Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Selene, Araya"'
Autor:
Odermatt, Simon Stücheli, Selene Araya, Caner Ercan, Seraina O. Moser, John Gallon, Paul Jenö, Salvatore Piscuoglio, Luigi Terracciano, Alex
Publikováno v:
Cancers; Volume 14; Issue 13; Pages: 3074
Prostate cancer (PCa), one of the most common malignancies in men, typically responds to initial treatment, but resistance to therapy often leads to metastases and death. The dehydrogenase/reductase 7 (DHRS7, SDR34C1) is an “orphan” enzyme withou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::fca352853acb64ed34e12aec1ae4ac13
Autor:
Simon, Stücheli, Selene, Araya, Caner, Ercan, Seraina O, Moser, John, Gallon, Paul, Jenö, Salvatore, Piscuoglio, Luigi, Terracciano, Alex, Odermatt
Publikováno v:
Cancers. 14(13)
Prostate cancer (PCa), one of the most common malignancies in men, typically responds to initial treatment, but resistance to therapy often leads to metastases and death. The dehydrogenase/reductase 7 (DHRS7, SDR34C1) is an "orphan" enzyme without kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1609b732359489454d42ad68c79ec3e6
https://pubmed.ncbi.nlm.nih.gov/35804847
https://pubmed.ncbi.nlm.nih.gov/35804847
Publikováno v:
Journal of applied toxicology : JATREFERENCES. 42(9)
Contract Development and Manufacturing Organizations (CDMOs) that manufacture large, diverse portfolio of chemical and pharmaceutical substances require pragmatic risk-based decisions with respect to the safe carry-over between different chemical ent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44b2e32dee87a5edd6007ccccbf070fb
https://pubmed.ncbi.nlm.nih.gov/35315528
https://pubmed.ncbi.nlm.nih.gov/35315528
Autor:
Rolf Graf, Simone M. R. Camargo, Selene Araya, Evelyne Kuster, Theresia Reding, Christian Lutz, Dino Gluch, François Verrey, Luca Mariotta
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 314:G517-G536
Glutamine (Gln) is the most concentrated amino acid in blood and considered conditionally essential. Its requirement is increased during physiological stress, such as malnutrition or illness, despite its production by muscle and other organs. In the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4541ea9387a67541a21686f389bde896
https://doi.org/10.1152/ajpgi.00135.2017
https://doi.org/10.1152/ajpgi.00135.2017
Publikováno v:
Regulatory Toxicology and Pharmacology. 73:515-520
Pharmaceutical intermediates (IM) are used in the synthesis of active pharmaceutical ingredients. They are not intended for human administration, yet employees may be exposed to IM during the manufacturing process. In the context of occupational heal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db08850df4c278f227dfb98735ae134
https://doi.org/10.1016/j.yrtph.2015.10.001
https://doi.org/10.1016/j.yrtph.2015.10.001
Autor:
Denise V. Kratschmar, Alex Odermatt, Simon Stücheli, Maria Tsachaki, Selene Araya, Katharina Beck
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 171
DHRS7 (SDR34C1) has been associated with potential tumor suppressor effects in prostate cancer; however, its function remains largely unknown. Recent experiments using purified recombinant human DHRS7 suggested several potential substrates, including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07ea06a359916035ccc6d0bdfcfed50
https://pubmed.ncbi.nlm.nih.gov/28457967
https://pubmed.ncbi.nlm.nih.gov/28457967
Publikováno v:
European Journal of Molecular and Clinical Medicine, Vol 2, Iss 2 (2015)
In order to assess the occupational health hazard of intermediates (IM), hazard data were traditionally generated through experimental animal testing, which are more and more replaced by alternative methods considering animal welfare and costs. Indee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f34606eec1edc050c7d3354afc6cb58b
https://www.ejmcm.com/articles/204
https://www.ejmcm.com/articles/204
Autor:
Selene Araya, Ester Lovsin Barle, Gian Christian Winkler, Rudolf Bechter, Christopher Perino, Martin Kuster
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 72(3)
Workers in development and manufacturing of pharmaceuticals are at risk for occupational contact dermatitis (OCD) of irritative (ICD) or allergic (ACD) origin, due to contacts with reactive intermediates (IM) and drug substances (DS). We examined, if
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7147acb56acdc38594c3a76102dad435
https://pubmed.ncbi.nlm.nih.gov/26028366
https://pubmed.ncbi.nlm.nih.gov/26028366
Publikováno v:
Toxicology Letters. 229:S251
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bff211a5be587ea60bf3dad2c71c1512
https://doi.org/10.1016/j.toxlet.2014.06.831
https://doi.org/10.1016/j.toxlet.2014.06.831
Autor:
Rolf Graf, François Verrey, Simone M. R. Camargo, Theresia Reding, Selene Araya, Evelyne Kuster
Publikováno v:
Pancreatology. 14:S120
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc7cad81b0a9566d5f5e5432c5fc75c0
https://doi.org/10.1016/j.pan.2014.05.788
https://doi.org/10.1016/j.pan.2014.05.788