A Power Prior Approach for Leveraging External Longitudinal and Competing Risks Survival Data Within the Joint Modeling Framework

Autor: Ming-Hui Chen, Jonathan Gelfond, Md. Tuhin Sheikh, Joseph G. Ibrahim

Publikováno v: Statistics in Biosciences. 14:318-336

In this paper, we propose a new partial borrowing-by-parts power prior for carrying out the analysis of co-longitudinal and survival data within the joint modeling framework. The borrowing-by-parts power prior facilitates borrowing the information fr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d371c1c1d516c264cb4604e356b90e54
https://doi.org/10.1007/s12561-021-09330-6

Joint modelling of longitudinal and survival data in the presence of competing risks with applications to prostate cancer data

Autor: Jonathan Gelfond, Wei Sun, Ming-Hui Chen, Joseph G. Ibrahim, Tuhin Sheikh

Publikováno v: Stat Modelling

This research is motivated from the data from a large Selenium and Vitamin E Cancer Prevention Trial (SELECT). The prostate specific antigens (PSAs) were collected longitudinally, and the survival endpoint was the time to low-grade cancer or the time

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17c9d86d71c1313c00df1600f713a9ea
https://europepmc.org/articles/PMC8225229/

A Prospective Study of Chronic Inflammation in Benign Prostate Tissue and Risk of Prostate Cancer: Linked PCPT and SELECT Cohorts

Autor: Howard L. Parnes, Angelo M. De Marzo, Ian M. Thompson, Charles G. Drake, Scott M. Lippman, Eric A. Klein, Elizabeth A. Platz, John R. Barber, Ibrahim Kulac, M. Scott Lucia, Phyllis J. Goodman, Corinne E. Joshu, Catherine M. Tangen, William G. Nelson

Publikováno v: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, vol 26, iss 10

Background: We leveraged two trials to test the hypothesis of an inflammation–prostate cancer link prospectively in men without indication for biopsy. Methods: Prostate Cancer Prevention Trial (PCPT) participants who had an end-of-study biopsy perf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f3d9ba859fd910734fb376ec17853d3
https://doi.org/10.1158/1055-9965.epi-17-0503

Organoids Increase the Predictive Value of in vitro Cancer Chemoprevention Studies for in vivo Outcome

Autor: Rose N. Njoroge, Rajita J. Vatapalli, Sarki A. Abdulkadir

Publikováno v: Frontiers in Oncology
Frontiers in Oncology, Vol 9 (2019)

Epidemiological and preclinical data suggest that antioxidants are protective against prostate cancer whose pathogenesis has been linked to oxidative stress. However, the selenium and vitamin E Cancer Prevention Trial (SELECT), found no efficacy for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f689503ae1f164f39581b75ebc3374c
https://doi.org/10.3389/fonc.2019.00077

Selenium- or Vitamin E–Related Gene Variants, Interaction with Supplementation, and Risk of High-Grade Prostate Cancer in SELECT

Autor: Alex M. Tinianow, Eric A. Klein, Amy K. Darke, Sam Peisch, Ian M. Thompson, Tong Sun, Gwo-Shu Mary Lee, Lorelei A. Mucci, June M. Chan, James M. Rae, Philip W. Kantoff, Phyllis J. Goodman, Catherine M. Tangen, Kathryn L. Penney

Publikováno v: Cancer Epidemiology, Biomarkers & Prevention. 25:1050-1058

Background: Epidemiologic studies and secondary analyses of randomized trials supported the hypothesis that selenium and vitamin E lower prostate cancer risk. However, the Selenium and Vitamin E Cancer Prevention Trial (SELECT) showed no benefit of e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c94f8d0a64401247d55c7457d2461a8
https://doi.org/10.1158/1055-9965.epi-16-0104