Zobrazeno 1 - 10
of 216
pro vyhledávání: '"Selina Chen-Kiang"'
Autor:
Zachary A. Hing, Janek S. Walker, Ethan C. Whipp, Lindsey Brinton, Matthew Cannon, Pu Zhang, Steven Sher, Casey B. Cempre, Fiona Brown, Porsha L. Smith, Claudio Agostinelli, Stefano A. Pileri, Jordan N. Skinner, Katie Williams, Hannah Phillips, Jami Shaffer, Larry P. Beaver, Alexander Pan, Kyle Shin, Charles T. Gregory, Gulcin H. Ozer, Selen A. Yilmaz, Bonnie K. Harrington, Amy M. Lehman, Lianbo Yu, Vincenzo Coppola, Pearlly Yan, Peggy Scherle, Min Wang, Philip Pitis, Chaoyi Xu, Kris Vaddi, Selina Chen-Kiang, Jennifer Woyach, James S. Blachly, Lapo Alinari, Yiping Yang, John C. Byrd, Robert A. Baiocchi, Bradley W. Blaser, Rosa Lapalombella
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Richter’s Transformation is a treatment-resistant and fatal progression from Chronic Lymphocytic Leukemia (CLL) to an aggressive lymphoma. Here, the authors show that PRMT5 is upregulated months prior to and after transformation, PRMT5 overexpressi
Externí odkaz:
https://doaj.org/article/69b4b26dffde485788921c4c7e1fc14a
Autor:
Walter Hanel, Pushpa Lata, Youssef Youssef, Ha Tran, Liudmyla Tsyba, Lalit Sehgal, Bradley W. Blaser, Dennis Huszar, JoBeth Helmig-Mason, Liwen Zhang, Morgan S. Schrock, Matthew K. Summers, Wing Keung Chan, Alexander Prouty, Bethany L. Mundy-Bosse, Selina Chen-Kiang, Alexey V. Danilov, Kami Maddocks, Robert A. Baiocchi, Lapo Alinari
Publikováno v:
Experimental Hematology & Oncology, Vol 11, Iss 1, Pp 1-19 (2022)
Abstract Background Mantle cell lymphoma (MCL) is a rare, highly heterogeneous type of B-cell non-Hodgkin’s lymphoma. The sumoylation pathway is known to be upregulated in many cancers including lymphoid malignancies. However, little is known about
Externí odkaz:
https://doaj.org/article/cf2c01ff3b1143099fc83be472ac2f3f
Autor:
Ja-Young Jang, Inah Hwang, Heng Pan, Jun Yao, Lapo Alinari, Eddie Imada, Claudio Zanettini, Michael J. Kluk, Yizhe Wang, Yunkyoung Lee, Hua V. Lin, Xiangao Huang, Maurizio Di Liberto, Zhengming Chen, Karla V. Ballman, Lewis C. Cantley, Luigi Marchionni, Giorgio Inghirami, Olivier Elemento, Robert A. Baiocchi, Selina Chen-Kiang, Sandro Belvedere, Hongwu Zheng, Jihye Paik
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 24 (2022)
Targeting lineage-defined transcriptional dependencies has emerged as an effective therapeutic strategy in cancer treatment. Through screening for molecular vulnerabilities of mantle cell lymphoma (MCL), we identified a set of transcription factors (
Externí odkaz:
https://doaj.org/article/e15c9cf4b48849f098c33b46bf6b5433
Autor:
Selina Chen-Kiang, John P. Leonard, Christopher E. Mason, Olivier Elemento, Scott Ely, Betty Chang, Amy Johnson, Siraj Ali, Ken Eng, Priyanka Vijay, Susan Mathew, Pedro Blecua, Jeff Sharman, Xiangao Huang, Peter Martin, Maurizio Di Liberto, David Chiron
Significant non-synonymous damaging SNVs detected in CDS by targeted exome sequencing in Pt 2 relapse sample.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::050ea228bec608ef0334889577ff68c1
https://doi.org/10.1158/2159-8290.22532134.v1
https://doi.org/10.1158/2159-8290.22532134.v1
Autor:
Selina Chen-Kiang, John P. Leonard, Christopher E. Mason, Olivier Elemento, Scott Ely, Betty Chang, Amy Johnson, Siraj Ali, Ken Eng, Priyanka Vijay, Susan Mathew, Pedro Blecua, Jeff Sharman, Xiangao Huang, Peter Martin, Maurizio Di Liberto, David Chiron
Figure S1. MCL cell lines are differentially sensitive to killing and cell cycle control by ibrutinib.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3238466bb9477978c0a21c4b9b98fa3e
