Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Selma Mahmutovic"'
Autor:
Lars E. Clark, Selma Mahmutovic, Donald D. Raymond, Taleen Dilanyan, Takaaki Koma, John T. Manning, Sundaresh Shankar, Silvana C. Levis, Ana M. Briggiler, Delia A. Enria, Kai W. Wucherpfennig, Slobodan Paessler, Jonathan Abraham
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
The five known New World hemorrhagic fever arenaviruses use the same entry receptor, but their viral glycoproteins are markedly different. Here, the authors isolate monoclonal antibodies from a Junin virus vaccinated person that cross-neutralize Mach
Externí odkaz:
https://doaj.org/article/daef1e9d51b8461ba2ffa8c665295132
Molecular Basis for Antibody-Mediated Neutralization of New World Hemorrhagic Fever Mammarenaviruses
Autor:
Selma Mahmutovic, Lars Clark, Jonathan Abraham, Ana M. Briggiler, Silvana Levis, Stephen C. Harrison, Delia Enria
Publikováno v:
Cell Host & Microbe. 18(6):705-713
In the Western hemisphere, at least five mammarenaviruses cause human viral hemorrhagic fevers with high case fatality rates. Junín virus (JUNV) is the only hemorrhagic fever virus for which transfusion of survivor immune plasma that contains neutra
Autor:
Kai W. Wucherpfennig, Ana M. Briggiler, Delia Enria, Lars Clark, Sundaresh Shankar, Silvana Levis, Takaaki Koma, Donald D. Raymond, Slobodan Paessler, Selma Mahmutovic, John T. Manning, Jonathan Abraham, Taleen Dilanyan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Nature Communications
Nature Communications
While five arenaviruses cause human hemorrhagic fevers in the Western Hemisphere, only Junin virus (JUNV) has a vaccine. The GP1 subunit of their envelope glycoprotein binds transferrin receptor 1 (TfR1) using a surface that substantially varies in s