Výsledky vyhledávání - "Self-Injurious Behavior/genetics"

Simultaneous analysis of serotonin transporter, tryptophan hydroxylase 1 and 2 gene expression in the ventral prefrontal cortex of suicide victims

Autor: Elizabeth Neidhart, Térèse Laforge, Romano La Harpe, Nader Perroud, Alain Malafosse, Brice Petit, Monique Vessaz, Céline Relecom, Michel Guipponi

Publikováno v: American Journal of Medical Genetics. B, Vol. 153B, No 4 (2010) pp. 909-918

Serotonergic signaling abnormalities have been implicated in suicide. Tryptophan hydroxylase (TPH), the rate limiting enzyme of serotonin biosynthesis and the serotonin transporter (SLC6A4), involved in the reuptake of serotonin from the synaptic gap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5256214835b9c93ceec93538014396b7
https://archive-ouverte.unige.ch/unige:21210

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Genes, suicide and decisions

Autor: Fabrice Jollant, Alain Malafosse, Sébastien Guillaume, P. Courtet

Publikováno v: European Psychiatry, Vol. 25, No 5 (2010) pp. 294-296

ObjectiveA better understanding of the pathophysiology of suicidal behaviour (SB) may enable the discovery of more specific treatments and a better identification of vulnerable patients. The vulnerability to SB appears to be underlied by genetic fact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3948ba9762d715c36c9acb0f6d861fa9
https://archive-ouverte.unige.ch/unige:20859

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Genetic and epigenetic analysis of SSAT gene dysregulation in suicidal behavior

Autor: Térèse Laforge, Samuel Deutsch, Sébastien Guillaume, Nader Perroud, Philippe Courtet, Michel Guipponi, Fabrice Jollant, François Le Gal, Patrick Baud, Karine Kohler, Brice Petit, Romano La Harpe, Alain Malafosse, Monique Vessaz

Publikováno v: American Journal of Medical Genetics. B, Vol. 150B, No 6 (2009) pp. 799-807

It has recently been proposed that the SSAT gene plays a role in the predisposition to suicidal behavior. SSAT expression was found to be down-regulated in the brain of suicide completers. In addition, a single nucleotide polymorphism (SNP) rs6526342

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2f38029f63165417e6448fd8006a27a
https://archive-ouverte.unige.ch/unige:5516

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