Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Selma Maacha"'
Autor:
Mohammed Soutto, Xing Zhang, Nadeem Bhat, Zheng Chen, Shoumin Zhu, Selma Maacha, Melanie Genoula, Omar El-Gazzaz, Dunfa Peng, Heng Lu, Oliver G. McDonald, Xi Steven Chen, Longlong Cao, Zekuan Xu, Wael El-Rifai
Publikováno v:
Redox Biology, Vol 69, Iss , Pp 102998- (2024)
Helicobacter pylori (H. pylori) is the leading risk factor for gastric carcinogenesis. Fibroblast growth factor receptor 4 (FGFR4) is a member of transmembrane tyrosine kinase receptors that are activated in cancer. We investigated the role of FGFR4
Externí odkaz:
https://doaj.org/article/d1ea9f85b0eb45219072afc3c9463aca
Autor:
Ajaz A. Bhat, Sabah Nisar, Soumi Mukherjee, Nirmalya Saha, Nageswari Yarravarapu, Saife N. Lone, Tariq Masoodi, Ravi Chauhan, Selma Maacha, Puneet Bagga, Punita Dhawan, Ammira Al-Shabeeb Akil, Wael El-Rifai, Shahab Uddin, Ravinder Reddy, Mayank Singh, Muzafar A. Macha, Mohammad Haris
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Gene editing has great potential in treating diseases caused by well-characterized molecular alterations. The introduction of clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9)–based gene-
Externí odkaz:
https://doaj.org/article/5c11bfa5c37549b0b549f3c86a885fe3
Autor:
Ajaz A. Bhat, Sabah Nisar, Mayank Singh, Bazella Ashraf, Tariq Masoodi, Chandra P. Prasad, Atul Sharma, Selma Maacha, Thasni Karedath, Sheema Hashem, Syed Besina Yasin, Puneet Bagga, Ravinder Reddy, Michael P. Frennaux, Shahab Uddin, Punita Dhawan, Mohammad Haris, Muzafar A. Macha
Publikováno v:
Cancer Communications, Vol 42, Iss 8, Pp 689-715 (2022)
Abstract Colorectal cancer (CRC) is a predominant life‐threatening cancer, with liver and peritoneal metastases as the primary causes of death. Intestinal inflammation, a known CRC risk factor, nurtures a local inflammatory environment enriched wit
Externí odkaz:
https://doaj.org/article/1b69ad614aa84c8bb0d9900ad6dc3fe6
Autor:
Jun Hong, Selma Maacha, Nataliya Pidkovka, Andreia Bates, Safia N. Salaria, Mary K. Washington, Abbes Belkhiri
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
AXL receptor tyrosine kinase promotes an invasive phenotype and chemotherapy resistance in esophageal adenocarcinoma (EAC). AXL has been implicated in the regulation of autophagy, but the underlying molecular mechanism remains poorly understood. Here
Externí odkaz:
https://doaj.org/article/dc71a2124e354061ae083647876bf739
Autor:
Ajaz A. Bhat, Sabah Nisar, Selma Maacha, Tatiana Correa Carneiro-Lobo, Sabah Akhtar, Kodappully Sivaraman Siveen, Nissar A. Wani, Arshi Rizwan, Puneet Bagga, Mayank Singh, Ravinder Reddy, Shahab Uddin, Jean-Charles Grivel, Gyan Chand, Michael P. Frenneaux, Mushtaq A. Siddiqi, Davide Bedognetti, Wael El-Rifai, Muzafar A. Macha, Mohammad Haris
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-20 (2021)
Abstract Esophageal cancer (EC) is a disease often marked by aggressive growth and poor prognosis. Lack of targeted therapies, resistance to chemoradiation therapy, and distant metastases among patients with advanced disease account for the high mort
Externí odkaz:
https://doaj.org/article/93508395f39f499988e58d9ffbdea3d9
Autor:
Houda Yasmine Ali Moussa, Nimshitha Manaph, Gowher Ali, Selma Maacha, Kyung Chul Shin, Samia M. Ltaief, Vijay Gupta, Yongfeng Tong, Janarthanan Ponraj, Salam Salloum-Asfar, Said Mansour, Fouad A. Al-Shaban, Hyung-Goo Kim, Lawrence W. Stanton, Jean-Charles Grivel, Sara A. Abdulla, Abeer R. Al-Shammari, Yongsoo Park
Publikováno v:
Frontiers in Integrative Neuroscience, Vol 16 (2022)
Extracellular vesicles (EVs) are membrane vesicles released from cells to the extracellular space, involved in cell-to-cell communication by the horizontal transfer of biomolecules such as proteins and RNA. Because EVs can cross the blood-brain barri
Externí odkaz:
https://doaj.org/article/f7807d86e65542a59f1dad50f74540a1
Autor:
Sanaa Sharari, Mustapha Aouida, Idris Mohammed, Basma Haris, Ajaz Ahmad Bhat, Iman Hawari, Sabah Nisar, Igor Pavlovski, Kabir H. Biswas, Najeeb Syed, Selma Maacha, Jean-Charles Grivel, Maryam Saifaldeen, Johan Ericsson, Khalid Hussain
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Fanconi–Bickel Syndrome (FBS) is a rare disorder of carbohydrate metabolism that is characterized mainly by the accumulation of glycogen in the liver and kidney. It is inherited as an autosomal recessive disorder caused by mutations in the SLC2A2 g
Externí odkaz:
https://doaj.org/article/2d01c00c404341fe90e54f1b061e3e51
Autor:
Selma Maacha, Ajaz A. Bhat, Lizandra Jimenez, Afsheen Raza, Mohammad Haris, Shahab Uddin, Jean-Charles Grivel
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-16 (2019)
Abstract The tumor microenvironment represents a complex network, in which tumor cells not only communicate with each other but also with stromal and immune cells. Current research has demonstrated the vital role of the tumor microenvironment in supp
Externí odkaz:
https://doaj.org/article/dcc6e6d06ddd43788653862eecd0dc4f
Autor:
Sanaa Sharari, Basirudeen Kabeer, Idris Mohammed, Basma Haris, Igor Pavlovski, Iman Hawari, Ajaz Ahmad Bhat, Mohammed Toufiq, Sara Tomei, Rebecca Mathew, Najeeb Syed, Sabah Nisar, Selma Maacha, Jean-Charles Grivel, Damien Chaussabel, Johan Ericsson, Khalid Hussain
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2114 (2022)
Fanconi–Bickel Syndrome (FBS) is a rare disorder of carbohydrate metabolism that is characterized by the accumulation of glycogen mainly in the liver. It is inherited in an autosomal recessive manner due to mutations in the SLC2A2 gene. SLC2A2 enco
Externí odkaz:
https://doaj.org/article/fdc507a460194407a6173afa34a196b8
Publikováno v:
Molecular Oncology, Vol 12, Iss 12, Pp 2191-2208 (2018)
AXL receptor tyrosine kinase is overexpressed in esophageal adenocarcinoma (EAC) and several other types of malignancies; hence, it may be a valuable therapeutic target. Herein, we investigated the role of AXL in regulating c‐MYC expression and res
Externí odkaz:
https://doaj.org/article/0f5b74139a50496ba15e2ebcd8fe1267