Biologically Informed Polygenic Scores for Brain Insulin Receptor Network Are Associated with Cardiometabolic Risk Markers and Diabetes in Women.

Autor: Selenius JS; Folkhälsan Research Center, Helsinki, Finland.; Department of General Practice and Primary Health Care, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Silveira PP; Department of Psychiatry, Faculty of Medicine, McGill University, Verdun, QC, Canada.; Ludmer Center for Neuroinformatic and Mental Health, Douglas Mental Health University Institute, McGill University, Verdun, QC, Canada., Bonsdorff MV; Folkhälsan Research Center, Helsinki, Finland.; Gerontology Research Center and Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland., Lahti J; Department of Psychology and Logopedics, University of Helsinki, Helsinki, Finland.; Turku Institute for Advanced Studies, University of Turku, Turku, Finland., Koistinen H; Department of Clinical Chemistry and Haematology, Helsinki University Hospital, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Koistinen R; Department of Clinical Chemistry and Haematology, Helsinki University Hospital, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Seppälä M; Department of Clinical Chemistry and Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Eriksson JG; Folkhälsan Research Center, Helsinki, Finland.; Department of General Practice and Primary Health Care, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.; Department of Obstetrics & Gynecology and Human Potential Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore., Wasenius NS; Folkhälsan Research Center, Helsinki, Finland.; Department of General Practice and Primary Health Care, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.

Publikováno v: Diabetes & metabolism journal [Diabetes Metab J] 2024 Sep; Vol. 48 (5), pp. 960-970. Date of Electronic Publication: 2024 Mar 25.

The relationship between health-related quality of life and melancholic depressive symptoms is modified by brain insulin receptor gene network.

Autor: Selenius JS; Folkhälsan Research Center, Finbyntie 136 Karjaa, 10300, Helsinki, Finland. jannica.selenius@helsinki.fi.; Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. jannica.selenius@helsinki.fi., Silveira PP; Department of Psychiatry, Faculty of Medicine, McGill University, 6875 Boulevard LaSalle, Verdun, QC, H4H1R3, Canada.; Ludmer Centre for Neuroinformatic and Mental Health, Douglas Mental Health University Institute, McGill University, 6875 Boulevard LaSalle, Verdun, QC, H4H1R3, Canada., Salonen M; Folkhälsan Research Center, Finbyntie 136 Karjaa, 10300, Helsinki, Finland.; Public Health Promotion Unit, The National Institute for Health and Welfare, Helsinki, Finland., Kautiainen H; Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., von Bonsdorff M; Folkhälsan Research Center, Finbyntie 136 Karjaa, 10300, Helsinki, Finland.; Gerontology Research Center and Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland., Kajantie E; National Institute for Health and Welfare, Public Health Promotion Unit, Helsinki, Oulu, Finland.; PEDEGO Research Unit, MRC Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.; Children's Hospital, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway., Lahti J; Department of Psychology and Logopedics, University of Helsinki, P.O. Box 63, 00014, Helsinki, Finland.; Turku Institute for Advanced Studies, University of Turku, 20014, Turku, Finland., Eriksson JG; Folkhälsan Research Center, Finbyntie 136 Karjaa, 10300, Helsinki, Finland.; Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Department of Obstetrics and Gynecology and Human Potential Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Wasenius NS; Folkhälsan Research Center, Finbyntie 136 Karjaa, 10300, Helsinki, Finland.; Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Publikováno v: Scientific reports [Sci Rep] 2021 Nov 03; Vol. 11 (1), pp. 21588. Date of Electronic Publication: 2021 Nov 03.

Unexpectedly High Prevalence of Common Variable Immunodeficiency in Finland.

Autor: Selenius JS; Folkhälsan Institute of Genetics, Helsinki, Finland.; Adult Immunodeficiency Unit, Infectious Diseases, Inflammation Center, University of Helsinki, Helsinki University Hospital, Helsinki, Finland., Martelius T; Adult Immunodeficiency Unit, Infectious Diseases, Inflammation Center, University of Helsinki, Helsinki University Hospital, Helsinki, Finland., Pikkarainen S; Department of Gastroenterology, University of Helsinki, Helsinki University Hospital, Helsinki, Finland., Siitonen S; Laboratory Services, Hospital District of Helsinki and Uusimaa Laboratory, University of Helsinki, Helsinki University Hospital, Helsinki, Finland., Mattila E; Adult Immunodeficiency Unit, Infectious Diseases, Inflammation Center, University of Helsinki, Helsinki University Hospital, Helsinki, Finland., Pietikäinen R; Department of Infectious Diseases, Kymenlaakso Central Hospital, Kotka, Finland., Suomalainen P; Department of Infectious Diseases, South Karelia Central Hospital, South Karelia Social and Health Care District, Lappeenranta, Finland., Aalto AH; Department of Infectious Diseases, South Karelia Central Hospital, South Karelia Social and Health Care District, Lappeenranta, Finland.; Department of Medicine, Kuopio University Hospital, Kuopio, Finland., Saarela J; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Einarsdottir E; Folkhälsan Institute of Genetics, Helsinki, Finland.; Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden.; Molecular Neurology Research Program, University of Helsinki, Helsinki, Finland., Järvinen A; Adult Immunodeficiency Unit, Infectious Diseases, Inflammation Center, University of Helsinki, Helsinki University Hospital, Helsinki, Finland., Färkkilä M; Department of Gastroenterology, University of Helsinki, Helsinki University Hospital, Helsinki, Finland., Kere J; Folkhälsan Institute of Genetics, Helsinki, Finland.; Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden.; Molecular Neurology Research Program, University of Helsinki, Helsinki, Finland.; Department of Medical and Molecular Genetics, King's College London, London, United Kingdom., Seppänen M; Adult Immunodeficiency Unit, Infectious Diseases, Inflammation Center, University of Helsinki, Helsinki University Hospital, Helsinki, Finland.; Rare Disease Center, Children's Hospital, University of Helsinki, Helsinki University Hospital, Helsinki, Finland.

Publikováno v: Frontiers in immunology [Front Immunol] 2017 Sep 28; Vol. 8, pp. 1190. Date of Electronic Publication: 2017 Sep 28 (Print Publication: 2017).