Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Selma P Wiertsema"'
Autor:
Elke J Seppanen, Ruth B Thornton, Karli J Corscadden, Caitlyn M Granland, Julie Hibbert, Angela Fuery, Selma P Wiertsema, Shyan Vijayasekaran, Harvey L Coates, Peter Jacoby, Andrew Currie, Peter C Richmond, Lea-Ann S Kirkham
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0227080 (2019)
Recurrent and chronic otitis media (OM) are often refractory to antibiotics due to bacterial persistence in biofilm within the middle ear. In vitro and in vivo studies have demonstrated that antimicrobial proteins and peptides (AMPs) are bactericidal
Externí odkaz:
https://doaj.org/article/7584fa9e659047ddacefbfa91adbf024
Autor:
Ruth B Thornton, Selma P Wiertsema, Lea-Ann S Kirkham, Paul J Rigby, Shyan Vijayasekaran, Harvey L Coates, Peter C Richmond
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e53837 (2013)
BACKGROUND: Bacteria persist within biofilms on the middle ear mucosa of children with recurrent and chronic otitis media however the mechanisms by which these develop remain to be elucidated. Biopsies can be difficult to obtain from children and the
Externí odkaz:
https://doaj.org/article/118fb187ad534f0fa727a94b88a757fb
Autor:
Selma P Wiertsema, Karli J Corscadden, Eva N Mowe, Guicheng Zhang, Shyan Vijayasekaran, Harvey L Coates, Timothy J Mitchell, Wayne R Thomas, Peter C Richmond, Lea-Ann S Kirkham
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49061 (2012)
BackgroundVaccines including conserved antigens from Streptococcus pneumoniae and nontypeable Haemophilus influenzae (NTHi) have the potential to reduce the burden of acute otitis media. Little is known about the antibody response to such antigens in
Externí odkaz:
https://doaj.org/article/49c3e2c5c7c64f2384f656f5c7a1bede
Autor:
Michael J Binks, Beth Temple, Lea-Ann Kirkham, Selma P Wiertsema, Eileen M Dunne, Peter C Richmond, Robyn L Marsh, Amanda J Leach, Heidi C Smith-Vaughan
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e34083 (2012)
BACKGROUND: Unambiguous identification of nontypeable Haemophilus influenzae (NTHi) is not possible by conventional microbiology. Molecular characterisation of phenotypically defined NTHi isolates suggests that up to 40% are Haemophilus haemolyticus
Externí odkaz:
https://doaj.org/article/6755d25223624dae969f7dd2c166b0e5
Autor:
Elke J. Seppanen, Harvey Coates, Karli J. Corscadden, Peter Richmond, Selma P. Wiertsema, Hannah J.D. North, Ruth B. Thornton, Peter Jacoby, Shyan Vijayasekaran, Lea Ann S. Kirkham
Publikováno v:
Pediatric Infectious Disease Journal. 39:91-96
BACKGROUND Repeat ventilation tube insertion (VTI) is common in children with recurrent acute otitis media (rAOM). Identifying risk factors associated with repeat surgery will improve clinical management and prevent repeat VTI. METHODS Surgical recor
Autor:
Tulia Mateus, Elke J. Seppanen, Camilla de Gier, Sharon Clark, Harvey Coates, Shyan Vijayasekaran, Karen Prosser, Selma P. Wiertsema, Angela Fuery, Lea-Ann S. Kirkham, Peter C. Richmond, Ruth B. Thornton
Publikováno v:
Frontiers in cellular and infection microbiology. 12
BackgroundThe underlying pathogenesis of pediatric obstructive sleep disordered breathing (SDB) and recurrent tonsillitis (RT) are poorly understood but need to be elucidated to develop less invasive treatment and prevention strategies.MethodsChildre
Autor:
Angela Fuery, Anthony D. Keil, Peter Richmond, B. Jan Jones, Lea-Ann S. Kirkham, Shyan Vijayasekaran, Guicheng Zhang, Selma P. Wiertsema, Ruth B. Thornton, Karli J. Corscadden, Harvey Coates
Publikováno v:
Clinical and Vaccine Immunology : CVI
Indigenous populations experience high rates of otitis media (OM), with increased chronicity and severity, compared to those experienced by their nonindigenous counterparts. Data on immune responses to otopathogenic bacteria in these high-risk popula
Autor:
Sarra E. Jamieson, Marie S. Rye, Ruth B. Thornton, Selma P. Wiertsema, Elizabeth S. H. Scaman, Jenefer M. Blackwell, Harvey Coates, Richard W. Francis, Shyan Vijayasekaran
Publikováno v:
Infection, Genetics and Evolution. 16:411-418
Otitis media (OM) is a common disease in early childhood characterised by inflammation of the middle ear. Susceptibility to recurrent acute OM (rAOM; ⩾3 episodes AOM in 6 months) and chronic OM with effusion (COME; middle ear effusion ⩾3 months)
Autor:
Ruth B. Thornton, Selma P. Wiertsema, Tulia Mateus, Karli J. Corscadden, Peter Richmond, Lea-Ann S. Kirkham, Gemma L. Mullaney, Guicheng Zhang
Publikováno v:
Clinical and Vaccine Immunology : CVI
The pneumococcus is a major otitis media (OM) pathogen, but data are conflicting regarding whether otitis-prone children have impaired humoral immunity to pneumococcal antigens. We and others have shown that otitis-prone and healthy children have sim
Autor:
Angela Fuery, Lea-Ann S. Kirkham, Gary C. Geelhoed, Christopher C Blyth, F. Mascaro, Andrew J. Currie, Selma P. Wiertsema, Nicholas Conway, Peter Richmond
Publikováno v:
Vaccine. 29:5107-5113
Introduction Increased numbers of children presenting with febrile adverse events following trivalent influenza vaccine (TIV) were noted in Australia in 2010. We describe the epidemiology and clinical features of the adverse events and explore the bi