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A ZEB1-miR-375-YAP1 pathway regulates epithelial plasticity in prostate cancer

Autor: Philip A. Gregory, Margaret M. Centenera, Lisa M. Butler, Brett G. Hollier, Rajdeep Das, Nataly Stylianou, Wayne D. Tilley, Scott L. Townley, Adrienne R. Hanson, Amina Zoubeidi, Gregory J. Goodall, Carolina Soekmadji, Katrina Sweeney, Colleen C. Nelson, Isabel Coutinho, Lidija Jovanovic, Luke A. Selth

Publikováno v: Europe PubMed Central

MicroRNA-375 (miR-375) is frequently elevated in prostate tumors and cell-free fractions of patient blood, but its role in genesis and progression of prostate cancer is poorly understood. In this study, we demonstrated that miR-375 is inversely corre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5549098e1f1e0f76eea7aa0600bb3b3b
https://pubmed.ncbi.nlm.nih.gov/27270433

Author Correction: CDK9 inhibition constrains multiple oncogenic transcriptional and epigenetic pathways in prostate cancer.

Autor: Rahman R; Flinders University, College of Medicine and Public Health, Flinders Health and Medical Research Institute, Bedford Park, SA, Australia., Rahaman MH; Drug Discovery and Development, Clinical and Health Sciences, University of South Australia, Adelaide, SA, Australia., Hanson AR; Flinders University, College of Medicine and Public Health, Flinders Health and Medical Research Institute, Bedford Park, SA, Australia., Choo N; Biomedicine Discovery Institute Cancer Program, Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia., Xie J; Flinders University, College of Medicine and Public Health, Flinders Health and Medical Research Institute, Bedford Park, SA, Australia., Townley SL; Flinders University, College of Medicine and Public Health, Flinders Health and Medical Research Institute, Bedford Park, SA, Australia., Shrestha R; Flinders University, College of Medicine and Public Health, Flinders Health and Medical Research Institute, Bedford Park, SA, Australia.; Flinders University, Freemasons Centre for Male Health and Wellbeing, Bedford Park, SA, Australia., Hassankhani R; Drug Discovery and Development, Clinical and Health Sciences, University of South Australia, Adelaide, SA, Australia., Islam S; Drug Discovery and Development, Clinical and Health Sciences, University of South Australia, Adelaide, SA, Australia., Ramm S; Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; The Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC, Australia., Simpson KJ; Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; The Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC, Australia.; Department of Biochemistry and Pharmacology, University of Melbourne, Parkville, VIC, Australia., Risbridger GP; Biomedicine Discovery Institute Cancer Program, Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia.; The Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC, Australia.; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; Cabrini Institute, Cabrini Health, Malvern, Melbourne, VIC, Australia.; Melbourne Urological Research Alliance (MURAL), Monash Biomedicine Discovery Institute Cancer Program, Monash University, Clayton, VIC, Australia., Best G; Flinders University, College of Medicine and Public Health, Flinders Health and Medical Research Institute, Bedford Park, SA, Australia., Centenera MM; South Australian Health and Medical Research Institute, Adelaide, SA, Australia.; Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, Australia., Balk SP; Beth Israel Deaconess Medical Center, Boston, MA, USA., Kichenadasse G; Flinders University, College of Medicine and Public Health, Flinders Health and Medical Research Institute, Bedford Park, SA, Australia.; Department of Medical Oncology, Flinders Medical Centre, Southern Adelaide Local Health Network, Adelaide, SA, South Australia., Taylor RA; The Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC, Australia.; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; Cabrini Institute, Cabrini Health, Malvern, Melbourne, VIC, Australia.; Melbourne Urological Research Alliance (MURAL), Monash Biomedicine Discovery Institute Cancer Program, Monash University, Clayton, VIC, Australia.; Biomedicine Discovery Institute Cancer Program, Department of Physiology, Monash University, Clayton, VIC, Australia., Butler LM; South Australian Health and Medical Research Institute, Adelaide, SA, Australia.; Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, Australia., Tilley WD; Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, Australia.; Dame Roma Mitchell Cancer Research Laboratories, Adelaide Medical School, The University of Adelaide, Adelaide, SA, Australia., Conn SJ; Flinders University, College of Medicine and Public Health, Flinders Health and Medical Research Institute, Bedford Park, SA, Australia., Lawrence MG; Biomedicine Discovery Institute Cancer Program, Prostate Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia.; The Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC, Australia.; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; Cabrini Institute, Cabrini Health, Malvern, Melbourne, VIC, Australia.; Melbourne Urological Research Alliance (MURAL), Monash Biomedicine Discovery Institute Cancer Program, Monash University, Clayton, VIC, Australia., Wang S; Drug Discovery and Development, Clinical and Health Sciences, University of South Australia, Adelaide, SA, Australia., Selth LA; Flinders University, College of Medicine and Public Health, Flinders Health and Medical Research Institute, Bedford Park, SA, Australia. luke.selth@flinders.edu.au.; Flinders University, Freemasons Centre for Male Health and Wellbeing, Bedford Park, SA, Australia. luke.selth@flinders.edu.au.; Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, Australia. luke.selth@flinders.edu.au.

Publikováno v: British journal of cancer [Br J Cancer] 2024 Nov; Vol. 131 (10), pp. 1719.