Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sema Oncel"'
Autor:
Sema Oncel, Qinggang Wang, Ahmed Adham R Elsayed, Emilie E Vomhof-DeKrey, Nicholas D Brown, Mikhail Y Golovko, Svetlana A Golovko, Ricardo Gallardo-Macias, Vadim J Gurvich, Marc D Basson
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0304010 (2024)
M64HCl, which has drug-like properties, is a water-soluble Focal Adhesion Kinase (FAK) activator that promotes murine mucosal healing after ischemic or NSAID-induced injury. Since M64HCl has a short plasma half-life in vivo (less than two hours), it
Externí odkaz:
https://doaj.org/article/eaf4a03f8e64424fb7b4fef3415f9b94
Autor:
Qinggang Wang, Ricardo Gallardo-Macias, Emilie E. Vomhof-DeKrey, Rashmi Gupta, Svetlana A. Golovko, Mikhail Y. Golovko, Sema Oncel, Vadim J. Gurvich, Marc D. Basson
Publikováno v:
Current Research in Pharmacology and Drug Discovery, Vol 4, Iss , Pp 100147- (2023)
Non-steroidal anti-inflammatory drugs (NSAIDs) injure the proximal and distal gut by different mechanisms. While many drugs reduce gastrointestinal injury, no drug directly stimulates mucosal wound healing. Focal adhesion kinase (FAK), a non-receptor
Externí odkaz:
https://doaj.org/article/d0e700f3f0f94c29b62d9ab5274beecb
Publikováno v:
Cells, Vol 10, Iss 4, p 908 (2021)
Nonsteroidal anti-inflammatory drugs cause gastric ulcers and gastritis. No drug that treats GI injury directly stimulates mucosal healing. ZINC40099027 (ZN27) activates focal adhesion kinase (FAK) and heals acute indomethacin-induced small bowel inj
Externí odkaz:
https://doaj.org/article/fb3337c4f41546e4bac93f3ade6dd0e7
Autor:
Sema Oncel, Marc D. Basson
Publikováno v:
Cell and Tissue Research. 390:261-279
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::767ca446ebb57e89e76b64ad8ad5947f
https://doi.org/10.1007/s00441-022-03674-1
https://doi.org/10.1007/s00441-022-03674-1
Autor:
Ricardo Gallardo-Macias, Shyam K. More, Vadim J. Gurvich, Sema Oncel, Mikhail Y. Golovko, Marc D. Basson, Rashmi, Ahmed Adham Raafat Elsayed, Qinggang Wang
Publikováno v:
ACS Med Chem Lett
[Image: see text] Gastrointestinal mucosal wounds are common to patients injured by factors as diverse as drugs, inflammatory bowel disease, peptic ulcers, and necrotizing enterocolitis. However, although many drugs are used to ameliorate injurious f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f3a507a57e8606cc9884a2aabf696d
https://doi.org/10.1021/acsmedchemlett.0c00311
https://doi.org/10.1021/acsmedchemlett.0c00311
Autor:
Ricardo Gallardo-Macias, Rashmi Rashmi, Marc D. Basson, Qinggang Wang, Sema Oncel, Vadim J. Gurvich
Publikováno v:
Gastroenterology. 160:S-97
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eee2d141bdc6a8dff4fdc008db408ef8
https://doi.org/10.1016/s0016-5085(21)00976-8
https://doi.org/10.1016/s0016-5085(21)00976-8
Autor:
Marc D. Basson, Sema Oncel
Publikováno v:
Gastroenterology. 160:S-650
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abdf76e4af33942db2b0f3d74569ec6f
https://doi.org/10.1016/s0016-5085(21)02264-2
https://doi.org/10.1016/s0016-5085(21)02264-2
Autor:
Selmin Gülbahar, Canan Altay, Gözde Özcan Söylev, Özlem El, Çiğdem Bircan, Metin Manisalı, Özlen Peker, Meltem Baydar, Sema Öncel
Publikováno v:
Türk Osteoporoz Dergisi, Vol 14, Iss 1, Pp 1-6 (2008)
Aim: The aim of this study was to investigate the relationship between vertebral fractures and spondylosis and bone mineral density in men older than 60 years. Material and Method: Thirty-two men with back and low back pain aged over 60 years were i
Externí odkaz:
https://doaj.org/article/6f6a8e8a1df949d5b5d75f369bb95f62
Autor:
Özlem El, Çiğdem Bircan, Ebru Şahin, Burcu Adalmaz, Elif Keskin Pehlivan, Ramazan Kızıl, Özlem Şenocak, Özlen Peker, Sema Öncel
Publikováno v:
Türk Osteoporoz Dergisi, Vol 10, Iss 4, Pp 153-156 (2004)
Osteoporosis in men is increasingly recognized as an important public health issue because of mortality and disability. Approximately 25-30% of all hip fractures occur in men and men are over 3 times more likely to die following a hip fracture than w
Externí odkaz:
https://doaj.org/article/a4091f30e8254fe2ba73a3ff3cec096e