https://doi.org/10.1158/2159-8290.22532152.v1
https://doi.org/10.1158/2159-8290.22532152.v1
Autor:
Maureen E. Lane, Morton Coleman, Selina Chen-Kiang, Donna Skerret, Scott Ely, Zhaoying Xiang, Karen Pekle, Faiza Zafar, Tsiporah B. Shore, Lena Mathews, Paul J. Christos, Jessica Stern, Megan Manco, Roger N. Pearse, David S. Jayabalan, Maureen Ward, Tomer M. Mark, Ruben Niesvizky
PDF file - 58K, Study design and patient flow by intent to treat (ITT).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45ea303679dbde4a3397e161607c8dd5
https://doi.org/10.1158/1078-0432.22451307.v1
https://doi.org/10.1158/1078-0432.22451307.v1
Autor:
Steven M. Lipkin, Leandro Cerchietti, Haiyuan Yu, Robert J. Klein, Kenneth Offit, Nicola J. Camp, Charles G. Mullighan, Henry T. Lynch, Charles Dumontet, Robert G. Roeder, Mark J. Daly, Kenneth C. Anderson, Judy E. Garber, Jane Churpek, Lucy A. Godley, Susan L. Slager, Ola Landgren, Ruben Niesvizky, Djordje Atanackovic, Mohamed Salama, Karen Curtin, Selina Chen-Kiang, Jude Phillip, Jayeshkumar Patel, Agnes Viale, Mykyta Artomov, Rosalie G. Waller, Dina Becirovic, Lauren M. Jacobs, David S. Jayabalan, Shu-Ping Wang, James D. McKay, Celine M. Vachon, Carrie Snyder, Vijai Joseph, Kim E. Nichols, Michael F. Walsh, Jinghui Zhang, Jian Sun, Maria V. Revuelta, Gang Wu, Siwei Chen, M. Nieves Calvo-Vidal, Xiaomu Wei
Clinical characteristics of familial myeloma probands who were studied with germline whole exome sequencing.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6df7cb64b7f19d76ead355dfb784944
https://doi.org/10.1158/0008-5472.22415838.v1
https://doi.org/10.1158/0008-5472.22415838.v1
Autor:
Steven M. Lipkin, Leandro Cerchietti, Haiyuan Yu, Robert J. Klein, Kenneth Offit, Nicola J. Camp, Charles G. Mullighan, Henry T. Lynch, Charles Dumontet, Robert G. Roeder, Mark J. Daly, Kenneth C. Anderson, Judy E. Garber, Jane Churpek, Lucy A. Godley, Susan L. Slager, Ola Landgren, Ruben Niesvizky, Djordje Atanackovic, Mohamed Salama, Karen Curtin, Selina Chen-Kiang, Jude Phillip, Jayeshkumar Patel, Agnes Viale, Mykyta Artomov, Rosalie G. Waller, Dina Becirovic, Lauren M. Jacobs, David S. Jayabalan, Shu-Ping Wang, James D. McKay, Celine M. Vachon, Carrie Snyder, Vijai Joseph, Kim E. Nichols, Michael F. Walsh, Jinghui Zhang, Jian Sun, Maria V. Revuelta, Gang Wu, Siwei Chen, M. Nieves Calvo-Vidal, Xiaomu Wei
PCA and gene based rare synonymous variant comparison analyses of European ancestry Multiple Myeloma cases and controls
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b6edc68f473dc9ce25d3205f8329f86
https://doi.org/10.1158/0008-5472.22415844
https://doi.org/10.1158/0008-5472.22415844
Autor:
Maureen E. Lane, Morton Coleman, Selina Chen-Kiang, Donna Skerret, Scott Ely, Zhaoying Xiang, Karen Pekle, Faiza Zafar, Tsiporah B. Shore, Lena Mathews, Paul J. Christos, Jessica Stern, Megan Manco, Roger N. Pearse, David S. Jayabalan, Maureen Ward, Tomer M. Mark, Ruben Niesvizky
PDF file - 53K, Validation of gene expression data using QPCR compared to microarray values (data reported as fold change).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cd424e4842520d88c910511e4e34e30
https://doi.org/10.1158/1078-0432.22451295.v1
https://doi.org/10.1158/1078-0432.22451295.v1
Autor:
Lorenzo Galluzzi, Silvia C. Formenti, Selina Chen-Kiang, Maurizio Di Liberto, Norma Bloy, Takahiro Yamazaki, Aitziber Buqué, Giulia Petroni
Legends to Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eaf71e668e364de921982839673ebf1
https://doi.org/10.1158/1078-0432.22480280.v1
https://doi.org/10.1158/1078-0432.22480280.v1