Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane.

Autor: González-López A; Department of Cell and Molecular Biology, Uppsala University, BMC, P.O. Box 596, 75124, Uppsala, Sweden., Larsson DSD; Department of Cell and Molecular Biology, Uppsala University, BMC, P.O. Box 596, 75124, Uppsala, Sweden., Koripella RK; Department of Cell and Molecular Biology, Uppsala University, BMC, P.O. Box 596, 75124, Uppsala, Sweden.; Robert P. Apkarian Integrated Electron Microscopy Core, Emory University, Atlanta, USA., Cain BN; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA., Chavez MG; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA., Hergenrother PJ; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA., Sanyal S; Department of Cell and Molecular Biology, Uppsala University, BMC, P.O. Box 596, 75124, Uppsala, Sweden., Selmer M; Department of Cell and Molecular Biology, Uppsala University, BMC, P.O. Box 596, 75124, Uppsala, Sweden. maria.selmer@icm.uu.se.

Publikováno v: Scientific reports [Sci Rep] 2024 Jun 20; Vol. 14 (1), pp. 14253. Date of Electronic Publication: 2024 Jun 20.

Phage T3 overcomes the BREX defense through SAM cleavage and inhibition of SAM synthesis by SAM lyase.

Autor: Andriianov A; Skolkovo Institute of Science and Technology, Moscow 143028, Russia., Trigüis S; Department of Cell and Molecular Biology, Uppsala University, BMC, Box 596, 751 24 Uppsala, Sweden., Drobiazko A; Skolkovo Institute of Science and Technology, Moscow 143028, Russia., Sierro N; Philip Morris International R&D, Philip Morris Products S.A., 2000 Neuchatel, Switzerland., Ivanov NV; Philip Morris International R&D, Philip Morris Products S.A., 2000 Neuchatel, Switzerland., Selmer M; Department of Cell and Molecular Biology, Uppsala University, BMC, Box 596, 751 24 Uppsala, Sweden. Electronic address: maria.selmer@icm.uu.se., Severinov K; Waksman Institute of Microbiology, Piscataway, NJ 08854, USA. Electronic address: severik@waksman.rutgers.edu., Isaev A; Skolkovo Institute of Science and Technology, Moscow 143028, Russia. Electronic address: artem.isaev@skoltech.ru.

Publikováno v: Cell reports [Cell Rep] 2023 Aug 29; Vol. 42 (8), pp. 112972. Date of Electronic Publication: 2023 Aug 13.

Structural mechanism of AadA, a dual-specificity aminoglycoside adenyltransferase from Salmonella enterica

Autor: Stern, A.L., Van der Verren, S.E., Kanchugal P, S., Näsvall, J., Gutiérrez-de-Terán, H., Selmer, M.

Publikováno v: 'Journal of Biological Chemistry ', vol: 293, pages: 11481-11490 (2018)

Streptomycin and spectinomycin are antibiotics that bind to the bacterial ribosome and perturb protein synthesis. The clinically most prevalent bacterial resistance mechanism is their chemical modification by aminoglycoside-modifying enzymes such as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=illesrfpubli::94c34548214a37adf8dbd674cfee5292
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ESRF:49911

A Tournament Problem

Autor: Ford,, Lester R., Johnson, Selmer M.

Publikováno v: The American Mathematical Monthly, 1959 May 01. 66(5), 387-389.

Externí odkaz: https://www.jstor.org/stable/2308750

Structure and mechanism of a phage-encoded SAM lyase revises catalytic function of enzyme family.

Autor: Guo X; Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden., Söderholm A; Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden., Kanchugal P S; Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden., Isaksen GV; Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden.; Hylleraas Centre for Quantum Molecular Sciences, Department of Chemistry, UiT - The Arctic University of Norway, Tromsø, Norway., Warsi O; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden., Eckhard U; Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden., Trigüis S; Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden., Gogoll A; Department of Chemistry-BMC, Uppsala University, Uppsala, Sweden., Jerlström-Hultqvist J; Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden.; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden., Åqvist J; Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden., Andersson DI; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden., Selmer M; Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden.

Publikováno v: ELife [Elife] 2021 Feb 10; Vol. 10. Date of Electronic Publication: 2021 Feb 10.