type of acute leukemia in adults. SEMA4D is a 150 kDa transmembrane protein that belongs to the IV class of the subfamily of semaphorin family. Previous studies have reported that SE
Externí odkaz:
https://doaj.org/article/3c149c680ebb42b39d01eeae07652fef
Autor:
Zhuo Zhang, Duoli Zhang, Fang Wang, Jiao Liu, Yuhong Sun, Songyot Anuchapreeda, Singkome Tima, Zhangang Xiao, Suwit Duangmano
Publikováno v:
PeerJ, Vol 11, p e15172 (2023)
Melanoma is a common skin tumor that causes a high rate of mortality, especially in Europe, North America and Oceania. Immunosuppressants such as anti-PD-1 have been used in the treatment of malignant melanoma, however, nearly 60% of patients do not
Externí odkaz:
https://doaj.org/article/4d721755a94046f9b8db78cd72c6dc01