Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Selvi, Srinivasan"'
Autor:
Zach R. Demkovich, Manjula Gunawardana, Ronald S. Veazey, Ariane van der Straten, Paul L. Feldman, John A. Moss, Ivana Massud, Alessandro Grattoni, Duy Khiet Ho, Frank DIana, Doris Zane, Mark Milad, Fernanda P. Pons-Faudoa, Marc M. Baum, Shane Roller, Thomas J. Hope, Joseph Romano, Charles Dobard, Selvi Srinivasan, J. Gerardo García-Lerma
Publikováno v:
AIDS Research and Human Retroviruses
The ability to successfully develop a safe and effective vaccine for the prevention of HIV infection has proven challenging. Consequently, alternative approaches to HIV infection prevention have been pursued, and there have been a number of successes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1960ae602db1d3b15e8c97bb2bac13c
https://doi.org/10.1089/aid.2021.0028
https://doi.org/10.1089/aid.2021.0028
Autor:
Anthony J. Convertine, T. Eoin West, Debobrato Das, Patrick S. Stayton, Taylor Monroe-Jones, Jasmin Chen, Brian Lee, Daniel M. Ratner, Hye Nam Son, Frank Radella, Shawn J. Skerrett, Dale Whittington, Fang-Yi Su, Selvi Srinivasan
Publikováno v:
Biomaterials. 195:38-50
Alveolar macrophages resident in the lung are prominent phagocytic effector cells of the pulmonary innate immune response, and paradoxically, are attractive harbors for pathogens. Consequently, facultative intracellular bacteria, such as Francisella
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0cc1f9e718233989a44d3eb068bb0f
https://doi.org/10.1016/j.biomaterials.2018.10.017
https://doi.org/10.1016/j.biomaterials.2018.10.017
Autor:
Anthony J. Convertine, Jasmin Chen, Courtney Reichhardt, Fang-Yi Su, Shawn J. Skerrett, Daniel M. Ratner, Selvi Srinivasan, Daniel Passos da Silva, Debobrato Das, Elaine Limqueco, Patrick S. Stayton, Matthew R. Parsek
Publikováno v:
ACS Infect Dis
Biofilms are one of the most challenging obstacles in bacterial infections. By providing protection against immune responses and antibiotic therapies, biofilms enable chronic colonization and the development of antibiotic resistance. As previous clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b48d959944e88d937fda75756f7d360d
https://europepmc.org/articles/PMC7769119/
https://europepmc.org/articles/PMC7769119/
Autor:
Brian Lee, Thomas E.J. Chavas, Guilhem F. Rerolle, Fang-Yi Su, Debashish Roy, Elaine Limqueco, Selvi Srinivasan, T. Eoin West, Lara Lovelace-Macon, Patrick S. Stayton, Shawn J. Skerrett, Daniel M. Ratner
Publikováno v:
J Control Release
Pulmonary melioidosis is a bacterial disease with high morbidity and a mortality rate that can be as high as 40% in resource-poor regions of South Asia. This disease burden is linked to the pathogen's intrinsic antibiotic-resistance and protected int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee847b7e3198ca8e0422d52e40fbe20
https://pubmed.ncbi.nlm.nih.gov/33221351
https://pubmed.ncbi.nlm.nih.gov/33221351
Autor:
Hans E. Huber, Jing Zhang, Rosemary Rochford, Paul A. Burke, Duy-Khiet Ho, Brandon S. Pybus, Debashish Roy, Ayumi Pottenger, Siobhan M. Flaherty, Pamela Strauch, Vladimir A. Vlaskin, Patrick S. Stayton, Conner L. Jackson, Thomas E.J. Chavas, Mahdi Maktabi, Hsiuling Lin, Clare L.M. LeGuyader, Selvi Srinivasan, David Wesche, Qigui Li
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 331
Primaquine and tafenoquine are the two 8-aminoquinoline (8-AQ) antimalarial drugs approved for malarial radical cure - the elimination of liver stage hypnozoites after infection with Plasmodium vivax. A single oral dose of tafenoquine leads to high e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6678b8ca58b45191d6bfcca05c991316
https://pubmed.ncbi.nlm.nih.gov/33378692
https://pubmed.ncbi.nlm.nih.gov/33378692
Autor:
Clare L.M. LeGuyader, Selvi Srinivasan, Debashish Roy, Almar Postma, John Chiefari, Vladimir A. Vlaskin, Jessica M. Snyder, Patrick S. Stayton, Duy-Khiet Ho, Thomas E.J. Chavas, Ciana L. Lopez
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 329
Clinical studies have validated that antiretroviral (ARV) drugs can serve as an HIV pre-exposure prophylactic (PrEP) strategy. Dosing adherence remains a crucial factor determining the final efficacy outcomes, and both long-acting implants and inject
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20dcb6b42b127449eed9f746f90e0626
https://pubmed.ncbi.nlm.nih.gov/33217474
https://pubmed.ncbi.nlm.nih.gov/33217474
Autor:
Alexander, Dart, Debashish, Roy, Vladimir, Vlaskin, Elaine, Limqueco, Neona M, Lowe, Selvi, Srinivasan, Daniel M, Ratner, Mrinal, Bhave, Patrick, Stayton, Peter, Kingshott
Publikováno v:
Biomaterials Advances. 133:112626
HIV and hepatitis B are two of the most prevalent viruses globally, and despite readily available preventive treatments unforgiving treatment regimens still exist, such as daily doses of medicine that are challenging to maintain especially in poorer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddeb49d9468e72540c75c76fc58d5172
https://doi.org/10.1016/j.msec.2021.112626
https://doi.org/10.1016/j.msec.2021.112626
Autor:
Shawn J. Skerrett, Selvi Srinivasan, Patrick S. Stayton, Anthony J. Convertine, Daniel M. Ratner, Brian Lee, Fang-Yi Su, Jasmin Chen, T.E. West
Publikováno v:
Journal of Controlled Release. 287:1-11
Intracellular bacterial infections localized to the lung alveolar macrophage (AM) remain one of the most challenging settings for antimicrobial therapy. Current systemic antibiotic treatment fails to deliver sustained doses to intracellular bacterial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f14e9b37624733958bded040eda4906d
https://doi.org/10.1016/j.jconrel.2018.08.014
https://doi.org/10.1016/j.jconrel.2018.08.014
Autor:
Justin M. Kollman, Daniel M. Ratner, Patrick S. Stayton, F. D. Brown, Selvi Srinivasan, Almar Postma, Debobrato Das, Fang-Yi Su, Anthony J. Convertine, Anika L. Burrell
Publikováno v:
Polymer Chemistry. 9:2134-2146
Radiant star nanoparticle (RSN) prodrugs were synthesized in a two-step process by first homopolymerizing RAFT transmers followed by copolymerization from the hyperbranched polymer core. Two trithiocarbonate-based transmers were synthesized containin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8984febee519c3a1f3d9623832e94392
https://doi.org/10.1039/c8py00202a
https://doi.org/10.1039/c8py00202a
Publikováno v:
Polym Chem
Herein, we developed a fully polymerizable, peptide-targeted, camptothecin polymeric prodrug system. Two prodrug monomers were synthesized via esterification of campothecin (20Cam) and 10-hydroxycamptothecin (10Cam) with mono-2-(methacryloyloxy)ethyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b93e31e29253aada3abf71e2127074
https://doi.org/10.1039/c8py01047a
https://doi.org/10.1039/c8py01047a