Výsledky vyhledávání - "Selina Kofler"

Towards fast, routine blood sample quality evaluation by Probe Electrospray Ionization (PESI) metabolomics

Autor: Erxleben B, Martina Tomberger, Hidekazu S, Barbara Prietl, Bordag N, Erdem Y, Elmar Zügner, Al-Baghdadi A, Selina Kofler, Schweiger J, Christoph Magnes, Wadsak W, Pablo López-García

PESI-MS enables with its greatly simplified handling and fast result delivery the application field for high-throughput use in routine settings. In health care and research, pre-analytical errors often remain undetected and disrupt diagnosis, treatme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3330eb99994536eace37c94b88d70dcc
https://doi.org/10.1101/2021.04.18.21254782

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Author response for 'Hypoglycaemia leads to a delayed increase in platelet and coagulation activation markers in people with type 2 diabetes treated with metformin only: Results from a stepwise hypoglycaemic clamp study'

Autor: null Felix Aberer, null Peter N. Pferschy, null Norbert J. Tripolt, null Caren Sourij, null Anna Maria Obermayer, null Florian Prüller, null Eva Novak, null Philipp Reitbauer, null Harald Kojzar, null Barbara Prietl, null Selina Kofler, null Martina Brunner, null Eva Svehlikova, null Tatjana Stojakovic, null Hubert Scharnagl, null Abderrahim Oulhaj, null Faisal Aziz, null Regina Riedl, null Harald Sourij

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a8691e8f485f8ee9462615020586d07
https://doi.org/10.1111/dom.13889/v3/response1

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SAT0272 RITUXIMAB SIGNIFICANTLY DIMINISHES CD86+ B CELLS IN SYSTEMIC SCLEROSIS

Autor: Florentine C. Fürst-Moazedi, Barbara Dreo, Selina Kofler, Hans-Peter Brezinsek, Winfried Graninger, Angelika Lackner, Monica D'Orazio, Harald Sourij, Barbara Prietl, Martin H Stradner

Publikováno v: Saturday, 15 June 2019.

Background: Rituximab (RTX) is a monoclonal antibody that targets the CD20 surface marker. This results in a reduction of CD20+ immune cell populations, foremost B cells. B cell depletion via RTX was found to be beneficial for patients suffering from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::371016e076c6613957723fc0e878d1c7
https://doi.org/10.1136/annrheumdis-2019-eular.8047

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116-OR: Hypoglycemia Leads to a Delayed Increase in Platelet and Coagulation Markers in Subjects with Type 2 Diabetes Treated with Metformin Only—Results from an Experimental Stepwise Hypoglycemic Clamp Study

Autor: Norbert J. Tripolt, Abderrahim Oulhaj, Philipp Reitbauer, Martina Brunner, Regina Riedl, Barbara Prietl, Harald Kojzar, Selina Kofler, Felix Aberer, Eva Novak, Faisal Aziz, Tatjana Stojakovic, Florian Prüller, Anna Obermayer, Peter N. Pferschy, Harald Sourij, Hubert Scharnagl, Caren Sourij

Publikováno v: Diabetes. 68

Objective: Although hypoglycemia is associated with increased risk for subsequent cardiovascular events, experimental data investigating the effect of hypoglycemia on coagulation and platelet activation in type 2 diabetes are limited. Research Design

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::33a83f69a914d39383049eadef557206
https://doi.org/10.2337/db19-116-or

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Hypoglycaemia leads to a delayed increase in platelet and coagulation activation markers in people with type 2 diabetes treated with metformin only: Results from a stepwise hypoglycaemic clamp study

Autor: Hubert Scharnagl, Florian Prüller, Harald Kojzar, Philipp Reitbauer, Martina Brunner, Eva Novak, Peter N. Pferschy, Caren Sourij, Abderrahim Oulhaj, Tatjana Stojakovic, Norbert J. Tripolt, Anna Obermayer, Selina Kofler, Eva Svehlikova, Harald Sourij, Faisal Aziz, Barbara Prietl, Felix Aberer, Regina Riedl

Publikováno v: Diabetes, Obesity & Metabolism

AIMS To investigate the effect of hypoglycaemia on platelet and coagulation activation in people with type 2 diabetes. MATERIALS AND METHODS This monocentric, open, single-arm, mechanistic trial included 14 people with established type 2 diabetes (fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9183186adbbe6dd34a46975d49e3e4e1
https://pubmed.ncbi.nlm.nih.gov/31595635

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THU0031 ABATACEPT ALTERS THE FREQUENCY OF IMMUNOREGULATORY AND EFFECTOR T CELL SUBPOPULATIONS IN RHEUMATOID ARTHRITIS

Autor: Selina Kofler, Barbara Dreo, Martin H Stradner, Barbara Prietl, Florentine Moazedi-Fürst, Monica D'Orazio, Angelika Lackner, Harald Sourij, Winfried Graninger, Hans Peter Brezinschek

Publikováno v: Annals of the Rheumatic Diseases. 79:229.2-229

Background:Under physiological conditions, T regulatory cells (Tregs) are responsible for the downregulation of the immune response. In autoimmune diseases, such as rheumatoid arthritis (RA), auto-inflammation is driven by an imbalance of activation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::da725f7a1ca0a70bc1887ddeb57db857
https://doi.org/10.1136/annrheumdis-2020-eular.4894

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AB0146 DRUG DEPENDENT ALTERATIONS IN B-CELL REPERTOIRE IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS WITH LOW DISEASE ACTIVITY

Autor: Barbara Dreo, Judith Gretler, Selina Kofler, Florentine C. Fürst-Moazedi, Martin H Stradner, Winfried Graninger, Monica D'Orazio, Sabine Zenz, Harald Sourij, Barbara Prietl, Hans-Peter Brezinsek, Angelika Lackner, Kerstin Brickmann

Publikováno v: Annals of the Rheumatic Diseases. 79:1373.2-1373

Background:B-cells play a major role in the pathogenesis and perpetuation of the immune response in systemic lupus erythematosus (SLE). So far, B-cell subtypes have been studied well, but the precise mechanisms of the B-cell alterations during diseas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::df23e06c87dba07cd26cf2d33f6316c1
https://doi.org/10.1136/annrheumdis-2020-eular.4412

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Low-Dose IL-2 Signaling Is Specifically Impaired in Regulatory T Cells from T1D Patients

Autor: Thomas R. Pieber, Barbara Prietl, Selina Kofler, Barbara Obermayer-Pietsch, Harald Sourij, Stefanie Stanzer

Publikováno v: Diabetes. 67

Background: The response to interleukin-2 (IL-2) is essential for the stability and function of regulatory T cells (Tregs) in vivo. Impaired IL-2 receptor signaling might play a crucial role in the decreased function of Tregs in autoimmunity but migh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f983e1bf832fa49b5265c6f72e6a5003
https://doi.org/10.2337/db18-101-or

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