Výsledky vyhledávání - "Selene K Swanson"

Akademický článek

Yeast Nuak1 phosphorylates histone H3 threonine 11 in low glucose stress by the cooperation of AMPK and CK2 signaling

Autor: Seunghee Oh, Jaehyoun Lee, Selene K Swanson, Laurence Florens, Michael P Washburn, Jerry L Workman

Publikováno v: eLife, Vol 9 (2020)

Changes in available nutrients are inevitable events for most living organisms. Upon nutritional stress, several signaling pathways cooperate to change the transcription program through chromatin regulation to rewire cellular metabolism. In budding y

Externí odkaz: https://doaj.org/article/332fffdb5a464fb5a13bd15d383c97c2

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Akademický článek

Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis.

Publikováno v: PLoS Pathogens, Vol 13, Iss 10, p e1006668 (2017)

Merkel cell carcinoma (MCC) frequently contains integrated copies of Merkel cell polyomavirus DNA that express a truncated form of Large T antigen (LT) and an intact Small T antigen (ST). While LT binds RB and inactivates its tumor suppressor functio

Externí odkaz: https://doaj.org/article/09d9ce0281074c5285116f21831c3c3c

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Akademický článek

The human cytoplasmic dynein interactome reveals novel activators of motility

Autor: William B Redwine, Morgan E DeSantis, Ian Hollyer, Zaw Min Htet, Phuoc Tien Tran, Selene K Swanson, Laurence Florens, Michael P Washburn, Samara L Reck-Peterson

Publikováno v: eLife, Vol 6 (2017)

In human cells, cytoplasmic dynein-1 is essential for long-distance transport of many cargos, including organelles, RNAs, proteins, and viruses, towards microtubule minus ends. To understand how a single motor achieves cargo specificity, we identifie

Externí odkaz: https://doaj.org/article/a142aea420de4a60919607041fbe4840

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Akademický článek

Trio, a Rho Family GEF, Interacts with the Presynaptic Active Zone Proteins Piccolo and Bassoon.

Autor: Ryan T Terry-Lorenzo, Viviana I Torres, Dhananjay Wagh, Jose Galaz, Selene K Swanson, Laurence Florens, Michael P Washburn, Clarissa L Waites, Eckart D Gundelfinger, Richard J Reimer, Craig C Garner

Publikováno v: PLoS ONE, Vol 11, Iss 12, p e0167535 (2016)

Synaptic vesicles (SVs) fuse with the plasma membrane at a precise location called the presynaptic active zone (AZ). This fusion is coordinated by proteins embedded within a cytoskeletal matrix assembled at the AZ (CAZ). In the present study, we have

Externí odkaz: https://doaj.org/article/c98af2f3e56245ee872e4c61b972e3f2

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Akademický článek

Combinatorial depletion analysis to assemble the network architecture of the SAGA and ADA chromatin remodeling complexes

Autor: Kenneth K Lee, Mihaela E Sardiu, Selene K Swanson, Joshua M Gilmore, Michael Torok, Patrick A Grant, Laurence Florens, Jerry L Workman, Michael P Washburn

Publikováno v: Molecular Systems Biology, Vol 7, Iss 1, Pp 1-12 (2011)

Abstract Despite the availability of several large‐scale proteomics studies aiming to identify protein interactions on a global scale, little is known about how proteins interact and are organized within macromolecular complexes. Here, we describe

Externí odkaz: https://doaj.org/article/30608059df1c45e9ac84cb22d8697a2b

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Akademický článek

Lentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infection.

Autor: Smita Srivastava, Selene K Swanson, Nicolas Manel, Laurence Florens, Michael P Washburn, Jacek Skowronski

Publikováno v: PLoS Pathogens, Vol 4, Iss 5, p e1000059 (2008)

Vpx is a small virion-associated adaptor protein encoded by viruses of the HIV-2/SIVsm lineage of primate lentiviruses that enables these viruses to transduce monocyte-derived cells. This probably reflects the ability of Vpx to overcome an as yet unc

Externí odkaz: https://doaj.org/article/38694efc741c401cb77abf1076150e69

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Akademický článek

The inhibition of polo kinase by matrimony maintains G2 arrest in the meiotic cell cycle.

Autor: Youbin Xiang, Satomi Takeo, Laurence Florens, Stacie E Hughes, Li-Jun Huo, William D Gilliland, Selene K Swanson, Kathy Teeter, Joel W Schwartz, Michael P Washburn, Sue L Jaspersen, R Scott Hawley

Publikováno v: PLoS Biology, Vol 5, Iss 12, p e323 (2007)

Many meiotic systems in female animals include a lengthy arrest in G2 that separates the end of pachytene from nuclear envelope breakdown (NEB). However, the mechanisms by which a meiotic cell can arrest for long periods of time (decades in human fem

Externí odkaz: https://doaj.org/article/72c7a1a0309a4c889f589f837e437108

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